Beta Blocker News and Research

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Beta-adrenergic receptor blocking agents (beta-blockers) are drugs with multiple actions on the heart. Blockade of beta-1 receptors results in slowing of heart rate, reduction in myocardial contractility, and lowering of systemic blood pressure. In the context of acute myocardial infarction (AMI), which represents a state of reduced oxygen supply to the affected portion of the heart, these effects may be beneficial as they result in reduced myocardial workload and oxygen demand. Furthermore, beta-blockers may reduce the risk of ventricular arrhythmias, which are an important cause of death following AMI.

Heart patients don't stick to drug programs

A new report says that although people with coronary artery disease (CAD) are now more likely to use evidence-based therapies than they were a few years ago, there is still room for improvement.

10 Jan 2006

Coronary artery disease patients consistently fail to take life saving drugs

Nearly half the coronary artery disease (CAD) patients in a seven-year study admitted they don’t consistently take beta blockers, cholesterol-lowering drugs and other medications that could extend their lives, researchers report in Circulation: Journal of the American Heart Association.

10 Jan 2006

Quality of care for acute myocardial infarction in elderly patients with alcohol-related diagnoses

Older Americans with alcohol problems do not get worse treatment than their sober peers when they are hospitalized for a heart attack, according to new research on Medicare patients across the country.

6 Jan 2006

Pharmacogenetics can reduce health care costs

Chances are good that a medication you take is one of several drugs that can be affected by genetic factors, according to researchers at Washington University School of Medicine in St. Louis and the St. Louis College of Pharmacy.

5 Jan 2006

Post cardiac surgery heart irregularities reduced by medication

Use of the medication amiodarone is associated with one-half the incidence of atrial tachyarrhythmias (rapid, abnormal heart beat) following cardiac surgery, according to a study in the December 28 issue of JAMA.

28 Dec 2005

Implantable defibrillators benefit women as much as men after heart attack

Women who have had a heart attack get as much survival benefit as men from implanted cardioverter defibrillators (ICDs), devices designed to monitor the heart's pumping rhythm and shock it back to normal when needed, according to a study published in the December edition of the Journal of Cardiovascular Electrophysiology.

22 Dec 2005

Physicians slow to prescribe newer heart drugs

An analysis of the treatment received by more than 100,000 heart patients has shown that physicians' prescription practices for drugs proven effective for treating heart disease has shown steady improvement over the past three years, cardiologists at the Duke Clinical Research Institute (DCRI) have concluded.

7 Dec 2005

New insights into treatment of hypertension in black Americans

Researchers have reported a possible explanation for the higher risk of heart disease and its complications among black Americans, along with a way of treating this condition.

6 Dec 2005

Aldosterone shows promise as stroke treatment

A bi-polar hormone that can contribute to strokes and minimize their damage is emerging as a therapeutic target in the battle against these brain attacks, researchers say.

5 Dec 2005

"Get With The Guidelines" programs improve care

After one year - Get With The GuidelinesSM programs used in hospitals significantly improved care for almost 30,000 coronary artery disease patients of all ages and sexes, according to research reported at the American Heart Association's Scientific Sessions 2005.

26 Nov 2005

Beta-blockers may help deal with stress

An experience as simple as watching graphically violent or emotional scenes in a movie can induce enough stress to interfere with problem-solving abilities, new research at Ohio State University Medical Center suggests.

20 Nov 2005

Lack of aggressive treatment for clogged leg blood vessels means missed heart attack prevention opportunity

Despite the fact that clogged arteries in the legs usually mean clogged arteries near the heart, doctors often fail to give heart-protecting drugs to people with severe leg blood vessel blockages, a new University of Michigan-led study finds.

15 Nov 2005

Study suggests that some patients on beta blockers should not be

A Johns Hopkins study has raised doubts about a long-accepted notion of what's going on in many cases of heart failure, suggesting that nearly half of patients with the disorder may be getting the wrong treatment for their disease.

15 Nov 2005

Blood pressure near the heart is more predictive of cardiovascular outcomes than blood pressure measured in the arm

Results from a new study show that amlodipine-based (calcium channel blocker) treatment is much more effective at reducing blood pressure near the heart than a conventional atenolol-based (beta blocker) regimen.

14 Nov 2005

Norvasc better than beta blockers for lowering blood pressure

According to a study presented at a meeting of the American Heart Association, Norvasc, was more effective at reducing blood pressure near the heart than standard, older treatments such as beta blockers.

14 Nov 2005

Early diagnosis and treatment of heart disease may lead to longer life in Duchenne and Becker muscular dystrophy patients

Cardiac disease, particularly dilated cardiomyopathy and heart failure, is the major cause of mortality in patients with muscular dystrophy and is present in most boys with Duchenne muscular dystrophy and approximately 70 percent of those with Becker muscular dystrophy. These are the two common forms of muscular dystrophy caused by defects in a gene called dystrophin.

30 Oct 2005

Beta blockers not as effective as other drugs that reduce high blood pressure in patients with hypertension

Beta blockers are not as effective as other drugs that reduce high blood pressure in patients with hypertension, concludes a meta-analysis published online by The Lancet.

18 Oct 2005

More doubt cast on benefit of beta blockers for high blood pressure

A comprehensive study has produced more evidence that a drug widely used to treat high blood pressure may not be the best option for many patients.

18 Oct 2005

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

Quality-improvement improves mortality in hospital

Heart attack death rates dropped significantly at hospitals that participated in a quality-improvement process that increased the use of evidence-based therapies, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005