Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Chronic periodontitis linked to head and neck cancer

Chronic periodontitis, a form of gum disease, is an independent risk factor for head and neck squamous cell carcinoma. This suggests the need for increased efforts to prevent and treat periodontitis as a possible means to reduce the risk of this form of cancer.

8 Sep 2009

New ARRA-funded research on white blood cell functioning

The American Recovery and Reinvestment Act (ARRA) has provided funding for new research to learn more about how white blood cells work. Jonathan Reichner, PhD, of the department of surgery at Rhode Island Hospital has received a grant from the National Institutes of Health with funding through the American Recovery and Reinvestment Act. Reichner's hope is that the research will lead to new immune-enhancing therapies, with potential implications for improvements in both cancer treatment and controlling inflammation accompanying injury and infection.

2 Sep 2009

VBI researcher receives grant from NIGMS for developing network-based models of infectious diseases

A researcher from the Virginia Bioinformatics Institute (VBI) at Virginia Tech has received a grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health (NIH), to support ongoing work to develop high-performance computer models for the study of very large networks.

1 Sep 2009

GenoCAD project receives financial support from NSF

The National Science Foundation (NSF) has awarded a three-year $1,421,725 grant to Jean Peccoud, associate professor at the Virginia Bioinformatics Institute at Virginia Tech, to develop GenoCAD - a web-based Computer Assisted Design environment for synthetic biology.

1 Sep 2009

Study provides insights into genes that help maintain youthfulness of the skin

In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome."

1 Sep 2009

Illumina delivers its first individual genome sequence to Dr. Hermann Hauser

Illumina, Inc. today announced that it has delivered Hermann Hauser’s genome sequence. Dr. Hauser, Partner, Amadeus Capital Partners Ltd, is the first consumer to purchase Illumina’s individual genome sequencing service working with his physician, Michael Nova, MD, of Pathway Genomics.

From Illumina, Inc. 31 Aug 2009

Psychogenics and Astrazeneca sign agreement to identify new compounds for treating Central Nervous System disorders

PsychoGenics Inc. and AstraZeneca have entered into a drug discovery and development agreement to identify compounds that are likely to be useful for the treatment of certain Central Nervous System (CNS) disorders.

31 Aug 2009

Enzymes could be targeted to kill dangerous pathogens

Researchers at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have demonstrated that an enzyme that is essential to many bacteria can be targeted to kill dangerous pathogens.

28 Aug 2009

New software programs improve the cancer biomarker identification process

caCORRECT and omniBioMarker programs earn silver-level compatibility certification from NIH/National Cancer Institute's cancer Bioinformatics Grid

19 Aug 2009

Chemists rationally design inhibitors against an RNA molecule that causes myotonic muscular dystrophy

Chemists at the University at Buffalo have used rational drug design to synthesize small, cell-permeable molecules that are effective in vitro against two common types of myotonic muscular dystrophy, a result that has implications for potentially curing muscular dystrophy, as well as other diseases.

9 Aug 2009

Expression Analysis launches new look

The url stays the same, but www.ExpressionAnalysis.com looks a lot different today. The redesigned website allows researchers and scientists to more easily navigate and locate the information and services they are looking for, in most cases in just one click. Additionally a revamped search tool enables users to find valuable information on a wide range of scientific topics.

6 Aug 2009

New software provides a better understanding of how viruses evolve

Computer scientists and biologists at the University of Southampton have used the combined power of computing resources within the institution to develop software which provides a better understanding of how viruses evolve.

23 Jul 2009

New UK national genome centre

A new UK national genome centre was officially opened by Nobel Laureate and genome pioneer Prof Sir John Sulston and the Lord-Lieutenant of Norfolk.

5 Jul 2009

Major new e-science resource for biologists

The University of Manchester and the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) have launched a major new e-science resource for biologists - which could accelerate research into treatments for H1N1 flu and cancer.

From The University of Manchester 2 Jul 2009

Researchers using microRNA to identify aggressive melanoma

Research at the University of Leicester will be breaking new ground in the search for a simple blood test that could tell whether a patient with melanoma has the condition in an aggressive form.

30 Jun 2009

First health study of teenage boys using cellular telephones

A $4.15 million, four-year National Institutes of Health grant will enable researchers at the Indiana University School of Medicine to conduct the first health study of teenage boys using cellular telephones.

16 Jun 2009

Scientists launch Gene Expression Atlas

Today, researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.

15 Jun 2009

A new method for breast cancer biomarker discovery

Three researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed and evaluated a new one-step bioanalytical approach that allows them to profile in detail complex cellular extracts of proteins. The method has allowed the scientists to look at how the levels of proteins change in breast cancer cells when they are treated with hormones or cancer drugs like tamoxifen.

9 Jun 2009

Oxidative stress strongly evident in the in-utero environment of the fetus with Down syndrome

A paper published in the Proceedings of the National Academy of Sciences by Tufts Medical Center and Tufts University researchers reports that amniotic fluid surrounding Down syndrome fetuses shows oxidative stress, a condition that could harm fetal cells and play a role in affected individuals. The results demonstrate secondary adverse consequences of Down syndrome and suggest potential prenatal therapies.

2 Jun 2009

Scientists map sequence mutations of the 2009 H1N1 influenza A virus

In just two weeks from the time the first patient virus samples were made available, Singapore scientists report an evolutionary analysis of a critical protein produced by the 2009 H1N1 influenza A virus strain.

22 May 2009