Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Fecal microbiota transplantation more successful for treating Clostridium difficile infections

Distasteful though it sounds, the transplantation of fecal matter is more successful for treating Clostridium difficile infections than previously thought.

30 Mar 2015

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

Agena Bioscience today released the LungFUSION Panel for rapid and sensitive identification of oncogenic ALK, RET, and ROS1 gene fusions in non-small cell lung cancer tumors.

25 Mar 2015

New study reveals how cells sort out loops meant to encode microRNAs

Just as two DNA strands naturally arrange themselves into a helix, DNA's molecular cousin RNA can form hairpin-like loops. But unlike DNA, which has a single job, RNA can play many parts -- including acting as a precursor for small molecules that block the activity of genes. These small RNA molecules must be trimmed from long hairpin-loop structures, raising a question: How do cells know which RNA loops need to be processed this way and which don't?

25 Mar 2015

Key finding may point to immediate cause of CF exacerbations

In the genetic disorder cystic fibrosis (CF), the most severe symptoms are recurring episodes of lung inflammation and bacterial infection (known as "exacerbations") that happen from one to three times a year and cause ever-increasing amounts of lung damage through the course of a CF patient's life.

24 Mar 2015

TGAC plans to use miniaturised sequencing device to conduct live environmental surveillance

As one of the first research Institutes to take part in the MinION Access Programme (MAP) for portable DNA sequencing, introduced by Oxford Nanopore Technologies, The Genome Analysis Centre (TGAC)'s task force share their experience of the ground breaking trial so far.

From Oxford Nanopore Technologies 23 Mar 2015

Los Alamos scientists develop new method for metagenomic analysis

Scientists at Los Alamos National Laboratory have developed a new method for DNA analysis of microbial communities such as those found in the ocean, the soil, and our own guts.

19 Mar 2015

GenomeNext completes whole genome sequencing analysis at unprecedented 1,000 genomes per day

GenomeNext, LLC, a leader in genomic data management and integrated analysis, announced today that, through the "Intel Heads In The Clouds Challenge on Amazon Web Services" with support from JHC Technology, and in conjunction with Nationwide Children's Hospital, has benchmarked whole genome sequencing analysis at an unprecedented 1,000 genomes per day.

18 Mar 2015

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

NantWorks, Inc. and Sorrento Therapeutics, Inc., announced today that they have entered into a binding agreement to initiate a global collaboration to discover and develop novel anti-cancer immunotherapies derived from Sorrento's proprietary G-MAB library against neoepitopes of tumor-specific antigens discovered using NantWorks' proprietary pan-omics based, precision medicine approach.

16 Mar 2015

Study: Listening to classical music improves activity of genes involved in brain functions

Although listening to music is common in all societies, the biological determinants of listening to music are largely unknown. According to a latest study, listening to classical music enhanced the activity of genes involved in dopamine secretion and transport, synaptic neurotransmission, learning and memory, and down-regulated the genes mediating neurodegeneration.

13 Mar 2015

Research findings offer new insights into pathophysiology of PTSD

Researchers at the Veterans Affairs San Diego Healthcare System and University of California, San Diego School of Medicine, with colleagues in New York and the United Kingdom, have identified genetic markers, derived from blood samples that are linked to post-traumatic stress disorder (PTSD). The markers are associated with gene networks that regulate innate immune function and interferon signaling.

11 Mar 2015

New tool provides molecular details about how mutations affect cellular processes

Today in the journal Nature Methods, the laboratory headed by ICREA researcher Patrick Aloy, at the Institute for Research in Biomedicine, presents a computational tool that allows a greater understanding of the genetic causes of complex diseases such as cancer, Alzheimer's and diabetes.

27 Feb 2015

Beckman Coulter Genomics Introduces a Scalable RNA-seq service line for processing intact and degraded RNA samples

This fully automated sample preparation pipeline delivers consistent results run after run, reducing user variability and bias and allows processing of a large amount of samples with reduced turnaround time relative to manual library construction.

25 Feb 2015

Researchers find that new targeted drugs can attack weak spots in cancer cells

Scientists have identified weak spots in cancer cells that could be targeted and attacked by new precision drugs.

25 Feb 2015

Agena releases MassARRAY 24-Well System for mass spectrometry-based genetic testing

Agena Bioscience today released the MassARRAY 24-Well System for mass spectrometry-based genetic analysis, adding to its existing MassARRAY portfolio. The new 24-well format is tailored to smaller clinical testing laboratories requiring modest sample throughput, reduced initial hardware costs, and reduced time to result.

24 Feb 2015

MRIGlobal awarded contract to develop Sample-to-Sequence system for diagnosis of infectious diseases

MRIGlobal today announced that it has been awarded a $14.8 million contract to develop an end-to-end next generation sequencing system for clinical diagnosis of infectious diseases.

23 Feb 2015

Finding opens avenues of research toward precision treatments to boost life expectancy for CF patients

Mutation of one gene is all it takes to get cystic fibrosis (CF), but disease severity depends on many other genes and proteins. For the first time, researchers at the UNC School of Medicine have identified genetic pathways - or clusters of genes - that play major roles in why one person with CF might never experience the worse kinds of symptoms while another person will battle severe airway infection for a lifetime.

23 Feb 2015

Researcher uses Gene Rank technique to capture, describe gene connectivity

Using the technique known as "Gene Rank" (GR), Dartmouth's Norris Cotton Cancer Center investigator Eugene Demidenko, PhD, captured and described a new characterization of gene connectivity in "Microarray Enriched Gene Rank," published in BioData Mining. The effective computer algorithm can be used to compare tissues across or within organisms at great speed with a simple laptop computer.

15 Feb 2015

Research report on global market for cell-based assays

BioInformatics LLC has announced the release of their latest report, The Market for Cell-Based Assays.

13 Feb 2015

IGI Global publishes bioinformatics book authored by Waynesburg University Professor

IGI Global, an international publishing company of progressive academic research, books and journals, recently accepted and published the literary works of Waynesburg University associate professor of computer science Dr. Elizabeth Wang.

13 Feb 2015

New study indicates that malaria-causing parasite is unlikely to cross from animals to humans

In recent years, public health experts have increasingly explored the idea of eliminating the most dangerous malaria-causing parasite. But they have questioned whether getting rid of this species, called Plasmodium falciparum, would allow other species of the parasite to simply jump into the gap and start infecting humans with malaria.

13 Feb 2015

Bioinformatics News and Research

Further Reading

Fecal microbiota transplantation more successful for treating Clostridium difficile infections

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

New study reveals how cells sort out loops meant to encode microRNAs

Key finding may point to immediate cause of CF exacerbations

TGAC plans to use miniaturised sequencing device to conduct live environmental surveillance

Los Alamos scientists develop new method for metagenomic analysis

GenomeNext completes whole genome sequencing analysis at unprecedented 1,000 genomes per day

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

Study: Listening to classical music improves activity of genes involved in brain functions

Research findings offer new insights into pathophysiology of PTSD

New tool provides molecular details about how mutations affect cellular processes

Beckman Coulter Genomics Introduces a Scalable RNA-seq service line for processing intact and degraded RNA samples

Researchers find that new targeted drugs can attack weak spots in cancer cells

Agena releases MassARRAY 24-Well System for mass spectrometry-based genetic testing

MRIGlobal awarded contract to develop Sample-to-Sequence system for diagnosis of infectious diseases

Finding opens avenues of research toward precision treatments to boost life expectancy for CF patients

Researcher uses Gene Rank technique to capture, describe gene connectivity

Research report on global market for cell-based assays

IGI Global publishes bioinformatics book authored by Waynesburg University Professor

New study indicates that malaria-causing parasite is unlikely to cross from animals to humans

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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