Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of the tumors themselves, according to new research led by NYU Langone Health and its Perlmutter Cancer Center.

8 Nov 2023

Simultaneous inhibition of two proteins may be a new strategy for tackling triple-negative breast cancer

Researchers at the Centre for Genomic Regulation and Vall d'Hebron Institute of Oncology have shown that the simultaneous inhibition of two different proteins may represent a new strategy for tackling triple-negative breast cancer, the most aggressive and drug-resistant form of breast cancer.

8 Nov 2023

Reversing biological age could increase longevity and lower dementia and stroke risk

The association between three clinical BA measures and neurological disease risk.

8 Nov 2023

Study validates first-in-class AI-driven digital pathology colorectal cancer diagnostic tool

In a peer-reviewed study published today in Nature Communications, a team of scientists from French-American techbio Owkin and pathology labs in France present a blind validation of MSIntuit CRC, a first-in-class AI-driven digital pathology diagnostic developed by Owkin, as a pre-screening tool aimed at optimizing the precision of diagnosis and treatment of colorectal cancer.

7 Nov 2023

Enhanc3D Genomics expands leadership team with the appointment of Hazel Jones as Chief Operating Officer

Enhanc3D Genomics today announced the appointment of Hazel Jones as Chief Operating Officer.

6 Nov 2023

Blood test predicts MS disability worsening up to two years in advance

Multiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability one to two years later, according to a new study spearheaded by researchers at UC San Francisco.

6 Nov 2023

High biological age linked to increased risk of stroke and dementia

People who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, especially vascular dementia.

6 Nov 2023

Avocado a day may keep diabetes at bay, suggests nutritional biomarker study

New research in The Journal of Nutrition links avocado consumption with lower diabetes risk, revealing specific metabolomic biomarkers that indicate potential for reduced fasting glucose and insulin levels.

5 Nov 2023

Life's hardships rewire the brain: Study pinpoints neural changes from adversity

Research reveals that adverse life experiences heighten amygdala response and diminish prefrontal cortex activity, indicating potential neural mechanisms of psychological vulnerability.

5 Nov 2023

Urinary biomarkers can show enhanced performance than plasma biomarkers in disease detection

In recent decades, the emphasis of biomarker research has centered around blood-based markers.

2 Nov 2023

Biomarker discovery boosts long-COVID prediction accuracy to 78.5%

Researchers identify four critical biomarkers associated with long-COVID, offering a 78.5% accuracy in predicting the condition. This discovery paves the way for diagnostic tests and offers insights into the mechanisms of persistent post-COVID symptoms.

1 Nov 2023

Highly sensitive blood test shows promise for early detection of common deadly cancers

Most cancers become deadly by keeping a low profile, causing no symptoms until they're too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses.

1 Nov 2023

New study provides insights about mosaic chromosomal alterations in diverse populations

As people age, the DNA in their cells begins to accumulate genetic mutations. Mosaic chromosomal alterations (mCAs), a category of mutations acquired in blood cells, are linked with a 10-fold increased risk of developing blood cancer.

1 Nov 2023

Clinical trial demonstrates the effectiveness of ALS drug in treating people with acute spinal cord injuries

A small clinical trial with a pharmacokinetic sub-study, led by a world-renowned pharmacologist at the University of Houston, has demonstrated the promising effectiveness of the drug Riluzole for improving functionality in people with acute spinal cord injuries (SCI) if the drug is taken within 12 hours post-injury.

1 Nov 2023

Study finds epigenetic signature for obesity susceptibility in human twins

A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.

1 Nov 2023

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Researchers aimed to identify dependable protein biomarkers for multiple sclerosis (MS).

1 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

IU researchers play key roles in national consortium to study the use of Alzheimer's disease biomarkers

Researchers at Indiana University School of Medicine will play key roles in a national consortium led by Wake Forest University School of Medicine to study the use, interpretation and implementation of biomarkers to diagnose Alzheimer's disease.

27 Oct 2023

Biomarker News and Research

Further Reading

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Gamma delta T cells engineered to be more potent and long-lasting against cancer

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Simultaneous inhibition of two proteins may be a new strategy for tackling triple-negative breast cancer

Reversing biological age could increase longevity and lower dementia and stroke risk

Study validates first-in-class AI-driven digital pathology colorectal cancer diagnostic tool

Enhanc3D Genomics expands leadership team with the appointment of Hazel Jones as Chief Operating Officer

Blood test predicts MS disability worsening up to two years in advance

High biological age linked to increased risk of stroke and dementia

Avocado a day may keep diabetes at bay, suggests nutritional biomarker study

Life's hardships rewire the brain: Study pinpoints neural changes from adversity

Urinary biomarkers can show enhanced performance than plasma biomarkers in disease detection

Biomarker discovery boosts long-COVID prediction accuracy to 78.5%

Highly sensitive blood test shows promise for early detection of common deadly cancers

New study provides insights about mosaic chromosomal alterations in diverse populations

Clinical trial demonstrates the effectiveness of ALS drug in treating people with acute spinal cord injuries

Study finds epigenetic signature for obesity susceptibility in human twins

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

How one gene shakes up our understanding of male infertility

IU researchers play key roles in national consortium to study the use of Alzheimer's disease biomarkers

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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