Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Biological markers for triple-negative breast cancer (TNBC): an interview with Alexandre Templier, CEO of Quinten

Triple negative breast cancer (TNBC) is a type of cancer that has none of the three markers that are currently used for targeted chemotherapy. These markers are estrogen receptor (ER), progesterone receptor (PR) and HER2.

27 Mar 2013

Depression also diminish health benefits of physical activities, say researchers

Depression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine.

27 Mar 2013

Study shows vitamin D can help people breathe better and protect against TB

Maintaining adequate levels of vitamin D can help people breathe better and may even protect against tuberculosis (TB), according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

26 Mar 2013

Migraines are related to brain abnormalities, new study suggests

A new study suggests that migraines are related to brain abnormalities present at birth and others that develop over time.

26 Mar 2013

Atrophy of thalamus is important predictor of clinically definite MS, study shows

A growing body of research by multiple sclerosis investigators at the University at Buffalo and international partners is providing powerful new evidence that the brain's gray matter reflects important changes in the disease that could allow clinicians to diagnose earlier and to better monitor and predict how the disease will progress.

22 Mar 2013

Common test may overestimate exposure to mercury vapor from dental amalgams

A common test used to determine mercury exposure from dental amalgam fillings may significantly overestimate the amount of the toxic metal released from fillings, according to University of Michigan researchers.

21 Mar 2013

TSRI receives fund to develop new field test for Onchocerciasis

Philanthropist, businessman and community leader John Moores has given The Scripps Research Institute approximately $2 million to fund the development of a new field test for Onchocerciasis, or river blindness, a parasitic infection that affects tens of millions of people in Africa, Latin America and other tropical regions.

21 Mar 2013

Dementia diagnostic panel for treatable forms of cognitive impairment launched by Quest Diagnostics

Quest Diagnostics (NYSE: DGX), the world’s leading provider of diagnostic information services, announced the availability of the first clinical test panel for aiding the diagnosis of suspected dementia due to treatable forms of cognitive impairment. The test panel is believed to be the first commercial service from a clinical laboratory to combine several guideline-recommended tests for identifying secondary, treatable causes of dementia as a single blood test and report.

From Quest Diagnostics 19 Mar 2013

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

Alnylam Pharmaceuticals a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-TTRsc, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).

19 Mar 2013

Research reveals immortality gene mutation plays pivotal role in brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research led by Duke Cancer Institute.

19 Mar 2013

Migraine severity may be predicted by blood levels of fat cell hormone

In a small, preliminary study of regular migraine sufferers, scientists have found that measuring a fat-derived protein called adiponectin (ADP) before and after migraine treatment can accurately reveal which headache victims felt pain relief.

18 Mar 2013

Study reveals potential markers for treating patients with metastatic clear cell RCC

Markers such as CA9, CD31, CD34 and VEGFR1/2 in the primary tumours might serve as predictors of a good response to a sunitinib treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to a new study to be presented at the 28th Annual EAU Congress currently on-going in Milan.

18 Mar 2013

Study on neoadjuvant cisplatin-based chemotherapy presented at 28th Annual EAU Congress

At the 28th Annual EAU Congress currently ongoing in Milan until Tuesday, W. Tan and colleagues presented their study on neoadjuvant cisplatin-based chemotherapy which showed that epigenetic changes are potential key drivers in the development of chemo resistance in bladder cancer.

18 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Study shows improved detection of dementia paves the way for refined clinical trials testing

A series of studies demonstrate improved detection of the second most common form of dementia, providing diagnostic specificity that clears the way for refined clinical trials testing targeted treatments.

18 Mar 2013

Article explores benefits of innovative programs for personalized health care

Two innovative programs designed to improve the availability of emerging medical technologies that can help patients receive more effective, efficient and personalized health care are advanced in a commentary written by a team of scientists and policy experts, including seven from Arizona State University, and published today in Science Translational Medicine.

15 Mar 2013

Researchers develop single molecule test for detecting methylated DNA

Collaborators from Mayo-Illinois Alliance for Technology Based Healthcare have developed a new, single molecule test for detecting methylated DNA. Methylation -- the addition of a methyl group of molecules to a DNA strand -- is one of the ways gene expression is regulated.

15 Mar 2013

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

...

14 Mar 2013

Low T3 syndrome predicts adverse clinical outcomes and depressive symptoms

In a study of 90 patients undergoing surgery for brain tumor, researchers in Lithuania and the United States have discovered that the finding of low T3 (triiodothyronine) syndrome is predictive of unfavorable clinical outcomes and depressive symptoms.

14 Mar 2013

Post-discharge activity level linked to risk of hospital readmission in elderly

A new study has found a link between the activity levels of elderly people who have just been released from the hospital and the risk that they will require readmission within 30 days.

14 Mar 2013

Biomarker News and Research

Further Reading

Biological markers for triple-negative breast cancer (TNBC): an interview with Alexandre Templier, CEO of Quinten

Depression also diminish health benefits of physical activities, say researchers

Study shows vitamin D can help people breathe better and protect against TB

Migraines are related to brain abnormalities, new study suggests

Atrophy of thalamus is important predictor of clinically definite MS, study shows

Common test may overestimate exposure to mercury vapor from dental amalgams

TSRI receives fund to develop new field test for Onchocerciasis

Dementia diagnostic panel for treatable forms of cognitive impairment launched by Quest Diagnostics

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

Research reveals immortality gene mutation plays pivotal role in brain tumors, other cancers

Migraine severity may be predicted by blood levels of fat cell hormone

Study reveals potential markers for treating patients with metastatic clear cell RCC

Study on neoadjuvant cisplatin-based chemotherapy presented at 28th Annual EAU Congress

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Study shows improved detection of dementia paves the way for refined clinical trials testing

Article explores benefits of innovative programs for personalized health care

Researchers develop single molecule test for detecting methylated DNA

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

Low T3 syndrome predicts adverse clinical outcomes and depressive symptoms

Post-discharge activity level linked to risk of hospital readmission in elderly

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News