Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

The link between combined HRT use and the risk of lobular breast cancers

Postmenopausal women who take combined estrogen/progestin hormone-replacement therapy for three years or more face a fourfold increased risk of developing various forms of lobular breast cancer, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

15 Jan 2008

Metabolic syndrome in children

Metabolic syndrome in children represents a potentially serious threat to health in adulthood, yet many parents and caregivers do not have a clear idea of what metabolic syndrome is and why it is dangerous.

15 Jan 2008

Lymphangioleiomyomatosis - potential clues into the treatment and diagnosis

Studies published in the Jan. 10 edition of the New England Journal of Medicine (NEJM) are providing clues into the treatment and diagnosis of LAM, or lymphangioleiomyomatosis, a progressive and deadly lung disease that affects women in their childbearing years.

11 Jan 2008

Take care of your teeth and gums for a healthy heart

Each year, cardiovascular disease kills more Americans than cancer. And while most people are aware that lifestyle choices such as eating right, getting enough exercise and quitting smoking can help prevent cardiovascular disease, they may not know that by just brushing and flossing their teeth each day, they might also be avoiding this potentially lethal condition.

9 Jan 2008

New biomarker for predicting liver cancer spread and survival discovered

New research has shown that a unique pattern of microRNAs, small RNA molecules that regulate gene activity, can accurately predict whether liver cancer will spread and whether liver cancer patients will have shorter or longer survival, even patients with early stage disease.

7 Jan 2008

Regular brisk walking helps women cope with the menopause

Scientists in the U.S. say some of the symptoms of the menopause can be alleviated with regular exercise.

6 Jan 2008

NIEHS awards $6.8 million DISCOVER grants

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, is awarding a total of $6.8 million for the first year of funding to three new research centers called DISCOVER - Disease Investigation Through Specialized Clinically-Oriented Ventures in Environmental Research.

28 Dec 2007

Cancer stem cells may be at the root of brain tumors

Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer. Amongst the wildly dividing cells of a tumor, scientists have located cancer stem cells.

27 Dec 2007

FDA Critical Path Initiative addresses differences between women's and men's health outcomes

Advanced medical technology and analysis methods now being promoted through the Food and Drug Administration's Critical Path Initiative to facilitate the development of drugs, biologics and devices can help address differences between women and men in the detection and treatment of disease, according to a paper published in the Winter 2007 issue of Drug Discovery Today: Technologies.

20 Dec 2007

Study looks at prevalence of "false-positive" catheterization laboratory activation for patients with suspected STEMI

Physicians caring for patients suspected of having a heart attack may trigger "false-positive" activation of the cardiac catheterization laboratory based on test results suggestive of a heart attack, according to a study in the December 19 issue of JAMA: The Journal of the American Medical Association.

20 Dec 2007

Surprising findings related to myotonic muscular dystrophy and heart protein

New research from the University of Virginia Health System shows that, in cases of Type 1 myotonic muscular dystrophy (DM1), a well known heart protein does several surprising things.

18 Dec 2007

New findings on myotonic muscular dystrophy

New research from the University of Virginia Health System shows that, in cases of Type 1 myotonic muscular dystrophy (DM1), a well known heart protein does several surprising things. DM1 is the most common form of muscular dystrophy in adults and affects approximately 40,000 adults and children in the U.S.

18 Dec 2007

Medical College of Georgia selected as RNA laboratory for worldwide diabetes study

The Medical College of Georgia Center for Biotechnology and Genomic Medicine has been selected to isolate RNA and DNA from the blood of thousands of children involved in a worldwide study of the causes of type 1 diabetes.

18 Dec 2007

Corgenix Medical enters development agreement wth NIH

Corgenix Medical Corporation has announced it has entered into a corporative research and development agreement (CRADA) with the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH).

18 Dec 2007

Direct link between obesity and colorectal cancer

A clear, direct link between obesity and colorectal cancer, the second most common form of cancer in Australia with more than 12,000 new cases each year, has been shown in a new analysis by The George Institute for International Health in Sydney, Australia.

17 Dec 2007

Novel way to diagnose mantle cell lymphomas

Mantle cell lymphoma is an aggressive form of blood cancer that most commonly afflicts older men.

13 Dec 2007

Epigenomic test that could improve treatment for specific gastric cancers

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center in a recent issue of Journal of Clinical Oncology identifies activation of the enzyme COX-2 in gastric cancer tumors as a prognostic indicator for poor outcome.

12 Dec 2007

Missing protein provides clue to ovarian cancer drug success

Scientists have discovered a protein which could improve the success rate of the tumour shrinking drug paclitaxel, in the treatment of ovarian cancer, a study reveals in Cancer Cell.

10 Dec 2007

Explanation on resistance to taxane class of drugs

Scientists have uncovered critical new details about the mechanisms that modulate the response of ovarian cancer cells to chemotherapy.

10 Dec 2007

Calcium in coronary arteries may be linked to increased risk for heart disease in low-risk women

About 5 percent of women considered low-risk for heart disease by current classification standards have evidence of advanced coronary artery calcium and may be at increased risk for cardiovascular events, according to a report in the December 10/24 issue of Archives of Internal Medicine.

10 Dec 2007