Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Health Discovery receives notice of allowance of U.S. patent application covering kernel selection methods

Health Discovery Corporation has announced that the U.S. Patent and Trademark Office has issued a notice of allowance of HDC's patent application covering methods for selection of kernels, i.e., functions or algorithms that are used to transform input data into a different configuration, known as "feature space", which allows for easier recognition of patterns within the data.

18 Oct 2007

Sugars, not proteins make bones tough

Researchers have discovered that the structure of human bones is vastly different than previously believed - findings which will have implications for how some debilitating bone disorders are treated.

17 Oct 2007

New knowledge about basic cancer biology

Merging technological innovations and new knowledge about basic cancer biology, cancer researchers now target specific molecules involved in critical chemical pathways of cancerous cells.

17 Oct 2007

New insight into Herceptin resistance in breast cancer

A new study provides important insight into the mechanisms involved in resistance to treatment of breast cancer patients with trastuzumab (Herceptin). The research, published by Cell Press in the October issue of the journal Cancer Cell , identifies markers that may help to identify patients who are unlikely to respond to trastuzumab treatment and provides a potential strategy for treating these patients.

16 Oct 2007

Hooked on chocolate? the answer why may lie in your gut

For the first time, scientists have linked the all-too-human preference for a food - chocolate - to a specific, chemical signature that may be programmed into the metabolic system and is detectable by laboratory tests.

15 Oct 2007

Arsenic exposure during pregnancy linked to low-birth-weight infants

Bangladeshi women exposed to high levels of arsenic during pregnancy are at increased risk of having a low-birth-weight infant, reports a study in the October Journal of Occupational and Environmental Medicine , official publication of the American College of Occupational and Environmental Medicine (ACOEM).

15 Oct 2007

Biopharmaceutical infrastructure key to lower drug development costs

Improvements to the technology infrastructure for researching and developing new biopharmaceuticals would be expected to save the industry hundreds of millions of dollars annually, according to a new economic study sponsored by the National Institute of Standards and Technology (NIST).

12 Oct 2007

Cancer researchers investigate free radicals

The University of Leicester has been selected as the hub of a worldwide network of researchers to investigate one of the causes of cancer.

11 Oct 2007

African-American men have a slightly higher risk of PSA recurrence

African-American men are more likely to have their prostate cancer return after treatment, but their disease is no more aggressive when it does recur than that of their white counterparts, according to a study led by Duke Prostate Center researchers.

10 Oct 2007

HAART stops brain damage caused by HIV

A combination of drugs widely used to treat infections caused by HIV appears to stop brain damage caused by the virus as well, according to a study published in the October 9, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

9 Oct 2007

What our genes tell us - Identifying biomarkers for key environmental risk factors

Identifying biomarkers for the key environmental risk factors responsible for two diseases that significantly contribute to death and disease of hundreds of thousands annually will be the initial focus of a new center being established at Pacific Northwest National Laboratory.

4 Oct 2007

Ovarian Cancer Biomarker Research Act of 2007 introduced

The Ovarian Cancer Biomarker Research Act of 2007 was introduced in the U.S. House of Representatives on Thursday, Sept. 27 and the Society of Gynecologic Oncologists (SGO), the leader of four organizations integral in drafting this legislation, is issuing a "call to action" for ovarian cancer survivors, their families, and their physicians.

3 Oct 2007

Defining biomarkers for better colon cancer treatment

Barcelona, Spain: New research has yielded a clearer picture of which biomarkers could help doctors more precisely target the treatment of colon cancer, bringing closer the day when patients who will not benefit from chemotherapy are spared it, while those that will, get the more aggressive treatment they need.

27 Sep 2007

Sandia develops portable microfluidic platform to detect biotoxins

Of all the threat scenarios facing emergency responders around the country, the release and spread of a dangerous biotoxin in a large public space is one of the most troubling.

27 Sep 2007

A blood test for concussions - aim of new research

The University of Rochester Medical Center received $1.5 million to develop a blood test for concussions by isolating proteins that can predict memory loss, chronic headaches or other neurological problems.

26 Sep 2007

Discovery of two new proteins associated with colorectal cancer

Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma.

25 Sep 2007

Prana completes enrolment in phase IIa trial of PBT2 in Alzheimer's disease patients

Prana Biotechnology Limited today announced it has completed patient enrollment in its Phase IIa clinical trial of PBT2 in patients with early Alzheimer's disease.

24 Sep 2007

Past clinical trials of vitamin E fatally flawed

Generations of studies on vitamin E may be largely meaningless, scientists say, because new research has demonstrated that the levels of this micronutrient necessary to reduce oxidative stress are far higher than those that have been commonly used in clinical trials.

24 Sep 2007

Growth hormone does not improve physical performance

Anyone who injects growth hormone with the intention of gaining muscle mass and improving performance should think again.

24 Sep 2007

Framingham Heart Study 100K result published

BioMed Central has announced that 17 research articles carried out using genetic data from the Framingham Heart Study (FHS), are being published as a supplement to BMC Medical Genetics.

23 Sep 2007