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Glyoxalase I protects proteins against damage by oxidation and nitration

Protein degradation and malfunction is a major cause of ageing and can be the result of attacks on proteins by other molecules.

2 Apr 2007

Coronary procedure adds no benefit over 'optimal medical therapy' alone

Percutaneous coronary intervention plus optimal medical therapy does not improve outcomes in patients with coronary artery disease, compared with optimal medical therapy alone, according to study results presented at the 56th Annual Scientific Session of the American College of Cardiology in New Orleans, and published online in the New England Journal of Medicine.

1 Apr 2007

New cardiovascular treatment approaches

In an era of increasing death and illness from heart and blood vessel disease - which also can impair kidney function - Mayo Clinic researchers have designed two promising new cardiovascular treatment approaches.

30 Mar 2007

The need for a bronzed glow could be in the genes

Researchers have found that a gene which helps to control tumours also triggers the chemical chain reaction that makes the skin tan when exposed to ultraviolet (UV) light.

12 Mar 2007

Computer key unlocks cancer, multiple sclerosis, and Alzheimer's disease

Danish and Belgian researchers have found a computer key that maps genes underlying heritable disorders, such as breast cancer, multiple sclerosis, and Alzheimer's disease. These results will possibly ease the discovery of new medicines and improve treatment in various disorders.

8 Mar 2007

Gene that prevents cancer also controls the skin's suntanning machinery

"The p53 tumor suppressor is commonly mutated in human cancer," explained David Fisher, director of the Melanoma Program in Medical Oncology at Dana-Farber Cancer Institute. "Now, we've found that it plays a role in the skin's tanning response."

8 Mar 2007

Bold proposal to restructure drug development patents

Weill Cornell Medical College scientist Dr. Carl Nathan has issued a bold call for reforming the pharmaceutical development and patent systems in order to increase the number of vaccines and drugs available to combat neglected diseases that are ravaging the world's poor.

8 Mar 2007

Life-saving cancer genetic testing vastly underutilized

A study released today at the Society of Gynecologic Oncologists 38th Annual Meeting on Women's Cancer found few patients were aware of genetic cancer syndromes and the high risk of developing cancer if genetic mutations were found. Fewer still were motivated to follow up on this information with their own healthcare provider or genetic counseling/testing services.

5 Mar 2007

British Government to ask public what they think of stem cell science

Britain's Science and Innovation Minister Malcolm Wicks has announced that the UK's two major public funders of stem cell research will run a national public discussion about this cutting-edge area of science.

1 Mar 2007

Entire genetic blueprints of more than 2,000 human and avian influenza viruses completed and made public

The Influenza Genome Sequencing Project, funded by the National Institute of Allergy and Infectious Diseases (NIAID), announced today that it has achieved a major milestone.

21 Feb 2007

Legislation introduced that would give FDA authority to approve generic versions of biotechnology drugs

Lawmakers in the House and Senate on Wednesday introduced a bill that would allow FDA to approve generic versions of biotechnology medications, USA Today reports.

19 Feb 2007

Health care industry groups lobby Presidential candidates

Roll Call on Wednesday examined how health care is "quickly becoming a cornerstone" of 2008 presidential candidates' domestic proposals and how "health industry groups and their lobbyists already are trying to make sure candidates in both parties keep their interests in mind along the campaign trail."

19 Feb 2007

Horse genome sequence assembled

The first draft of the horse genome sequence has been deposited in public databases and is freely available for use by biomedical and veterinary researchers around the globe, leaders of the international Horse Genome Sequencing Project announced today.

7 Feb 2007

WHO cautions Thailand against issuing compulsory license for antiretroviral Kaletra

The World Health Organization on Thursday cautioned the Thai government on its decision to allow the country to produce a lower-cost version of Abbott Laboratories' antiretroviral drug Kaletra by granting a compulsory license for the drug, the Bangkok Post reports.

7 Feb 2007

Human proteins evolving slowly thanks to multi-tasking genes

Many human proteins are not as good as they might be because the gene sequences that code for them have a double role which slows down the rate at which they evolve, according to new research published in PLoS Biology.

6 Feb 2007

Corn, oats, cherries and red wine's high melatonin content can help delay ageing

The Spanish Ageing Research Network (Red Nacional de Investigación del Envejecimiento), funded by Carlos III Health Institute and headed by professor Darío Acuna Castroviejo, from the University of Granada, is very near to achieving one of today's Science greatest goals: allowing humans to age in the best possible health conditions.

31 Jan 2007

New drug to treat kidney failure during septic shock

Research from Melbourne's Howard Florey Institute and the Austin Hospital has resulted in a drug to treat kidney failure during septic shock, which will be trialled at the Austin Hospital from mid-2007.

29 Jan 2007

New understanding of the hit-and-run tactics used by infectious bacteria

New research from scientists at the University of Cambridge has the potential to radically change our understanding of how infection spreads around the body and improve the methods used to control it.

22 Jan 2007

Shire licenses the north American rights for Apricitabine to Avexa

Shire plc has announced that it licensed the North America (U.S. and Canada) rights for the investigational HIV compound, SPD754 (also known as apricitabine), to the Australian biotechnology company Avexa Limited in return for an up-front payment of US$10 million, development and sales related milestones and royalties.

22 Jan 2007

Lessons from Vioxx litigation

The pharmaceutical industry, academia and government agencies need to work together to restore faith in drug development, say doctors in this weeks' British Medical Journal.

18 Jan 2007