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Tantalizing glimmers about roles of CCR2 gene, Th17 cell and a missing monocyte

An estimated 1.3 million people in the United States suffer from rheumatoid arthritis. The causes behind this chronic disease — which can exhibit itself as pain, swelling, stiffness, deformation, and loss of function in the joints — have eluded scientists for centuries. A new study by UNC researchers offers tantalizing glimmers about the roles of a gene called CCR2, an immune system cell called Th17 cell, and a missing monocyte.

11 Oct 2011

New mechanism to enhance restoration of blood flow in ischemic diseases

In Nature, VIB-K.U.Leuven researchers describe a new mechanism to enhance the restoration of the blood flow in ischemic diseases, which are among the leading causes of death worldwide.

11 Oct 2011

Middle-aged woman with RLS more likely to develop hypertension

If you're a middle-aged woman with Restless Legs Syndrome, you may have a higher risk of developing high blood pressure, according to new research reported in Hypertension: Journal of the American Heart Association.

11 Oct 2011

Statins hold promise against traumatic brain injury

Older patients who happened to have been taking cholesterol-lowering statin drugs when admitted to the hospital with serious head injuries were 76 percent more likely to survive than those not taking the drugs, according to results of a Johns Hopkins study.

11 Oct 2011

LUGPA encourages men to speak out to preserve prostate cancer screenings

The Large Urology Group Practice Association (LUGPA), representing more than 1,800 urologists, encourages men to speak out to preserve prostate cancer screenings.

11 Oct 2011

New DCE-CT technique gives better clues to future cardiac events in heart patients

A new non-invasive technique for measuring how well the heart and blood vessels function in patients already suffering from coronary artery disease could, in a single test, identify which abnormally narrowed blood vessels are the most likely to lead to further cardiovascular complications.

11 Oct 2011

Simple test can save lives of infants with undiagnosed critical heart defects

The US Secretary of Health recently supported a recommendation that all babies born in the US are to be screened for critical heart defects, before leaving hospital. Behind this decision is a study from the Sahlgrenska Academy at the University of Gothenburg, and the West Götaland Region's maternity units in Sweden which shows that a simple test can save the lives of newborns with these heart defects.

11 Oct 2011

Positive results from Biotron's BIT225 Phase 2a trial on HCV

Australian drug development company Biotron Limited has released headline results from its landmark Phase 2a trial of its lead drug candidate, BIT225 in Hepatitis C virus (HCV) infected patients.

11 Oct 2011

Rare and severe hypoglycemia could be genetic

The life-threatening condition depicts the fact that the body does not have enough energy to function. Scientists at the University of Cambridge say mutations in the AKT2 gene are to blame. Writing in the journal Science, they say there are already cancer drugs which target a similar process.

10 Oct 2011

Merck’s diabetes combo pill gets FDA nod

The U.S. Food and Drug Administration (FDA) has approved Merck & Co.’s Juvisync diabetes drug, a combination pill for type 2 diabetes. Juvisync combines two Merck drugs already on the market, 1) glucose-lowering Januvia (Sitagliptin) medication and 2) cholesterol-lowering Zocor (Simvastatin).

10 Oct 2011

AIT Laboratories introduces new suite of services for prescription compliance monitoring

Chronic pain affects an estimated 116 million adults in the U.S.—more than the number affected by heart disease, diabetes, and cancer combined, according to a recent report by the Institute of Medicine.

10 Oct 2011

Scientists identify first DNA faults linked to melanoma

Cancer Research UK scientists have discovered the first DNA faults linked to melanoma - the deadliest skin cancer - that are not related to hair, skin or eye colour, according to research published in Nature Genetics today.

10 Oct 2011

New siRNA treatment reduces damaging inflammation in animals models of several disorders

Massachusetts General Hospital (MGH) researchers - along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals - have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions.

10 Oct 2011

Researchers focus on gelatinase inhibitor compounds to treat neurological diseases

Results of a study by a group of University of Notre Dame researchers represent a promising step on the road to developing new drugs for a variety of neurological diseases.

10 Oct 2011

Advocates prepare for battle on PSA testing; insurers review options

A day after a government panel said that healthy men should no longer get screened for prostate cancer, some doctors' groups and cancer patients' advocates began a campaign to convince the nation that the advice was misguided. Their hope is to copy the success of women's groups that successfully persuaded much of the country two years ago that it was a mistake for the same panel, the United States Preventive Services Task Force, to recommend against routine mammograms for women in their 40s.

10 Oct 2011

Merck receives FDA approval for JUVISYNC to treat type 2 diabetes

Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved JUVISYNC(sitagliptin and simvastatin), a new treatment for type 2 diabetes that combines the glucose-lowering medication sitagliptin, the active component of JANUVIA (sitagliptin), with the cholesterol-lowering medication ZOCOR.

10 Oct 2011

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases.

10 Oct 2011

Study identifies gene mutation responsible for higher frequency of Italian CDA II

Many of you might know that Congenital Dyserythropoietic Anemia type II (CDA II) is a rare blood disorder, due to a failure in final part of erythropoiesis. What will surprise you is the fact that some mutations responsible for the disease can be tracked 3.000 years back.

10 Oct 2011

Loyola surgeon performs minimally invasive emergency procedure to repair AAA

Jack Kory of Mokena, Il. was eating his breakfast oatmeal when he suddenly felt the worst pain in his life. The searing pain came on suddenly in his stomach and spread to his knees. It was caused by an abdominal aortic aneurysm (AAA) that had suddenly burst, causing massive internal bleeding. Traditionally, few patients have survived such ruptures. But Loyola University Medical Center vascular surgeon Dr. Richard Hershberger was able to repair Kory's aneurysm with a minimally invasive emergency procedure.

10 Oct 2011

UMass Amherst SPHHS wins HHS award to create Public Health Training Center

Training to improve the nation's public health system by strengthening the technical, scientific, managerial and leadership competence of current and future public health workers will soon be underway in Springfield, Holyoke, Pittsfield and the Berkshires, supported by a four-year, $2.5 million grant to the School of Public Health and Health Sciences (SPHHS) at the University of Massachusetts Amherst.

10 Oct 2011