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Discovery of cancer drugs to kill malaria parasite could open up new strategies for treatment

Ahead of World Malaria Day (25 April), EU-funded researchers have discovered that drugs originally designed to inhibit the growth of cancer cells can also kill the parasite that causes malaria. They believe this discovery could open up a new strategy for combating this deadly disease, which, according to World Health Organisation statistics, infected around 225 million and killed nearly 800 000 people worldwide in 2009.

21 Apr 2011

First UCLA patient with hand transplant doing well at six-and-a-half weeks

Six-and-a-half weeks after receiving the first hand transplant in the western United States, Emily Fennell is becoming so accustomed to her new right hand that she barely remembers when she didn't have one.

21 Apr 2011

First Edition: April 21, 2011

In today's news, reports about President Barack Obama's Facebook visit during which he stepped up his criticism of GOP plans to overhaul Medicare and Medicaid but said he expects to strike a deal to reduce the deficit.

21 Apr 2011

NEJM features pulse oximetry training video

A pulse oximetry training video produced by Rafael Ortega, MD, the vice-chair of academic affairs for the department of anesthesiology at Boston Medical Center (BMC) and professor of anesthesiology at Boston University School of Medicine (BUSM), and his colleagues is featured in this week's New England Journal of Medicine.

21 Apr 2011

Scientists explore the role of microRNA that influences obesity-related traits

Eating more n-3 polyunsaturated fatty acids, commonly known as omega-3 fatty acids, may help carriers of a genetic variant on the perilipin 4 (PLIN4) gene locus lose weight more efficiently.

21 Apr 2011

Alexion first quarter non-GAAP net income increases to $56.3 million

Alexion Pharmaceuticals, Inc. today announced financial results for the three months ended March 31, 2011. Alexion Pharmaceuticals, Inc. reported net product sales of Soliris® (eculizumab) of $166.1 million, reflecting steady additions of new patients, compared to $117.6 million for the same period in 2010.

21 Apr 2011

Jennerex and Green Cross report positive phase 2 JX-594 clinical trial for liver cancer

Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic products for cancer, and Green Cross Corporation, a leading company in the development, manufacturing, and commercialization of viral vaccines and other biological products, today reported positive clinical data from a Phase 2 trial evaluating JX-594 for liver cancer which was conducted in South Korea.

21 Apr 2011

Sedentary lifestyle in childhood narrows vessels in the retina and increases risk of cardiovascular disease

Six-year-olds who spent the most time watching television, using a computer or playing video games had narrower arteries in the back of their eyes — a marker of future cardiovascular risk, in a first-of-its-kind study reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

21 Apr 2011

KellBenx secures $2.5 million from initial funding round

KellBenx, a biotechnology company focused on the development of non-invasive prenatal diagnosis (NIPD) of genetic and inherited disorders, announced today that it has secured an initial funding round of $2.5 million from four investors – three biotechnology venture capital groups and one angel investor. The round will finance a clinical trial and laboratory testing of a new, minimally invasive blood test designed to identify risks to pregnancy ranging from pre-term birth to genetic conditions.

21 Apr 2011

Antenatal infection and ventilation with BPD associated with excessive accumulation of dendritic cells in lungs

Rates of premature births have increased in recent years, affecting more than 12% of all births and making strategies for managing the associated perinatal complications an important public goal. Preterm infants are particularly at risk for bronchopulmonary dysplasia (BPD), a chronic lung disease. BPD has multiple causes, and uncovering critical interactions within the immune system can lead to new approaches for treatment.

21 Apr 2011

Humans have three different gut types, finds study

In the future, when you walk into a doctor's surgery or hospital, you could be asked not just about your allergies and blood group, but also about your gut type. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and collaborators in the international MetaHIT consortium, have found that humans have 3 different gut types.

21 Apr 2011

Ketogenic diet may reverse impaired kidney function in diabetics

Researchers from Mount Sinai School of Medicine have for the first time determined that the ketogenic diet, a specialized high-fat, low carbohydrate diet, may reverse impaired kidney function in people with Type 1 and Type 2 diabetes. They also identified a previously unreported panel of genes associated with diabetes-related kidney failure, whose expression was reversed by the diet. The findings were published in the current issue of PLoS ONE.

21 Apr 2011

Study finds ACE inhibitors linked to increased risk of recurrence in women who have had breast cancer

ACE inhibitors, commonly used to control high blood pressure and heart failure in women, may be associated with an increased risk of recurrence in women who have had breast cancer, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

21 Apr 2011

Genes linked to obesity may also cause poor weight loss outcomes after gastric bypass surgery

Researchers at Geisinger Health System are studying how genes may affect a patient's ability to lose weight following bariatric surgery. Highlighted in the journal Obesity, the study found that several genes that promote obesity may also result in inferior weight loss outcomes after gastric bypass surgery.

21 Apr 2011

Salix Pharmaceuticals receives three U.S. patents relating to rifaximin

Salix Pharmaceuticals, Ltd. today announced that the U.S. Patent and Trademark Office has issued three patents relating to rifaximin.

21 Apr 2011

New trial in UK to test whether statins could be used to treat pre-eclampsia

Pregnant women could benefit from a pioneering trial that will test whether heart disease drugs can be used to treat pre-eclampsia.

21 Apr 2011

NIH funds Rice University study of new materials for growing replacement heart valves

A team of bioengineers from Rice University is bringing a promising new strategy for growing replacement heart valves closer to reality, thanks to a four-year, $1.2 million grant from the National Institutes of Health. The team hopes to use gel-like materials to generate three-dimensional patterns called scaffolds that can simultaneously mimic the complex structural and physical properties of heart-valve tissues and guide the behavior of tissue-forming cells.

21 Apr 2011

Immigrant screening fails to detect more than 70% cases of latent tuberculosis infection

Current UK procedures to screen new immigrants for tuberculosis (TB) fail to detect more than 70 per cent of cases of latent infection, according to a new study published in The Lancet Infectious Diseases.

21 Apr 2011

Cancer Centers of North Carolina buys WROS from Wake Radiology

Cancer Centers of North Carolina (CCNC), an affiliate of the United Network of US Oncology and the first practice to offer community-based outpatient cancer care in the Triangle with locations in Raleigh, North Raleigh, Cary, Dunn and Clayton, has purchased Wake Radiology Oncology Services (WROS) from Wake Radiology, the oldest and largest multi-site radiology group in central North Carolina.

21 Apr 2011

Harvest initiates enrollment in trial of BMAC autologous cell composition to treat Congestive Heart Failure

Harvest Technologies Corp. announced today that the first twelve patients of its sixty patient Heart Failure trial have been enrolled at Medanta-the Medicity in Gurgaon INDIA.

21 Apr 2011

Blood News and Research

Discovery of cancer drugs to kill malaria parasite could open up new strategies for treatment

First UCLA patient with hand transplant doing well at six-and-a-half weeks

First Edition: April 21, 2011

NEJM features pulse oximetry training video

Scientists explore the role of microRNA that influences obesity-related traits

Alexion first quarter non-GAAP net income increases to $56.3 million

Jennerex and Green Cross report positive phase 2 JX-594 clinical trial for liver cancer

Sedentary lifestyle in childhood narrows vessels in the retina and increases risk of cardiovascular disease

KellBenx secures $2.5 million from initial funding round

Antenatal infection and ventilation with BPD associated with excessive accumulation of dendritic cells in lungs

Humans have three different gut types, finds study

Ketogenic diet may reverse impaired kidney function in diabetics

Study finds ACE inhibitors linked to increased risk of recurrence in women who have had breast cancer

Genes linked to obesity may also cause poor weight loss outcomes after gastric bypass surgery

Salix Pharmaceuticals receives three U.S. patents relating to rifaximin

New trial in UK to test whether statins could be used to treat pre-eclampsia

NIH funds Rice University study of new materials for growing replacement heart valves

Immigrant screening fails to detect more than 70% cases of latent tuberculosis infection

Cancer Centers of North Carolina buys WROS from Wake Radiology

Harvest initiates enrollment in trial of BMAC autologous cell composition to treat Congestive Heart Failure

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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