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Urologists say don’t give up on prostate cancer screening just yet

What's a guy to do? While prostate specific antigen (PSA) testing has been the standard screening tool for prostate cancer for several decades, results of a study recently published in The New England Journal of Medicine question the effectiveness of PSA screening in reducing death from prostate cancer. But many urologists argue that men should not be swayed from getting the test-it still saves lives.

13 May 2009

American Civil Liberties Union challenges breast cancer gene patents

The American Civil Liberties Union and the Public Patent Foundation at Benjamin N. Cardozo School of Law (PUBPAT) filed a lawsuit today charging that patents on two human genes associated with breast and ovarian cancer stifle research that could lead to cures and limit women's options regarding their medical care.

12 May 2009

High levels of estradiol hormone in men with heart failure linked to increased risk of death

Men with systolic chronic heart failure who have low or high levels of estradiol, a form of the hormone estrogen, have an increased risk of death compared with men with moderate levels of this hormone, according to a study in the May 13 issue of JAMA, the Journal of the American Medical Association.

12 May 2009

Research looks at advanced radiation therapy technique for pancreatic cancer

According to the American Cancer Society, pancreatic cancer is the fourth leading cancer killer in the country, with more than 42,000 new cases expected to be diagnosed this year and more than 35,000 deaths. In New Jersey alone, 1,000 deaths are estimated from the disease, which only has a five-year, five-percent survival rate.

12 May 2009

Formaldehyde exposure among industrial workers linked to greater risk of cancers of the blood and lymphatic system

Results from an ongoing study of workers employed at plants that used or produced formaldehyde continue to show a possible link between formaldehyde exposure and death from cancers of the blood and lymphatic system, particularly myeloid leukemia.

12 May 2009

Schering-Plough starts patient enrollment in phase 3 trial for Acadesine

Schering-Plough Corporation today announced the start of patient enrollment in RED-CABG, the Phase 3 Trial for acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA). Acadesine was licensed from PeriCor Therapeutics, Inc., a privately held specialty biopharmaceutical company.

12 May 2009

Sinobiopharma announces Chinese approval of Perindopril

Sinobiopharma, Inc. has announced that it has received approval from the Chinese State Food and Drug Administration (SFDA) to manufacture and market its formulation of Perindopril, an anti-hypertension drug.

12 May 2009

Sanofi-aventis to acquire Oforta, oral chronic lymphocytic leukemia treatment

Sanofi-aventis U.S. announced today that it has acquired from biotechnology company Antisoma plc the U.S. commercial rights to Oforta (fludarabine phosphate film-coated tablets), an oral B-cell chronic lymphocytic leukemia (CLL) drug. Oforta is currently approved in the United States for use as a second-line therapy to treat adults with B-cell CLL.

12 May 2009

Hospitals' efforts to reduce readmissions not recognized under current payment model

Hospitals' efforts to reduce the portion of patients who are readmitted for follow-up care are proving successful in many cases, but even though the moves often result in savings for insurers, the hospitals do not necessarily benefit financially, the New York Times reports. Because insurer payments are based on treatments provided rather than the health of patients, hospitals can "actually lose money by providing better care," the Times reports.

12 May 2009

Job losses have negative effect on health, study finds

Workers who lost their job through no fault of their own were twice as likely as continuously employed workers to report over the next 18 months that they developed a new illness, such as high blood pressure, diabetes or heart disease, according to a study released last week, the New York Times reports.

12 May 2009

Omega-three fatty acid rich foods lower risk for eye disease

Regularly eating fish, nuts, olive oil and other foods containing omega-three fatty acids and avoiding trans fats appears to be associated with a lower risk for the eye disease age-related macular degeneration, according to two reports in the May issue of Archives of Ophthalmology.

12 May 2009

DASH diet to lower blood pressure also reduces women's risk of heart failure

The DASH diet was initially developed to help patients lower their blood pressure, but a large study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) demonstrates that women who followed the diet also significantly reduced their risk of developing heart failure.

12 May 2009

New evidence of how high glucose damages blood vessels could lead to new diabetes treatments

New evidence of how the elevated glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the destruction, Medical College of Georgia researchers say.

12 May 2009

High-caloric exercise reduces risks in heart patients the most

An exercise program that burns a lot of calories reduced cardiac risk factors better than standard cardiac rehabilitation in overweight coronary patients, researchers report in Circulation: Journal of the American Heart Association.

12 May 2009

Smoking makes it harder for brain blood flow to recover from long-term heavy drinking

Alcohol-use disorders (AUDs) can damage the brain, particularly the frontal and parietal cortices, although this damage is at least partially reversible with sustained abstinence from alcohol. Chronic smoking is extremely common among individuals with AUDs.

12 May 2009

New genetic clues to treatment of hypertension

An international research team has identified a number of unsuspected genetic variants associated with systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension (high blood pressure), suggesting potential avenues of investigation for the prevention or treatment of hypertension.

12 May 2009

Building a bridge from Alzheimer's disease to diabetes and vice versa

Modern societies face the increasing burden of age-related diseases, in particular Alzheimer's disease (AD) and type 2 diabetes (T2D).

12 May 2009

FHL2 protein regulates blood vessel maintenance

In a study led by Akiko Hata, PhD, of Tufts University School of Medicine, researchers have shown that a protein expressed in the heart, FHL2, inhibits the genes necessary for the quiescence of vascular smooth muscle cells (vSMCs), which line blood vessels.

12 May 2009

Discovery of eight previously unknown genes that affect blood pressure

Eight previously unknown genes that affect blood pressure were recently identified in a comprehensive international study comprising 34,433 Europeans. The findings of the study, in which Uppsala University researchers participated, are being presented in the Web edition of Nature Genetics.

11 May 2009