Blood Vessels News and Research

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How heat affects people with heart failure

Reduced blood flow to the skin’s surface may be a key cause of heat-related illnesses in patients with congestive heart failure, UT Southwestern Medical Center researchers have found.

10 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Avian influenza and the U.S

If a virulent strain of avian influenza ever struck the U.S. poultry industry, this country probably would fare better than many other nations due to careful biosecurity procedures in force.

9 Oct 2005

GRK5 protein plays important role in hypertension

Researchers at Jefferson Medical College have implicated a protein called GRK5 as having an important role behind essential hypertension, which affects more than 65 million Americans.

5 Oct 2005

PACs should not be used routinely in patients in intensive care units with severe heart failure

The use of a pulmonary artery catheter (PAC) -- a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients -- does not appear to improve outcomes nor confer added risks to patients.

4 Oct 2005

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Night-time hemodialysis patients may have a greater capacity to repair their hearts and blood vessels compared to those on conventional dialysis three times a week, according to a study in the October issue of the American Journal of Physiology - Renal Physiology, published by the American Physiological Society.

4 Oct 2005

Role of asymmetric dimethylarginine in damaged blood vessels

A substance found naturally in the blood vessel lining is thought to contribute towards diseases associated with the circulation system, such as heart failure, high blood pressure, stroke and kidney disease.

4 Oct 2005

Gleevec's uses might expand even further

Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway. The Giessen lung researchers now issue a first report of this substance as a new target therapy for pulmonary hypertension

4 Oct 2005

Discovery of mechanisms causing portal hypertension

A physician-scientist at UT Southwestern Medical Center and his research team have identified mechanisms causing a potentially deadly type of hypertension that results from liver damage – findings that could lead to its prevention.

3 Oct 2005

Lack of oxygen in body tissues creates a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung

What's more, the team demonstrated through studies in people and animals that inhalation of a 'souped up' form of nitric oxide, which targets red blood cells, reverses the blood abnormality to restore normal lung pressure.

3 Oct 2005

Steroids significantly reduce heart damage in children with Kawasaki's disease

When added to standard treatment, steroids significantly reduce the odds of developing heart damage in children with Kawasaki's disease, according to a study in the October issue of Pediatrics. These findings address a gap in knowledge.

3 Oct 2005

Plant-derived compounds appear to block the activity of an enzyme that triggers inflammation in joints

The findings came to light while the researchers were studying the wildly different ways in which cells in human blood vessels and joints respond to pressure gradients generated from liquid moving along their surface, a force called shear stress.

3 Oct 2005

Time-to-treatment is important to success of angioplasty treatment

An in-depth look at hospitals that reduced treatment delays highlights steps other hospitals could take to provide rapid angioplasty treatment to heart attack patients, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005

Flavanols help smokers repair blood vessel function

Phytochemicals known as flavanols, which are found in chocolate, fruits and vegetables, can boost the levels of nitric oxide in the blood of smokers and reverse some of their smoking-related impairment in blood vessel function, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005

The immune mechanisms of atherosclerosis

Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones.

28 Sep 2005

Possible therapy that could control blood pressure

A newly developed virus that introduces a blood pressure-lowering gene into cells and enables that gene to maintain blood pressure at healthy levels for four months promises to take gene therapy for the disorder a step closer to reality, said researchers at Baylor College of Medicine in a report released online in the Proceedings of the National Academy of Sciences.

27 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

A fender-bender may have saved Douglas Collins' life. A CT scan following the accident discovered Collins, 64, had a brain aneurysm, a weakness in the arterial wall that if ruptured could cause a stroke or death. It was not caused by the accident, but likely could have been a ticking time bomb present for years. The aneurysm was large and previously thought to require open surgery and a lengthy recovery.

26 Sep 2005

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Israeli scientists report in Human Reproduction that they have successfully transplanted whole frozen and thawed ovaries in sheep, retrieved oocytes from these ovaries and triggered them in the laboratory into early embryonic development.

26 Sep 2005

Blood Vessels News and Research

How heat affects people with heart failure

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Avian influenza and the U.S

GRK5 protein plays important role in hypertension

PACs should not be used routinely in patients in intensive care units with severe heart failure

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Role of asymmetric dimethylarginine in damaged blood vessels

Gleevec's uses might expand even further

Discovery of mechanisms causing portal hypertension

Lack of oxygen in body tissues creates a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung

Steroids significantly reduce heart damage in children with Kawasaki's disease

Plant-derived compounds appear to block the activity of an enzyme that triggers inflammation in joints

Time-to-treatment is important to success of angioplasty treatment

Flavanols help smokers repair blood vessel function

The immune mechanisms of atherosclerosis

Possible therapy that could control blood pressure

"Designer" rats help show how declining estrogen after menopause can affect hypertension

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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