Bone News and Research

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Study provides personalized strategies to boost AIAA compliance in breast cancer patients

Aromatase inhibitor-associated arthralgia (AIAA) is a major side effect in breast cancer survivors, producing joint pain so severe that as many as ten percent of women discontinue their therapy prematurely while undergoing treatment with these lifesaving drugs.

3 Jun 2010

Amedica secures US patent for novel hip implant

Amedica Corporation, a spinal and orthopaedic implant and instrument manufacturer focused on unique silicon nitride (SiN) ceramic technologies, announced today that it has been granted United States Patent No. 7,695,521 covering its novel hip implant featuring a monoblock ceramic acetabular cup for use in articulating joints for total joint replacement.

3 Jun 2010

Researchers develop new technique to detect cathepsin K in atherosclerosis, cancer metastasis

An enzyme implicated in osteoporosis, arthritis, atherosclerosis and cancer metastasis -- cathepsin K -- eluded reliable detection in laboratory experiments in the past. Now, a research team at the Georgia Institute of Technology has developed an assay that reliably detects and quantifies mature cathepsin K using a technique called gelatin zymography.

2 Jun 2010

Genes influence AIAA side effect in breast cancer survivors

2 Jun 2010

Alexion Pharmaceuticals plans to launch Soliris in Japan for patients with PNH

Alexion Pharmaceuticals, Inc. and Alexion Pharma International Sàrl today announced that the launch of Soliris (eculizumab) as a treatment for patients with PNH in Japan will begin in the third quarter of 2010, approximately three months earlier than previously expected.

2 Jun 2010

Excess levels of a protein associated with TNF may produce cognitive decline: Studies

Two new studies suggest that excess levels of a protein associated with inflammation, TNF, may produce cognitive decline. TNF regulates both inflammation and brain function. TNF is elevated in the blood in many autoimmune diseases, and in the fluid surrounding the brain in Alzheimer's disease.

2 Jun 2010

RepRegen reports 3-month data from study of StronBone bioactive glass with Strontium

RepRegen™, the 'smart biomaterials' company previously known as BioCeramic Therapeutics, announced today that three-month data from an in vivo study of its StronBone™ bioactive glass with Strontium demonstrated that it can generate bone quality in and around defects that appears by analytical tests to be significantly superior to a standard bone void filler in the control defect.

2 Jun 2010

UT Southwestern researchers compare TVT and TOT sling procedures for stress urinary incontinence

As part of a national clinical trial, UT Southwestern Medical Center researchers found little difference in effectiveness between two popular treatments for one of the most common ailments among American women: stress urinary incontinence.

2 Jun 2010

$Smoking cessation for first 6-weeks after acute fracture surgery reduces risk of postoperative complications$

Smoking cessation for first 6-weeks after acute fracture surgery reduces risk of postoperative complications

Smokers who refrain from using tobacco during the six-week period following emergency surgery for an acute fracture heal more quickly and experience fewer complications than patients who continue to smoke during the healing process, according to a study published in the June 2010 issue of The Journal of Bone and Joint Surgery (JBJS).

2 Jun 2010

Allos Therapeutics' FOLOTYN data to be presented at 46th ASCO and 15th EHA Congress

Allos Therapeutics, Inc. today announced that data on FOLOTYN® (pralatrexate injection) will be presented at two upcoming medical conferences: the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO), which will be held June 4-8 in Chicago, Illinois, and at the 15th Congress of the European Hematology Association (EHA), which will be held June 10-13 in Barcelona, Spain.

2 Jun 2010

Medicare patients may face accessibility crisis to medical care

According to an article in the June issue of the Journal of Bone and Joint Surgery (JBJS), Medicare patients - many who suffer from disabling arthritis of the hip and knee, among other age-related ailments - may end up facing an accessibility crisis to medical care.

2 Jun 2010

EMBL scientists identify two small RNA molecules that ensure red blood cell production

Red blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second - even more in response to challenges like severe blood loss. In a study published today in the Journal of Experimental Medicine, scientists at the European Molecular Biology Laboratory in Monterotondo, Italy, and EMBL's European Bioinformatics Institute in Hinxton, UK, have identified two small RNA molecules which ensure that enough red blood cells are produced efficiently, by fine-tuning a number of different genes involved in this process.

2 Jun 2010

Amgen's Prolia receives FDA approval for treatment of postmenopausal women with osteoporosis

Amgen Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Prolia™ (denosumab) for the treatment of postmenopausal women with osteoporosis at high risk for fracture, defined as a history of osteoporotic fracture, or multiple risk factors for fracture; or patients who have failed or are intolerant to other available osteoporosis therapy. Prolia, the first and only FDA-approved RANK Ligand inhibitor, is an every six month 60 mg subcutaneous injection administered by a health care professional.

2 Jun 2010

New model reveals molecular basis of multiple hereditary exostoses

Children born with multiple hereditary exostoses (MHE) suffer from abnormal growths on their bones. These bony protrusions stunt their growth and can cause pain and disfigurement.

2 Jun 2010

FDA approves Prolia for postmenopausal women with osteoporosis

The U.S. Food and Drug Administration approved Prolia, an injectable treatment for postmenopausal women with osteoporosis who are at high risk for fractures.

2 Jun 2010

Sticky gel composed of MPEG-pDHA may help seal wounds created by surgery: Study

A compound found in sunless tanning spray may help to heal wounds following surgery, according to new results published by plastic surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City and biomedical engineers at Cornell University in Ithaca, N.Y., where the novel compound was developed.

1 Jun 2010

U.S. Department of Defense OTT initiative to replace scars and defects with healthy, functional tissues

A two-year, $12 million contract with the U.S. Department of Defense Office of Technology Transition (OTT) will jumpstart human trials of three innovative research programs that aim to replace scars and defects with healthy, functional tissues, announced officials of the University of Pittsburgh and the McGowan Institute for Regenerative Medicine today at the Institute's Second Annual Open Session, Soldiers and Sailors Memorial Hall, Oakland.

31 May 2010

AAID's advice on teeth suddenly knocked out

Chicago Blackhawks star Duncan Keith's dental misfortune on the ice is an occupational hazard for hockey players, but teeth also can be lost in accidents, sports mishaps and falls that can happen to anyone. So what should you do when one or more of your teeth are suddenly knocked out?

29 May 2010

Focused Ultrasound Surgery Foundation welcomes abstracts on MR-guided focused ultrasound

The Focused Ultrasound Surgery Foundation has announced that abstract submissions and registration are now open for the 2nd International Symposium on MR-guided Focused Ultrasound and can be accessed online at www.fusfoundation.org/symposium.

29 May 2010

Hebrew Union College honors Dr. Dean Lorich with 2010 Roger E. Joseph Prize for humanitarian efforts

Dr. Dean Lorich was honored with the 2010 Roger E. Joseph Prize by Hebrew Union College for his humanitarian efforts in treating victims of the recent Haiti earthquake and in Landstuhl, Germany treating soldiers injured in Iraq and in Afghanistan. The award recognizes individuals making lasting contributions to the causes of human rights.

29 May 2010

Bone News and Research

Study provides personalized strategies to boost AIAA compliance in breast cancer patients

Amedica secures US patent for novel hip implant

Researchers develop new technique to detect cathepsin K in atherosclerosis, cancer metastasis

Genes influence AIAA side effect in breast cancer survivors

Alexion Pharmaceuticals plans to launch Soliris in Japan for patients with PNH

Excess levels of a protein associated with TNF may produce cognitive decline: Studies

RepRegen reports 3-month data from study of StronBone bioactive glass with Strontium

UT Southwestern researchers compare TVT and TOT sling procedures for stress urinary incontinence

Smoking cessation for first 6-weeks after acute fracture surgery reduces risk of postoperative complications

Allos Therapeutics' FOLOTYN data to be presented at 46th ASCO and 15th EHA Congress

Medicare patients may face accessibility crisis to medical care

EMBL scientists identify two small RNA molecules that ensure red blood cell production

Amgen's Prolia receives FDA approval for treatment of postmenopausal women with osteoporosis

New model reveals molecular basis of multiple hereditary exostoses

FDA approves Prolia for postmenopausal women with osteoporosis

Sticky gel composed of MPEG-pDHA may help seal wounds created by surgery: Study

U.S. Department of Defense OTT initiative to replace scars and defects with healthy, functional tissues

AAID's advice on teeth suddenly knocked out

Focused Ultrasound Surgery Foundation welcomes abstracts on MR-guided focused ultrasound

Hebrew Union College honors Dr. Dean Lorich with 2010 Roger E. Joseph Prize for humanitarian efforts

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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