Bone News and Research

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Study shows beneficial effect of walking on the reduction in risk of bone marrow lesions in the knee

The world's most common joint disease, osteoarthritis (OA) is a major cause of disability among adults over the age of 50.

29 Sep 2007

Study of bone marrow stem cells in multiple sclerosis

A new pilot clinical trial to test bone marrow stem cell therapy with a small group of patients with multiple sclerosis has started at Frenchay Hospital.

27 Sep 2007

Survival data presented from phase II study of hormone-resistant prostate cancer patients

The results from the randomized, double -blind, placebo -controlled, Phase II EPOC (Endothelin A Proof Of Concept) Study of ZD4054 - a specific endothelin A (ETA) receptor antagonist – were delivered at the 14th European Congress of Clinical Oncology (ECCO, 23-27 September, Barcelona).

26 Sep 2007

New AstraZeneca compound shows promoise for hormone resistant prostate cancer patients with bone metastases

New Phase II data suggests that ZD4054, a novel compound in development for the treatment of men with Hormone Resistant Prostate Cancer (HRPC), could offer a promising improvement in overall survival in men with metastatic HRPC who were asymptomatic or mildly symptomatic for pain.

26 Sep 2007

Manipulating immune response provides new approach to liver failure

If the results of the animal study can be applied in human patients, the approach may be able to keep patients alive until donor organs become available or to support liver function until the organ can regenerate itself, eliminating the need for a transplant.

25 Sep 2007

Relief for arthritic knees

If you're among the estimated 10 million Americans who have been diagnosed with osteoarthritis of the knee, take heart in knowing that several nonsurgical options, pharmacologic and otherwise, are available for easing the pain of an arthritic knee, according to Cleveland Clinic's Arthritis Advisor.

25 Sep 2007

Novel strategy to tackle acute myelogenous leukemia

A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say.

25 Sep 2007

$New treatment for fractures$

New treatment for fractures

Russian researchers have investigated methods of healing bones without extensive operations, long-term bone fixation or expensive stimulating drugs, using tests on animal subjects.

25 Sep 2007

Cancer cells in blood can identify risk of recurrence in breast cancer

Cancer cells circulating in the blood, or circulating tumour cells (CTCs), are known to be associated with a bad prognosis in women with metastatic breast cancer.

25 Sep 2007

Cancer cells in blood can identify risk of recurrence in breast cancer

Cancer cells circulating in the blood, or circulating tumour cells (CTCs), are known to be associated with a bad prognosis in women with metastatic breast cancer. Now, for the first time, a group of scientists have shown that they can also detect CTCs before and after chemotherapy treatment and hence may be able to identify those patients likely to have a recurrence of their cancer after such treatment in future.

24 Sep 2007

New UK stem cell and regenerative medicine research centre

The new Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM) will be officially opened at the University of Nottingham on the 21st September, 2007 by Sir Keith O’Nions, Director General Science and Innovation at the Department for Innovation, Universities and Skills.

24 Sep 2007

Framingham Heart Study 100K result published

BioMed Central has announced that 17 research articles carried out using genetic data from the Framingham Heart Study (FHS), are being published as a supplement to BMC Medical Genetics.

23 Sep 2007

$Women with low levels of vitamin D have an increased risk of hip fracture$

Women with low levels of vitamin D have an increased risk of hip fracture

Women with low levels of vitamin D have an increased risk of hip fracture, according to a study led by the University of Pittsburgh Graduate School of Public Health presented this week at the 29th annual meeting of the American Society for Bone and Mineral Research at the Hawaii Convention Center.

21 Sep 2007

Genes for osteoporosis

Researchers at Hebrew SeniorLife's Institute for Aging Research (IFAR) have examined close to 100,000 genetic markers for low bone mass and aging to help determine which genes are responsible for the development of osteoporosis and longevity.

21 Sep 2007

Discovery of cause of Job's syndrome

The rare immunodeficiency disorder known as Job's syndrome is caused by a specific genetic mutation that both overstimulates and understimulates the human immune system, leading to harmful bacterial and fungal infections and the physical features characteristic of the syndrome, according to two independent groups of scientists, one from the National Institutes of Health (NIH) and the other from the Tokyo Medical and Dental University.

20 Sep 2007

Cell growth technology promises more successful drug development

Scientists have developed unique technology to grow stem cells and other tissue in the laboratory in conditions similar to the way they grow in the human body.

20 Sep 2007

3-D Petri dish that grows cells in three dimensions

A team of Brown University biomedical engineers has invented a 3-D Petri dish that can grow cells in three dimensions, a method that promises to quickly and cheaply produce more realistic cells for drug development and tissue transplantation.

20 Sep 2007

Risedronate prevents bone loss after breast cancer treatment

Breast cancer survivors who took a weekly dose of risedronate, sold as Actonel, lost significantly less bone than those who did not take the drug, according to a two-year study from the University of Pittsburgh School of Medicine presented this week at the 29th annual meeting of the American Society for Bone and Mineral Research.

18 Sep 2007

Re-engineered human T cells effectively target and kill cancerous B cells

Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

18 Sep 2007

Sexual function affected by stem cell transplant according to long-term study

A long-term study found that a type of stem cell transplant used for patients with life-threatening diseases, such as leukemia and lymphoma, results in decreased sexual function and activity for recipients.

18 Sep 2007