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Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Study recommends treatment change for pre-leukemia disease

A new study finds that longer courses of a mild form of chemotherapy may help patients with a bone marrow disease only recently considered a form of cancer.

14 Mar 2006

Decitabine improves myelodysplastic syndrome treatment

A potent member of a new class of drugs increases survival in some patients with myelodysplastic syndrome (MDS), and may become the new standard of therapy for this group of pre-cancer disorders

14 Mar 2006

Decitabine improves patient outcomes in myelodysplastic syndromes

Decitabine, a new drug undergoing Phase III efficacy trials, provides palliative therapy for patients with the bone marrow disease called Myelodysplastic Syndrome (MDS), according to a new study.

14 Mar 2006

Emergency departments score poorly in child-saving drills

A mock-drill study conducted in a third of North Carolina's hospital emergency departments (EDs) revealed that nearly all failed to properly stabilize seriously injured children during trauma simulations, according to a team of researchers at the Johns Hopkins Children's Center and Duke University Medical Center.

13 Mar 2006

High levels of a salivary protein IL-1-beta associated with increased bone loss

Researchers at the University at Buffalo have identified two components of saliva that may serve as the basis for novel tests to determine the risk for future loss of the bone that holds teeth in place.

13 Mar 2006

RvE1 protects from inflammation and bone loss in experimental periodontitis

Gum disease is initiated by bacteria populating dental plaque and may eventually result in tissue and tooth loss.

13 Mar 2006

Components found in red wine can help prevent periodontal diseases

Periodontitis is a progressive infectious disease affecting the gums and bone that surround and support teeth, often causing tooth movement and leading to permanent tooth loss.

13 Mar 2006

A more accurate method for measuring blood levels of endothelial progenitor cells

A more accurate method for measuring blood levels of specialized cells that circulate in the bloodstream and repair damage to the arterial lining has been discovered by Duke University Medical Center cardiologists.

13 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

Pregnancy diet has lifelong effects for baby

University of Nottingham researchers are targeting Europe's biggest killer diseases - by focusing on the diet of unborn babies.

8 Mar 2006

Scientists fight leukaemia with 'natural killer' cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children's Hospital have just won funding for a two-year project aimed at improving the outcome of bone marrow stem-cell transplants in young leukaemia patients.

8 Mar 2006

Cells used in bone marrow transplantation can develop into new cells lining the gut

The study showed that bone marrow derived cells can differentiate into functional gastrointestinal epithelial cells after bone marrow transplantation.

7 Mar 2006

Interferon-producing killer dendritic cell speeds up immune reactions and fights cancer

A mouse immune cell that plays dual roles as both assassin and messenger, normally the job of two separate cells, has been discovered by an international team of researchers from the United States and France.

7 Mar 2006

Orthopaedic medical device technologies that offer greater clinical benefits expected to succeed

Current users of medical device technologies for orthopaedic applications seek systems that offer maximum comfort while requiring minimum physical supervision. This is driving the market to continuously evolve technologies that use radically different approaches or make significant improvements to existing products.

6 Mar 2006

Mosquito virus kills 78 in a month - Indian ocean fears epidemic

While the rest of the world panics about bird flu, the islands of Mauritius, Reunion and the Seychelles in the Indian Ocean are in the grip of a mosquito-borne epidemic that has infected thousands and killed at least 78 in a month.

6 Mar 2006

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.

1 Mar 2006

Bone marrow stem cells do not improve cardiac function in heart attack patients

There has been increasing evidence that stem cells contribute to regeneration of cardiac tissue and the development of new blood vessels following a heart attack, thus opening up new prospects for stem-cell based therapies.

1 Mar 2006