Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Regulatory T cells learn what to protect while in the thymus and that everything the cells learn may not be good

Regulatory T cells, which function like immune system police, learn early in life what to protect, and that may include viruses, bacteria and tumors, researchers have shown.

3 Aug 2006

Bone marrow lesions in the knee may be hereditary

There is a significant genetic component to the occurrence and severity of bone marrow lesions in the tibia and femur.

3 Aug 2006

Researchers determine why gene therapy treatment caused leukemia in some X-linked severe combined immunodeficiency patients

Scientists at St. Jude Children's Research Hospital have developed a mouse model of a severe disease of the immune system that helps explain why gene therapy used to treat children with this disease at an institution in Europe caused some of them to develop leukemia.

2 Aug 2006

Knee bone marrow lesions may be hereditary

Bone marrow lesions in the knee, a cause of pain in patients with knee osteoarthritis, may be hereditary.

1 Aug 2006

Leukemia gene normally has mammary gland function

A gene critical for normal mammary gland function during nursing helps trigger highly lethal leukemias when it undergoes a mutation that fuses it to another gene, according to investigators at St. Jude Children's Research Hospital.

19 Jul 2006

Researchers isolate rare cancer stem cells that cause leukemia

Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston and their colleagues have isolated rare cancer stem cells that cause leukemia in a mouse model of the human disease.

18 Jul 2006

New genetic clues to dementia with Lewy bodies

Researchers have found that genetic alterations originally identified in people suffering from a rare disease may also be an important risk factor for the second most common form of dementia among the elderly.

17 Jul 2006

Research may pave the way for alternative treatments using cell replacements instead of organ transplants for those with liver failure

University of Edinburgh scientists have identified primitive liver cells -possibly dormant from the earliest developmental stage of a human being - which have the potential to mature into different cells types and help repair a failing liver.

9 Jul 2006

Study shows eggs survive in older ovaries

In research that could have broad implications for women's fertility treatments, scientists have found that despite their age, female mice have a renewable egg supply in their ovaries.

5 Jul 2006

Female mice found to have a renewable egg supply

In research that could have broad implications for women's fertility treatments, scientists have found that despite their age, female mice have a renewable egg supply in their ovaries.

4 Jul 2006

Researchers develop T-cells from human embryonic stem cells

Human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS.

3 Jul 2006

Potential permanent genetic cure for hemophilia A

A discovery by Medical College of Wisconsin and BloodCenter of Wisconsin researchers in Milwaukee may be a key to a permanent genetic cure for hemophilia A patients, including a subset who do not respond to conventional blood transfusions.

3 Jul 2006

Bone marrow adult stem cells repair a damaged heart

Researchers at the McEwen Centre for Regenerative Medicine at Toronto General Hospital have discovered the 'SOS' distress signal that mobilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack.

3 Jul 2006

FDA grants accelerated approval for Sprycel (dasatinib)

FDA grants accelerated approval for Sprycel (dasatinib), a new oral treatment for patients with chronic myeloid leukemia (CML),

29 Jun 2006

Electricity used to engineer human tissue

Scientists at The University of Manchester have developed a new technique which uses electricity to engineer human tissue.

From The University of Manchester 26 Jun 2006

Injection may prevent infertility in men receiving cancer chemotherapy

It may be possible to protect the testes of cancer patients against the loss of fertility caused by chemotherapy.

20 Jun 2006

New roles for growth factors

During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target.

18 Jun 2006

Circulating bone-marrow derived cells do not contribute to egg formation

Ovulated egg cells, or oocytes, in adult female mice are not formed from germ cells in the blood or bone marrow.

14 Jun 2006

University of Florida finding could lead to approaches to treat macular degeneration

University of Florida scientists conducting experiments with mice have found evidence that the body naturally replenishes small amounts of cells in the eye essential for healthy vision.

9 Jun 2006

Glivec the best news yet for cancer victims

In what is great news for those suffering from chronic myeloid leukaemia (CML), the drug Glivec looks like being one of the biggest breakthroughs in cancer therapy for a years.

7 Jun 2006