Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

Molecular and serum markers of prognosis in renal cell carcinoma have remained elusive. In large part, tumor (TNM) stage, Fuhrman grade, and patient performance status have stood the test of time as the most valuable factors in predicting patient outcome following surgery.

15 Mar 2006

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Scientists gain better understanding of the behavior of leukemic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Study recommends treatment change for pre-leukemia disease

A new study finds that longer courses of a mild form of chemotherapy may help patients with a bone marrow disease only recently considered a form of cancer.

14 Mar 2006

Decitabine improves myelodysplastic syndrome treatment

A potent member of a new class of drugs increases survival in some patients with myelodysplastic syndrome (MDS), and may become the new standard of therapy for this group of pre-cancer disorders

14 Mar 2006

Decitabine improves patient outcomes in myelodysplastic syndromes

Decitabine, a new drug undergoing Phase III efficacy trials, provides palliative therapy for patients with the bone marrow disease called Myelodysplastic Syndrome (MDS), according to a new study.

14 Mar 2006

A more accurate method for measuring blood levels of endothelial progenitor cells

A more accurate method for measuring blood levels of specialized cells that circulate in the bloodstream and repair damage to the arterial lining has been discovered by Duke University Medical Center cardiologists.

13 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006

Scientists fight leukaemia with 'natural killer' cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children's Hospital have just won funding for a two-year project aimed at improving the outcome of bone marrow stem-cell transplants in young leukaemia patients.

8 Mar 2006

Cells used in bone marrow transplantation can develop into new cells lining the gut

The study showed that bone marrow derived cells can differentiate into functional gastrointestinal epithelial cells after bone marrow transplantation.

7 Mar 2006

Interferon-producing killer dendritic cell speeds up immune reactions and fights cancer

A mouse immune cell that plays dual roles as both assassin and messenger, normally the job of two separate cells, has been discovered by an international team of researchers from the United States and France.

7 Mar 2006

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.

1 Mar 2006

Bone marrow stem cells do not improve cardiac function in heart attack patients

There has been increasing evidence that stem cells contribute to regeneration of cardiac tissue and the development of new blood vessels following a heart attack, thus opening up new prospects for stem-cell based therapies.

1 Mar 2006

New findings on epoetin alfa for anemia

Mayo Clinic researchers working in concert with other North Central Cancer Treatment Group (NCCTG) investigators have found that administering epoetin alfa for anemia once every three weeks to patients with anemia and cancer, instead of the traditional weekly epoetin treatments, maintains similar levels of red blood cells.

1 Mar 2006

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes.

23 Feb 2006

Reovirus may be able to eliminate cancer cells from autologous stem cell transplants

Medical studies show that a common virus may be able to eliminate cancer cells from autologous stem cell transplants.

21 Feb 2006

New device to boost supply and quality of blood platelets

Cancer and open-heart surgery patients, disaster victims, organ or bone marrow transplant recipients, and others who require life-saving blood platelet transfusions will benefit from equipment invented by a researcher at the University of British Columbia's Centre for Blood Research (CBR).

21 Feb 2006

Protein levels predict bone marrow transplant survival

Researchers say that protein levels can predict which bone marrow transplant patients are likely develop a deadly complication a week after the procedure and well before any symptoms occur.

19 Feb 2006

Bone Marrow News and Research

Further Reading

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists gain better understanding of the behavior of leukemic cells

Researchers find viable new sources for stem cell transplants to the heart

Creative new therapies for atherosclerotic disease

Study recommends treatment change for pre-leukemia disease

Decitabine improves myelodysplastic syndrome treatment

Decitabine improves patient outcomes in myelodysplastic syndromes

A more accurate method for measuring blood levels of endothelial progenitor cells

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Scientists fight leukaemia with 'natural killer' cells

Cells used in bone marrow transplantation can develop into new cells lining the gut

Interferon-producing killer dendritic cell speeds up immune reactions and fights cancer

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Bone marrow stem cells do not improve cardiac function in heart attack patients

New findings on epoetin alfa for anemia

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

Reovirus may be able to eliminate cancer cells from autologous stem cell transplants

New device to boost supply and quality of blood platelets

Protein levels predict bone marrow transplant survival

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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