Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

New compound that is designed to overcome Gleevec resistance

One of the truly spectacular success stories in modern oncology is the development and implementation of Gleevec, a drug that virtually halts the progress of chronic myeloid leukemia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably.

17 Jul 2004

Using a combination of therapies and cell grafts could help treat patients with chronic spinal cord injuries

Using a combination of therapies and cell grafts, a team of University of California, San Diego (UCSD) School of Medicine researchers has promoted significant regeneration of nerve cells in rats with spinal cord injury.

15 Jul 2004

Animal bone implants that resemble natural bone

A team of researchers at the Institute of Bioengineering and Nanotechnology (IBN) has moved one step closer to developing an ideal bone scaffold for reconstructive surgery.

15 Jul 2004

Immunotherapeutic strategy allowing patients to use their own immune system to fight their cancer

Scientists affiliated with the Harvard University Medical School have devised ways of bolstering patients' immune response against kidney and breast cancer.

15 Jul 2004

The structure of AGT shows how one human protein reduces the potency of chemotherapy

The fine details of this x-ray structure may help scientists find ways to fight certain cancers, such as brain tumors, which express high levels of AGT making them resistant to chemotherapy.

9 Jul 2004

Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells

Results of a randomised trial in this week’s issue of THE LANCET suggest that the transfer of adult stem cells derived from bone marrow could improve cardiac functioning after heart attack.

8 Jul 2004

A new protocol for bone marrow transplants

A new protocol for bone marrow transplants, which does not require the destruction of the recipient’s immune system before transfer of the new bone marrow, is described by a group of Oxford scientists

5 Jul 2004

Guidelines for determining the best possible time to receive bone marrow transplants

Bone marrow transplant, the only cure for patients with myelodysplastic syndrome (MDS), is a life-saving procedure but carries with it many risks and potential side effects.

2 Jul 2004

Launch of the Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies

Mattel Children's Hospital at UCLA announced the launch of the Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies at UCLA June 28.

29 Jun 2004

Results from study of Rituxan in rheumatoid arthritis show promise

Genentech, Inc., Biogen Idec and Roche have announced that the New England Journal of Medicine published the results of a Phase IIa study showing that two doses of Rituxan® (Rituximab), administered two weeks apart, improved symptoms in patients with moderate-to-severe rheumatoid arthritis (RA) for up to 48 weeks when combined with methotrexate (MTX), compared to MTX alone.

16 Jun 2004

U.S.$2.8 to study a virus associated with respiratory infections

The Center for Emerging Infectious Diseases (CEID), based in the University of Iowa College of Public Health, has been awarded a five-year, $2.8 million grant by the National Institute of Allergy and Infectious Diseases to study a virus associated with respiratory infections.

11 Jun 2004

The mother of four boys with one of the world's rarest illnesses has donated her bone marrow to her eldest son

A mum whose four sons all suffer from a rare life threatening disease yesterday donated her bone marrow to her eldest son Josh. Allison Hartley was found to be a match for 12-year-old Joshua, who has the rare degenerative condition XLP.

11 Jun 2004

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

Though there has been considerable biological and political debate over the use of embryonic stem cells (ESCs) vs. adult stem cells (ASCs) as therapies for tissue engineering and organ transplants, inherent benefits and drawbacks in both techniques compel them to coexist and complement each other.

10 Jun 2004

New drugs ease treatment of multiple myeloma

Science is increasingly commuting the death sentence that is a diagnosis of multiple myeloma. A cancer of the plasma cells that primarily strikes the elderly, multiple myeloma has been deadly because patients have been unable to withstand the aggressive treatment necessary to combat it.

10 Jun 2004

New statistical techniques for cancer diagnosis

CSIRO statisticians have developed a new way to subtype paediatric Acute Lymphoblastic Leukaemia (ALL), the most common form of cancer in children under 12.

9 Jun 2004

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

A biological agent — a drug that wraps vitamin A inside bubbles of fat — used without chemotherapy appears to offer as many as one-third of patients with a rare form of leukemia an opportunity for a long-term, disease-free future, say researchers at The University of Texas M. D. Anderson Cancer Center.

7 Jun 2004

Velcade major improvement over standard therapy for relapsed multiple myeloma

Early results from a major, international Phase III clinical trial decisively show that recurrent multiple myeloma is more effectively treated with the drug bortezomib (trade name: Velcade TM) than with dexamethasone, a drug that for decades has been the standard therapy for relapsed disease, researchers at Dana-Farber Cancer Institute report.

6 Jun 2004

Umbilical cord blood and bone marrow transplants slow the progression of many cancers

Umbilical cord blood and bone marrow transplants at Loyola University Health System, Maywood, Ill., are curing or slowing the progression of many cancers originating in the bone marrow (i.e., leukemia, myeloma) or lymphatic system (lymphoma).

3 Jun 2004

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Bone marrow stem cells, when exposed to damaged liver tissue, can quickly convert into healthy liver cells and help repair the damaged organ, according to new research from the Johns Hopkins Kimmel Cancer Center.

2 Jun 2004

Marijuana use does not appear to be associated with an increased risk of developing oral cancer

Contrary to previous research findings that have suggested a link, marijuana use does not appear to be associated with an increased risk of developing oral cancer, according to a large, population-based study led by researchers at Fred Hutchinson Cancer Research Center.

1 Jun 2004

Bone Marrow News and Research

Further Reading

New compound that is designed to overcome Gleevec resistance

Using a combination of therapies and cell grafts could help treat patients with chronic spinal cord injuries

Animal bone implants that resemble natural bone

Immunotherapeutic strategy allowing patients to use their own immune system to fight their cancer

The structure of AGT shows how one human protein reduces the potency of chemotherapy

Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells

A new protocol for bone marrow transplants

Guidelines for determining the best possible time to receive bone marrow transplants

Launch of the Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies

Results from study of Rituxan in rheumatoid arthritis show promise

U.S.$2.8 to study a virus associated with respiratory infections

The mother of four boys with one of the world's rarest illnesses has donated her bone marrow to her eldest son

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

New drugs ease treatment of multiple myeloma

New statistical techniques for cancer diagnosis

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

Velcade major improvement over standard therapy for relapsed multiple myeloma

Umbilical cord blood and bone marrow transplants slow the progression of many cancers

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Marijuana use does not appear to be associated with an increased risk of developing oral cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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