Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Yo-yo dieting may have a lasting negative impact on immune function

Yo-yo dieting, in which a person repeatedly loses and regains weight, may have a lasting negative impact on immune function, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

1 Jun 2004

Cigarette smoking linked to leukemia

Cigarette smoking has been linked to acute myelogenous leukemia, according to The Health Consequences of Smoking: A Report of the Surgeon General, released today.

27 May 2004

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Researchers in the department of ophthalmology at the University of Arizona College of Medicine in Tucson played an important role in the development of Restasis, the first alternative to artificial tears for the treatment of dry eye syndrome.

21 May 2004

FDA finalizes new rule on donor eligibility for human tissues and cells

FDA today published a final rule establishing donor eligibility criteria for donors of human cells, tissues, and cellular and tissue-based products (HCT/Ps) to help prevent the transmission of communicable disease when these products are transplanted.

20 May 2004

Patients with leukemia or lymphoma who undergo hematopoietic-cell transplantation and survive can expect full recovery to take 3-5 years

Patients with leukemia or lymphoma who undergo hematopoietic-cell transplantation (HCT) and survive can expect full recovery to take 3-5 years, according to a study published in the May 19 issue of The Journal of the American Medical Association (JAMA).

19 May 2004

$First drug approved for hormone refractory prostate cancer that has shown a survival benefit$

First drug approved for hormone refractory prostate cancer that has shown a survival benefit

The the Food and Drug Administration (FDA) approved Taxotere (docetaxel), injection in combination with prednisone ( a steroid), for the treatment of patients with advanced metastatic prostate cancer. This is the first drug approved for hormone refractory prostate cancer that has shown a survival benefit.

19 May 2004

FDA approves new drug for bone marrow disease

The Food and Drug Administration (FDA) today announced the approval of Vidaza (azacitidine) injection, the first effective treatment for patients with Myelodysplastic Syndrome (MDS). The product was given Fast Track Status and a priority review.

19 May 2004

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Inactivating a protective molecule in leukemic cells to make them more vulnerable to chemotherapy might also make healthy blood-forming cells more sensitive to the toxic effects of those same drugs.

19 May 2004

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

Using genetically engineered mice, researchers at the Johns Hopkins Children's Center have identified a gene that functions as a cancer-causing gene (or oncogene) and may play a key role in the development of leukemia and other cancers in children and adults.

15 May 2004

New Center for International Blood and Marrow Transplant Research

In their mission to improve transplant access and outcomes for patients, the National Marrow Donor Program® (NMDP) and the Medical College of Wisconsin’s International Bone Marrow Transplant Registry and Autologous Blood and Marrow Transplant Registry (IBMTR/ABMTR) have created the Center for International Blood and Marrow Transplant Research (CIBMTR.)

14 May 2004

Study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus

The study will include a basic research component to examine the roles of B and T cells, white blood cells in the immune system, in triggering lupus symptoms.

14 May 2004

Embryonic stem cells may hold the key to regenerating damaged heart muscle

Embryonic stem cells may hold the key to regenerating damaged heart muscle, when transplanted within a 3-dimensional scaffold into the infracted heart, according to a new study coming out in June in the Journal of Heart and Lung Transplantation.

14 May 2004

New research center created by leading blood and marrow transplant organizations

11 May 2004

Bone marrow and stem cell transplantation rejection averted by UV light exposure

One of the unfortunate side effects of bone marrow and stem cell transplantation is that the newly implanted cells often stage an internal attack against the patient they're intended to help.

10 May 2004

World's first gene therapy trial aimed at preventing cancer

The concept seems straightforward. If, at its heart, cancer is a disease of genes, then giving patients new genes should disarm cancer. Such treatment would replace missing or faulty genes that keep cell growth in check, or would flush the body with "super genes" that could attack and destroy cancer.

5 May 2004

Embryo testing could produce babies who might aid sick siblings

Parents with a child requiring stem cell transplantation can have genetic testing done on embryos prior to implantation to determine if the tissue type matches and the ensuing offspring could potentially serve as a donor to the affected child, according to a study in the May 5 issue of The Journal of the American Medical Association (JAMA).

5 May 2004

New technique to deliver gene therapy to soft-tissue tumors

Using new research and technology that shows bone marrow-derived mesenchymal stem cells (MSCs) will engraft at the site of a tumor and contribute to the growth of stromal fibroblasts (the healthy tissue surrounding a tumor)

2 May 2004

Transplanted bone-marrow cells could regenerate nerve cells in the brain

Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease.

29 Apr 2004

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

Transkaryotic Therapies, Inc. today announced that it has initiated a clinical trial to evaluate the safety and clinical activity of GA-GCB, its enzyme replacement therapy for the treatment of Gaucher disease.

26 Apr 2004

Injections of adult stem cells could repair hearts

Injections of adult stem cells into damaged heart tissue significantly improved heart function in patients with severe congestive heart failure, according to results of the first prospective randomized trial of the experimental therapy presented today at the American Association for Thoracic Surgery.

26 Apr 2004

Bone Marrow News and Research

Further Reading

Yo-yo dieting may have a lasting negative impact on immune function

Cigarette smoking linked to leukemia

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

FDA finalizes new rule on donor eligibility for human tissues and cells

Patients with leukemia or lymphoma who undergo hematopoietic-cell transplantation and survive can expect full recovery to take 3-5 years

First drug approved for hormone refractory prostate cancer that has shown a survival benefit

FDA approves new drug for bone marrow disease

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

New Center for International Blood and Marrow Transplant Research

Study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus

Embryonic stem cells may hold the key to regenerating damaged heart muscle

New research center created by leading blood and marrow transplant organizations

Bone marrow and stem cell transplantation rejection averted by UV light exposure

World's first gene therapy trial aimed at preventing cancer

Embryo testing could produce babies who might aid sick siblings

New technique to deliver gene therapy to soft-tissue tumors

Transplanted bone-marrow cells could regenerate nerve cells in the brain

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

Injections of adult stem cells could repair hearts

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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