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Gene that affects alcohol sensitivity

Since one of the basic risk factors for alcoholism is a tolerance to alcohol, researchers have long sought to understand the genetic differences among people that affect their sensitivity to alcohol. So far, scientists have met with little success.

9 Jun 2004

Genetic signature associated with the aging human brain

Unraveling the mysteries of the aging brain is a major goal for brain science, especially given the exploding population of senior citizens and the obvious desire to preserve brain function as long as possible.

9 Jun 2004

Exercise can help brain healing process

Exercise can stimulate injured neurons to regenerate their axons, which are the primary transmission lines of the nervous system, according to a study published June 1 in the print edition of the Proceedings of the National Academy of Sciences, and the last week of May in the early online edition.

2 Jun 2004

International adult stem cell 'retraining' project starts in Birmingham

An exciting research project to utilise the body's own stem cells to regenerate areas of tissue damage is uniting scientists in Birmingham, London and Ontario, Canada. The University of Birmingham is leading a three year study with long term aims of helping stroke, Parkinsons and diabetes patients.

27 May 2004

Brain cells containing the chemical histamine are critical for waking

A study by scientists with the Veterans Affairs' Neurobiology Research Laboratory and UCLA Neuropsychiatric Institute shows that brain cells containing the chemical histamine are critical for waking.

27 May 2004

Data suggests potential target for Alzheimer's disease treatment

Researchers from Weill Cornell Medical College and Columbia University College of Physicians & Surgeons have discovered at least one way in which beta-amyloid, the protein that forms stubborn plaques in the brains of Alzheimer's disease patients, can kill nerve cells.

25 May 2004

Are we as crazy as mad cows?

When proteins in our body work properly, we can see, smell, consume and digest food, grow muscle and brain cells. But when these infinitely useful biological building blocks fail, the most pernicious diseases arise. Susan Lindquist has scrutinized the complex origami-like shapes of proteins and come to understand how structural mistakes can lead to a frightening class of neurodegenerative disorders, including “Mad Cow Disease.”

20 May 2004

Research into sleeping disorder drug may help multiple sclerosis patients

A University of Nottingham academic is leading a research project looking at whether a drug produced for a sleeping disorder could improve the quality of life for thousands of multiple sclerosis patients.

17 May 2004

The Stroke Association have found that surgery can halve the risk of a stroke

Scientists funded by the Medical Research Council (MRC) and The Stroke Association have found that surgery can halve the risk of a stroke for people who have significant narrowing of the main artery carrying blood to the brain. Their findings, published in this week’s The Lancet, are the result of a large-scale international clinical trial.

14 May 2004

Underage drinking mayhem?

As the school year comes to an end across the United States, many teenagers will attend high school proms, celebrate high school or college graduations, and take trips to local beaches for senior week.

10 May 2004

A computer-based test that detects impaired cognition has been developed

A computer-based test that detects impaired cognition has been developed by researchers from Monash University's Psychology department and could be used to identify people who are affected by drugs, chronic fatigue or even hangovers.

10 May 2004

Brain damage at birth can be reversed

More than 1000 children die or suffer permanent brain injury every year in the UK because of shortage of oxygen around the time of birth. Tragedy can strike without warning, and often following normal healthy pregnancies. If the baby survives major problems include severe cerebral palsy, learning difficulties and epilepsy.

6 May 2004

Gene therapy helps alcoholic rats

As a follow up to previous work showing that gene therapy can reduce drinking in rats trained to prefer alcohol, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have used the same technique to cut drinking in rats with a genetic predisposition for heavy alcohol consumption.

5 May 2004

Tooth cells may help treat Parkinson's disease

Cells derived from the inside of a tooth might someday prove an effective way to treat the brains of people suffering from Parkinson's disease.

4 May 2004

Chemical thumbprint can help determine if tumor is returning or dying

Brain tumor survivors live with the constant worry that their cancer might come back. And even if they have a brain scan every few months to check, doctors often can't tell the difference between new cancer growth and tissue changes related to their treatment with radiation or chemotherapy.

3 May 2004

Males and females respond differently to brain injury

Researchers at Children’s Hospital of Pittsburgh have found that males and females respond differently to brain injury and therefore, boys with brain injuries may require different life-saving treatments than girls.

1 May 2004

Results look promising in Alzheimer’s gene therapy trial

Surgical placement of genetically modified tissue directly into the brains of patients with Alzheimer’s disease, an experimental approach to delaying brain cell loss associated with the disease, leads to increased metabolic activity in the brain, with cells apparently responding to the insertion of growth factor-producing grafts

28 Apr 2004

People with uncontrolled epilepsy have low levels of a certain fatty acid

Omega-3 fatty acids are crucial to the proper development and function of cell membranes in the brain. But one particular fatty acid, docosahexaenoic acid (DHA), is found at abnormally low levels in patients with uncontrolled epilepsy, according to researchers at Emory University in Atlanta, GA.

28 Apr 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004

Nitric oxide, a chemical messenger involved in bodily functions shuts down a protein involved in Parkinson's disease

Johns Hopkins researchers have discovered that nitric oxide, a chemical messenger involved in bodily functions from erection to nerves' communication, also shuts down a protein involved in Parkinson's disease.

23 Apr 2004