Brain Tumor News and Research

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A Brain Tumor is the growth of abnormal cells in the tissues of the brain. Brain tumors can be benign (not cancer) or malignant (cancer).

Scientists suggest E-cadherin can function as oncogene in some cancers

Researchers at Mayo Clinic in Florida have found that a molecule long believed to be a beneficial tumor suppressor and thus a potential cancer drug target appears to act as an oncogene in some lethal brain tumors.

28 Oct 2010

Antigenics expands HSPPC-96 Phase 2 clinical study in glioma

Antigenics, Inc. today announced the expansion of a phase 2 clinical study of HSPPC-96 (Oncophage® vaccine; vitespen), Antigenics' personalized therapeutic cancer vaccine, in patients with newly diagnosed glioma.

25 Oct 2010

Myrexis to present Phase 2 monotherapy study results of Azixa in patients with GBM

Myrexis, Inc., a biotechnology company focused on discovering, developing, and commercializing novel treatments for cancer, today announced it will present at the 2010 Society for Neuro-Oncology Scientific Meeting and Education Day, to be held November 18-21, 2010 in Montreal, Canada.

22 Oct 2010

Celtic Pharma receives US patent for methods to treat breast, colon cancer

Celtic Pharmaceutical Holdings L.P. today announced that the U.S. Patent Office has issued U.S. patent 7,816,323, for novel methods to treat breast and colon cancers using a combination therapy of Xerecept with Avastin.

22 Oct 2010

Patient-specific experimental vaccine to prevent recurrence of glioblastoma

Mary Lee's primary care physician is also a family friend. When he walked into the exam room in October 2006 with tears in his eyes, she knew something serious was wrong. But she was shocked to learn she had a brain tumor - and later found out it was the most aggressive malignant type, a glioblastoma multiforme.

14 Oct 2010

Teen Art Show shares teenagers' emotions in artistic fashion

With the help of the Child Life Program at St. Jude Children's Research Hospital, 22 new pieces of art were revealed from 19 talented adolescent patients during the Teen Art Show. The artwork is on display in a hospital hallway that was transformed permanently into the Teen Art Gallery.

12 Oct 2010

Family-centered care approach may improve children's care

As physicians and scientists at St. Jude Children's Research Hospital work to find new insights into pediatric cancer and other catastrophic diseases, a central tenant of any treatment plan is to keep families at the center of children's care.

12 Oct 2010

TTF therapy with chemotherapy increases survival time in patients with non-small cell lung cancer

Novocure reported today that patients with advanced non-small cell lung cancer (NSCLC) achieved a significant increase in survival time when tumor treating fields (TTF) therapy was added to chemotherapy, as compared to previously reported outcomes for patients receiving chemotherapy alone.

11 Oct 2010

New approach to provide long lasting relief for headache

Most physicians are treating the symptom of headache using medication. Patients often receive temporary relief from the medication but it does not deal with the cause of the headache. The drug companies are sponsoring research programs to test their drugs in conjunction with most "Headache Facilities."

8 Oct 2010

Role of TGF-ß in cancer diseases

During this year's BIOTECHNICA exhibition, the international biotech news magazine „GEN - Genetic Engineering & Biotechnology News yesterday on 5 October 2010, held an information event with subsequent panel discussion featuring the topic TGF-ß an important target in cancer diseases.

7 Oct 2010

Vaccine improves survival of glioblastoma patients in phase II clinical trial: Researchers

A vaccine that turns the immune system against brain tumor cells bearing a genetic mutation that drives the most aggressive form of glioblastoma multiforme improved survival of patients in a phase II clinical trial, researchers at Duke University and The University of Texas MD Anderson Cancer Center reported today in the Journal of Clinical Oncology.

7 Oct 2010

Lixte, NCI collaborate for clinical evaluation of LB-100 compound

Lixte Biotechnology Holdings announced today that the National Cancer Institute Experimental Therapeutics (NExT) Program Senior Advisory Committee (SAC), Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute (NCI), National Institutes of Health (NIH), signed a NExT Material Transfer Agreement formalizing a collaboration with Lixte Biotechnology Holdings, Inc. for clinical evaluation of LB-100, one of Lixte's lead anti-cancer compounds.

6 Oct 2010

PDGFR gene rearrangements lead to aggressive form of glioblastoma: Study

4 Oct 2010

Activating rearrangements in receptor genes are more common than previously thought

A multi-institutional team led by investigators from Memorial Sloan-Kettering Cancer Center has published a study that provides new insight into genetic changes that make some forms of glioblastoma, the most common type of primary brain cancer, more aggressive than others and explains why they may not respond to certain therapies. The research was led by senior author Eric C. Holland, MD, PhD,--an MSKCC surgeon, researcher and the Director of the Brain Tumor Center--and was published in the October 1 issue of the journal Genes & Development.

1 Oct 2010

American Brain Tumor Association awards $100,000 clinical research grant

The Section on Tumors of the American Association of Neurological Surgeons and Congress of Neurological Surgeons has announced a $100,000 two-year ($50,000/year) clinical research grant funded by the American Brain Tumor Association (ABTA). The application is open exclusively to neurosurgeons who are members of the AANS/CNS Section on Tumors.

30 Sep 2010

Scientists find Alzheimer's Disease reduces human brain cancer growth

Scientists at the Roskamp Institute in Sarasota, Florida, have shown that mice that naturally develop Alzheimer's are able to ward off the growth of brain cancer. In a series of experiments published in the Journal of Neuroscience, they showed that mice that spontaneously develop Alzheimer's Disease are able to dramatically reduce the growth of a human brain cancer.

28 Sep 2010

JAMA issue unveils genetic signature of brain cancer

A pair of studies in the July 15 issue of the Journal of the American Medical Association (JAMA) spell out how much closer science has come to unraveling the genetic signature of brain cancer, according to a researcher at the University of Alabama at Birmingham (UAB).

27 Sep 2010

Gene alteration impacts brain tumor development: Study

The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, according to a study in the July 15 issue of JAMA.

27 Sep 2010

Scientists to develop methotrexate nose drops for brain cancer

Scientists are reporting the development and successful initial testing of a new form of methotrexate the mainstay anticancer drug designed to be given as nose drops rather than injected. It shows promise as a more effective treatment for brain cancer, they say. The report appears in ACS' Molecular Pharmaceutics, a bi-monthly journal.

23 Sep 2010

Revolutionary technology 'cooks' brain tumor

University Hospitals (UH) Case Medical Center is offering new hope for patients with inoperable brain tumors or lesions previously diagnosed as untreatable through a revolutionary technology called AutoLITT which "cooks" brain tumors with an MRI-guided laser. UH becomes one of only three medical centers in the world offering AutoLITT as part of its arsenal in the fight against cancer. It is especially effective in treating glioblastoma, one of the most aggressive and difficult-to-treat brain cancers.

23 Sep 2010