Brown Fat News and Research

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High-fat diets drive the production of inflammatory immune cells in the bone marrow of mice

Scientists have shown that high-fat diets can cause rapid changes in the bone marrow of mice, driving the production of inflammatory immune cells, according to findings published today in eLife.

20 Sep 2022

The brain and fat communicate directly

Researchers examine the sensory innervation of fat cells within subcutaneous fat deposits.

4 Sep 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

Vascular dysfunction may be the cause of metabolic changes that can lead to diabetes, study suggests

A major risk factor for diabetes, insulin resistance occurs when the cells of the body do not respond to insulin and cannot make use of the glucose (sugar) in the blood stream.

5 Aug 2022

Cold exposure could make it harder for cancer cells to grow, mice study shows

Turning down the thermostat seems to make it harder for cancer cells to grow, according to a study in mice by researchers at Karolinska Institutet in Sweden.

3 Aug 2022

Lipids in breastmilk may protect against metabolic disease later in life

A new study examines the lipid content in breastmilk and its association with NCDs later in life.

13 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

Study identifies a molecule that boosts fat burning

A study led by the University of Bonn has identified a molecule - the purine inosine - that boosts fat burning in brown adipocytes.

5 Jul 2022

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet.

29 Apr 2022

Brown adipose tissue is less active in boys with obesity, study finds

A study at McMaster University has found that brown adipose tissue (BAT) is less active in boys with obesity compared to boys with a normal body mass index (BMI).

14 Apr 2022

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

2 Feb 2022

New therapeutic approach offers hope to treat obesity and related metabolic disorders

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new therapeutic approach to obesity and related metabolic disorders that in laboratory experiments demonstrated a significant reduction in body fat, body weight, and improvement in the blood markers that accompany these disorders.

25 Jan 2022

Brown fat could be the key to healthy metabolism in obese people

Not all forms are obesity are the same and brown fat could make all the difference. A study led by Florian Kiefer's research group from the Division of Endocrinology and Metabolism of the Department of Medicine III at MedUni Vienna and Vienna General Hospital shows that people who are seriously overweight (obese) who also have active brown fat have a healthier metabolism and use more energy than obese people without brown fat.

29 Oct 2021

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

27 Oct 2021

COVID-19 vaccine antibodies inversely related to BMI in obese men, but not women

A new study discusses the role of obesity in COVID-19 and its role in antibody-mediated immune responses to the COVID-19 vaccine.

7 Sep 2021

Commonly-used pesticide linked to the global obesity epidemic

A commonly-used pesticide could be partially responsible for the global obesity epidemic, says a study led by McMaster University scientists.

28 Aug 2021

Beige fat cells mediate subcutaneous fat's brain protection from dementia

Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection from dementia.

10 Aug 2021

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

5 Aug 2021

Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis

In a new study published in Circulation Research, Chen-Yu Zhang and Xiaohong Jiang's group from Nanjing University and Dongjin Wang's group from Nanjing Drum Tower Hospital reported a critical role of PGC1α in maintaining the contractile phenotype of vascular smooth muscle cells (VSMCs) and highlighted the therapeutic potential of PGC1α for atherosclerosis.

25 Jun 2021

Researchers discover a new mechanism controlling satiation

Researchers from the Turku PET Centre and Technical University of Munich have discovered a new mechanism controlling satiation. According to the recently published study, the hormone secretin induces satiation by activating brown adipose tissue.

22 Jun 2021