CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

HMS immunologist unravels the mysteries of how the immune system communicates

The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks on the body, both internal and external.

9 Nov 2023

Rise in skin cancer cases underscores importance of early detection using machine learning

Image-processing techniques in machine learning (ML) for skin cancer detection using clinical images.

30 Oct 2023

Current jargon on antibiotic resistance fails to stick or scare, study finds

Researchers find that current terminology related to antimicrobial resistance (AMR) fails to effectively communicate the risks to the public. The study reveals that terms like "AMR" and "antimicrobial resistance" are poorly remembered and do not evoke sufficient risk perception, highlighting the need for improved public health messaging.

29 Oct 2023

Experts warn of 'silent epidemic' of high cholesterol in the UK

The most comprehensive research into cholesterol ever conducted in the UK has found 54% of Brits could have high total cholesterol levels.

28 Oct 2023

Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

27 Oct 2023

Epidemic: What good is a vaccine when there is no rice?

The 1970s was the deadliest decade in the "entire history of Bangladesh," said environmental historian Iftekhar Iqbal

24 Oct 2023

What's really behind the male infertility crisis? New study seeks answers

This comprehensive study in Nature Reviews Urology tackles critical questions in male infertility, from its diagnosis and treatment to its impact on overall health. The review calls for a deeper understanding of male reproductive issues, better diagnostic methods, and improved public and medical awareness of the topic.

15 Oct 2023

Genetically edited chickens show resistance to avian influenza in landmark study

Researchers use CRISPR technology to create chickens resistant to avian influenza, targeting specific genes to inhibit viral replication. The study reveals both the promise and complexities of using genetic editing as a disease control strategy, also shedding light on influenza's adaptability.

11 Oct 2023

Epidemic: Bodies remember what was done to them

Global fears of overpopulation in the '60s and '70s helped fuel India's campaign to slow population growth.

10 Oct 2023

Halting pandemics at the source: The call for a proactive 'One Health' approach

The recent PLoS Pathogens review emphasizes proactively preventing pathogen spillover from animals to humans as a strategy against future pandemics, advocating for a holistic One Health approach that considers the interconnectedness of humans, animals, and the environment. The study underscores the importance of primary prevention, differentiating it from secondary containment, and highlights the economic and societal benefits of preemptive actions over reactive responses.

10 Oct 2023

Harvard neuroscientist seeks to capture synapse-level connectome data from a mouse brain

The human brain is a tangled highway of wires emanating from nearly 100 billion neurons, all of which communicate across trillions of junctions called synapses. "Depressingly complex," Harvard neuroscientist Jeff Lichtman calls it.

9 Oct 2023

UK's first-of-its-kind total-body PET imaging platform could enhance quality and speed of drug discovery

A partnership between Medicines Discovery Catapult (MDC), the Medical Research Council (MRC) and Innovate UK will deliver scientific breakthroughs with the launch of the UK's first-of-its-kind national total-body positron emission tomography (PET) imaging platform for drug discovery

9 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

KFF Health News' 'What the Health?': An encore: 3 HHS secretaries reveal what the job is really like

This week, while KFF Health News' "What the Health?" takes a break, here’s an encore of a favorite episode this year: Host and chief Washington correspondent Julie Rovner leads a rare conversation with the current and two former secretaries of Health and Human Services.

5 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Nicotine e-cigarettes, varenicline, and cytisine most effective for long-term smoking cessation, analysis finds

A comprehensive new analysis has found that nicotine e-cigarettes, varenicline and cytisine are the most effective options currently available for helping smokers quit long-term (going at least six months without smoking).

28 Sep 2023

Deep learning revolutionizes ultra-low-field brain MRI for quicker, clearer scans

Researchers develop a deep learning framework to accelerate ultra-low-field brain MRI, achieving faster scan times and enhanced image quality. The method shows promise in making MRI more accessible and reliable, especially in settings with limited access to high-field scanners.

25 Sep 2023

Has the COVID-19 pandemic widened the mental health gap in the UK?

The study explores the varying mental health impacts of the COVID-19 pandemic on the UK's adult population, revealing increased inequalities and distress. Utilizing both surveys and focus group discussions, the research emphasizes the urgent need for targeted interventions and policy responses to address deteriorating mental health and growing disparities.

24 Sep 2023

Study provides insights into human 8-cell-like cells and early embryonic development

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism.

22 Sep 2023

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Hyperdiploidy is a genetic condition observed in cancer cells, where the cells contain more chromosomes than usual.

20 Sep 2023