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Study uncovers cause of blood-vessel leakiness in eye diseases

Scientists have identified a key step in the process that leads to leaky vessels and harmful swelling in eye diseases, according to a new study published today in eLife.

21 Apr 2020

Researchers solve the riddle of superbug toxin damage to gut

A powerful Monash Biomedicine Discovery Institute (BDI) collaboration has revealed that a bacterial superbug can prevent stem cells in the gut from carrying out their vital role of regenerating the inner lining of the intestine.

16 Mar 2020

'Primitive' stem cells shown to replace and repair damaged blood vessels in the retina

Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes.

9 Mar 2020

BACH1 gene regulator facilitates pancreatic cancer metastasis

A multidisciplinary team of researchers at Japan's Tohoku University has found that a gene regulator, called BACH1, facilitates the spread of pancreatic cancer to other parts of the body.

4 Feb 2020

Study shows how cell competition corrects noisy morphogen gradients during embryogenesis

Tissue patterning is an important process during embryo formation, as well in adult tissue, which ensures that groups of cells are correctly arranged to allow them to function properly.

23 Oct 2019

Cell adhesion protein promotes metastasis in breast cancer, study reveals

Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis.

From Johns Hopkins Medicine 11 Sep 2019

New cellular processes controlling the formation of lymphatic valves found

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms or legs.

28 Aug 2019

Study reveals how basic structure of the brain is formed

The human brain consists of neurons arranged into microscopic columns. The cortex, which is the seat of most cerebral functions and forms the largest part of the brain, is divided into uncountable micro-columns.

23 Jun 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Discovery would help specify role of genetics in the development of neuropsychiatric disorders

Neurobiologists from I.M. Sechenov First Moscow State Medical University confirmed that stress in early age affects the mice with activated and deactivated CDH13 gene in different ways.

27 Nov 2018

Spread of pancreatic cancer to the liver or lungs depends on plasticity of tumor cells

Pancreatic cancer often spreads, forming metastases in the liver or lungs. The prognosis is better for patients with metastases in the lungs.

9 Jul 2018

Vitamin D and Diabetes: What You Need To Know

Dr. Cedric Garland discusses the results of a 12-year cohort study which showed that vitamin D3 can prevent type 1 diabetes in 80 percent of cases.

15 Jun 2018

Study reveals new genetic causes of non-syndromic cleft lip and palate

A study conducted by an international research team, which included investigators from Seattle Children's Research Institute, implicates variants in four genes as a primary cause of non-syndromic cleft lip and palate in humans.

8 Jun 2018

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.

10 Apr 2018

Study contradicts long-established dogma about eye immunity

A person needs immune-suppressive drugs for organ transplants but not typically for transplants in the eye. How come? Like a few other parts of the body, some components of the eye, like the lens, don't have direct access to vessels that deliver immune cells.

27 Jan 2018

Groundbreaking study identifies protein as potential factor in cancer metastasis

U of G scientists have made a discovery that could reduce the spread of cancer by hindering a protein that binds cancer cells together and allows them to invade tissues.

17 Nov 2017

Researchers identify mechanisms through which H. pylori bacteria cause gastric cancer

Gastric cancer is one of the five most fatal types of cancer. According to the statistics of the World Health Organization, about 750,000 patients die each year after developing the disease. The main cause is thought to be the bacterium Helicobacter pylori (H. pylori).

7 Nov 2017

Brazilian scientists examine how benzopyrene can cause cancer

Benzo[a]pyrene is a potent carcinogen and mutagen present in cigarette smoke, automotive exhaust, burnt wood fumes, barbecued and smoked meat etc.

23 Oct 2017

Researchers use gene therapy to restore hearing and balance in mouse model of Usher syndrome

Hearing loss, sometimes associated with other disorders such as balance defects, is the most common sensory deficit, affecting more than 280 million people worldwide, according to WHO. In France, one child in 700 is born with severe or profound hearing loss, and one in every 1,000 will lose their sense of hearing before adulthood.

22 Sep 2017

Scientists uncover mechanism that keeps cells in the right places

Scientists have uncovered how cells are kept in the right place as the body develops, which may shed light on what causes invasive cancer cells to migrate.

26 Jul 2017