Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.
One common gut organism that helps us digest food better could also be a powerful instrument in preventing or reversing the symptoms of Parkinson’s disease (PD), according to a recent study. The changes are due to the ability of this bacterium to delay the build-up of a toxic protein involved in this in the disease condition, or even to eliminate the toxin altogether.
Researchers at Worcester Polytechnic Institute have developed a tool to identify molecular receptors in worms that are involved in sensing pheromones related to mating, an advance that could speed up neuroscience research into pheromones by eliminating months of work.
Researchers at Harvard Medical School and the New York State Department of Health have discovered how a common plasticizer associated with human reproductive abnormalities likely does its damage at the molecular level.
Uniting structure and function of synapses is challenging: Function is studied in living tissue, measuring electrical signals at millisecond precision with electrophysiology, while the observation of fine structure at nanometer scale requires tissue to be fixed for electron microscopy.
A study by researchers in the United States and India has shown that probiotic yeasts derived from food are able to reduce the virulence of, and even prevent infections by, several types of fungi that are responsible for life-threatening infections in hospitalized and immune-compromised individuals, including the multi-drug resistant Candida auris, which was recently listed as an urgent threat by the U.S. Centers for Disease Control in its 2019 Antibiotic Resistance Threats report.
Insights from their study may provide a novel therapeutic approach for diseases such as Huntington's and Parkinson's.
A team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.
The brain's neural activity-;long implicated in disorders ranging from dementia to epilepsy-;also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School.
Most people have some idea of how important iron is to their health, but Iqbal Hamza, professor in Animal and Avian Sciences, has made his seventeen-year career at the University of Maryland all about the study of iron and heme trafficking and regulation in the body.
Every day, people are exposed to myriad chemicals, both natural and synthetic. Some of these compounds may affect human physical development, but testing them directly on people would be grossly unethical.
Researchers at the Max Delbrueck Center for Molecular Medicine have identified an epigenetic mechanism that appears to strongly influence healthy aging.
EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.
Aging research indicates that better healthspan--the quality of life as we age--may be more important than lifespan.
In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism.
Over one billion people, including 880 million children, are infected with intestinal nematode worms, such as roundworms, hookworms and tapeworms, according to the World Health Organization.
Muscle decline caused by aging and certain diseases could be dramatically slowed by stopping a chain reaction that damages cells, new research shows.
Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.
An international research collaboration that includes the University of Arkansas for Medical Sciences has discovered that aging in nematodes (worms) can be slowed and even reversed by a number of Food and Drug Administration-approved drugs, findings that have the potential to extend human lifespan.
A new Cornell University-led study finds that the genome for a widely researched worm, on which countless studies are based, was flawed. Now, a fresh genome sequence will set the record straight and improve the accuracy of future research.
Researchers from Gero, Skolkovo Institute of Science and Technology, Moscow Institute of Physics and Technology, and University of Arkansas for Medical Sciences collaborated to derive a transcriptomic signature of aging, which they confirmed using large transcriptomic databases.