Calcitriol News and Research

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Calcitriol is a form of Vitamin D3 with three alcohol groups. It increases gastrointestinal calcium absorption, stimulates osteoclastic calcium resorption from bone, facilitates the effect parathyroid hormone (PTH) has on bone resorption, and increases renal tubular absorption of calcium. Production of calcitriol by the cells of the proximal tubule of the nephron in the kidney is stimulated by hypocalcemia and hypophosphatemia as well as parathyroid hormone.

$Study suggests Vitamin D prescription lowers hip fracture incidence$

Study suggests Vitamin D prescription lowers hip fracture incidence

Researchers examined the relationship between vitamin D supplementation and osteoporosis-related fracture incidence.

14 Aug 2023

Link found between vitamin D deficiency and metabolic abnormalities in children: New insights unveiled

Researchers investigated the correlation between vitamin D deficiency and metabolic syndrome (MetS) components.

8 Aug 2023

The immunomodulatory and antiviral function of vitamin D

Vitamin D's immunomodulatory and antiviral function.

4 Aug 2023

Vitamin D supplementation reduces risk of major cardiovascular events in older adults

Research investigates the impact of vitamin D supplementation on the incidence of major cardiovascular events in older adults. It examines whether monthly doses of vitamin D can alter the occurrence of heart-related problems.

4 Jul 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Experts provide first framework for treating hypercalcemia of malignancy in adults

Experts provide the first framework for treating a common and life-threatening metabolic complication of cancer known as hypercalcemia of malignancy in the Endocrine Society's new Clinical Practice Guideline.

21 Dec 2022

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through drinking water.

16 Dec 2022

Does vitamin D reduce COVID-19 severity?

A new study examined published studies for a consistent association between vitamin D levels and coronavirus disease 2019 (COVID-19) severity.

8 Nov 2022

Dispensing of hydroxychloroquine and ivermectin in Australia jumped in first year of COVID

A new study describes the nature and extent of the shift in dispensing these medications, as well as its eventual outcome.

3 Oct 2021

Can Vitamin D help combat the coronavirus?

In a new report published in The Lancet, a team of researchers discussed the possibility that vitamin D could offer protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The meta-analyses of randomized controlled trials performed from 2007 to 2020.

4 Aug 2020

Researchers show how upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Does vitamin D deficiency increase COVID-19 risk?

A new paper published on the preprint server medRxiv* in May 2020 reports the first evidence that vitamin D deficiency and inadequate treatment could increase the chances of testing positive for COVID-19. This could shape the way for screening individuals at risk for vitamin D deficiency.

14 May 2020

Too much vitamin D may reduce bone density, say scientists

Excessive supplementation with vitamin D can cause bone loss and bone weakening, according to a new study.

6 Sep 2019

Vitamin D metabolite may stop mechanism by which cancer cells become drug-resistant

What's good for our bones may also help stop cancer cells that develop resistance to multiple chemotherapy drugs.

14 Jun 2019

Inherited form of rickets improves more with new injectable medicine than conventional therapy

Burosumab, a new injectable medicine to treat X-linked hypophosphatemia (XLH), an inherited form of rickets, demonstrates superior improvements in rickets and other outcomes compared with conventional therapy in an international, phase 3 clinical trial in children.

25 Mar 2019

Study opens new potential avenue for treating ovarian cancer

Researchers at Houston Methodist Research Institute and The University of Texas MD Anderson Cancer Center have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer.

14 Jun 2018

Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

The length of your telomeres appears to be a window into your heart health and longevity, and scientists are measuring them to see if vitamin D and omega-3 supplements really improve both.

14 Nov 2016

Low levels of vitamin D, methylation in black teens may increase cancer risk

Low levels of vitamin D in black teens correlates with low activity of a major mechanism for controlling gene expression that may increase their risk of cancer and other disease, researchers report.

26 Apr 2016

Adding CYP24A1 inhibitors may improve antitumor activity of vitamin D

Roswell Park Cancer Institute research on the most potent form of vitamin D, commonly called calcitriol, offers new insights into approaches that may enhance the antitumor activity of this much-studied human hormone.

20 Apr 2016

Chronic heart failure patients with decreased calcitriol may benefit from aggressive supplementation

In patients with chronic heart failure, the vitamin D metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D), also called calcitriol, and its ratio to parathyroid hormone (PTH 1-84) may help predict cardiovascular death; and patients with decreased calcitriol and decreased ratio of calcitriol to PTH might benefit from more aggressive supplementation, a new study finds.

9 Mar 2015