Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, today announced that an interim analysis of all 86 patients enrolled in the company's Phase 2b RESTORE-CLI clinical trial shows that the study achieved both its primary safety endpoint and primary efficacy endpoint of time to first occurrence of treatment failure.

19 Nov 2010

LVNC cardiomyopathy associated with heart failure, stroke and ventricular arrhythmias

Left ventricular non-compaction (LVNC), a cardiomyopathy about which little is fully understood, is associated with heart failure (HF), stroke and ventricular arrhythmias, according to a study to be presented Nov. 17 at the 2010 American Heart Association (AHA) Scientific Sessions in Chicago. The researchers also will report that advanced imaging technologies reveal that developing these cardiac risks appear to progress over time in patients with LVNC.

18 Nov 2010

Cardiac stem cells from sick patients could generate new heart muscle: Research

Cardiac stem cells even in elderly and sick patients could generate new heart muscle and vessel tissue and be used to treat heart failure, according to research presented at the American Heart Association's Scientific Sessions 2010.

18 Nov 2010

PGxHealth presents results from studies using FAMILION genetic testing at 2010 AHA

Clinical Data, Inc., today announced that results of studies using its FAMILION® genetic testing were presented at the 2010 American Heart Association (AHA) meeting. PGxHealth, a division of Clinical Data, together with its collaborators, presented results from the largest, most comprehensive studies of genetic variation associated with certain cardiac conditions that were revealed using FAMILION testing.

15 Nov 2010

Hydroxychloroquine may reduce cardiac neonatal lupus in subsequent pregnancies: Research

Women with anti-SSA/Ro antibodies and a previous child who has heart block a condition where the electrical signal that makes the heart beat is damaged may potentially decrease their risk of delivering another child with life threatening heart disease by taking hydroxychloroquine (Plaquenil), according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

SPRYCEL receives FDA approval for treating adult patients with Ph+ CML in chronic phase

After receiving a priority review, Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co., Ltd. today announced that the U.S. Food and Drug Administration (FDA) has approved SPRYCEL (dasatinib) 100 mg once daily for the treatment of adult patients with newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in chronic phase.

29 Oct 2010

Aastrom Biosciences and ATEK Medical enter new strategic partnership

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, and ATEK Medical, a leading medical device manufacturer, today announced the formation of a new strategic partnership in which ATEK Medical will supply key components and technology for use in Aastrom's proprietary cell manufacturing process.

26 Oct 2010

miRagen and CU enter agreement on miRNA therapeutics discovery and development

miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients' lives by developing innovative microRNA (miRNA)-based therapeutics for cardiovascular and muscle disease, and the University of Colorado (CU) announced today that they have entered into sponsored research and licensing agreements to collaborate on miRNA therapeutics discovery and development.

26 Oct 2010

Genetic code of sudden death cardiac killer cracked

Researchers in Newfoundland have cracked the genetic code of a sudden death cardiac killer.

26 Oct 2010

Aastrom submits SPA for Phase 3 clinical development program in critical limb ischemia to FDA

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, today announced that it has submitted to the U.S. Food and Drug Administration (FDA) a special protocol assessment (SPA) describing the company's proposed Phase 3 clinical development program in critical limb ischemia (CLI).

21 Oct 2010

Beaumont Hospital announces opening of new Ernst Cardiovascular Center

Beaumont Hospitals' world renowned heart center has expanded and enhanced its services with the Oct. 18 opening of the new Ernst Cardiovascular Center at Beaumont Hospital, Royal Oak.

21 Oct 2010

FDA grants fast track designation for Aastrom's CLI cell therapy development program

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, today announced that the U.S. Food & Drug Administration (FDA) has granted fast track designation for the company's critical limb ischemia (CLI) cell therapy development program. Aastrom plans to initiate Phase 3 clinical testing of its treatment for CLI in early 2011.

18 Oct 2010

SynCardia Total Artificial Heart provides 'unexpected' 1,000 days of life

A 54-year-old Italian man has become the first patient to surpass 1,000 days of support with the SynCardia temporary Total Artificial Heart while waiting for a matching donor heart.

12 Oct 2010

Survey shows obstetricians, gynecologists unfamiliar with Chagas' disease

According to recent survey results published in the October issue of The American Journal of Tropical Medicine and Hygiene, obstetricians and gynecologists in the United States are unfamiliar with Chagas' disease, a condition that affects an estimated 300,000 people in the United States and can cause serious cardiovascular and digestive complications.

8 Oct 2010

ARCA receives European Patent for bucindolol based treatment for heart failure

ARCA biopharma, Inc. a biopharmaceutical company developing genetically-targeted therapies for heart failure and other cardiovascular diseases, today announced that the European Patent Office has issued a patent on methods of treating heart failure patients with bucindolol based on genetic targeting.

8 Oct 2010

UCLA-led consortium receives $9.9M to compare wireless and telephone management after hospitalizations

A UCLA-led consortium of five University of California medical schools, plus Cedars-Sinai Medical Center in Los Angeles, has received $9.9 million from the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality to research the use of wireless and telephone care management to reduce hospital readmissions for heart failure patients.

6 Oct 2010

Healthcare organizations urge Congress to raise awareness on sudden cardiac arrest

In a powerful demonstration of collective standing in the health care community, more than 40 organizations gathered on Capitol Hill to issue a call to action in reducing sudden cardiac arrest (SCA) deaths.

6 Oct 2010

Merck's boceprevir Phase III studies for HCV to be presented at 61st AASLD

Merck today announced that final results from two pivotal Phase III studies of boceprevir, its investigational oral hepatitis C protease inhibitor, will be presented in oral plenary sessions at the 61st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), which is taking place from Oct. 29 through Nov. 2 in Boston. Results for boceprevir in response-guided therapy strategies, which evaluated treatment durations shorter than current standard therapy, will be presented during the meeting.

4 Oct 2010

Mandatory ECG screening for athletes

Should athletes have to undergo mandatory electrocardiographic screening (also known as ECG or heart trace) before competing? Doctors debate the issue in this week's BMJ.

4 Oct 2010

Study indicates garlic could help prevent cardiomyopathy

Garlic has significant potential for preventing cardiomyopathy, a form of heart disease that is a leading cause of death in people with diabetes, scientists have concluded in a new study. Their report, which also explains why people with diabetes are at high risk for diabetic cardiomyopathy, appears in ACS' bi-weekly Journal of Agricultural and Food Chemistry.

30 Sep 2010

Cardiomyopathy News and Research

Further Reading

Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

LVNC cardiomyopathy associated with heart failure, stroke and ventricular arrhythmias

Cardiac stem cells from sick patients could generate new heart muscle: Research

PGxHealth presents results from studies using FAMILION genetic testing at 2010 AHA

Hydroxychloroquine may reduce cardiac neonatal lupus in subsequent pregnancies: Research

SPRYCEL receives FDA approval for treating adult patients with Ph+ CML in chronic phase

Aastrom Biosciences and ATEK Medical enter new strategic partnership

miRagen and CU enter agreement on miRNA therapeutics discovery and development

Genetic code of sudden death cardiac killer cracked

Aastrom submits SPA for Phase 3 clinical development program in critical limb ischemia to FDA

Beaumont Hospital announces opening of new Ernst Cardiovascular Center

FDA grants fast track designation for Aastrom's CLI cell therapy development program

SynCardia Total Artificial Heart provides 'unexpected' 1,000 days of life

Survey shows obstetricians, gynecologists unfamiliar with Chagas' disease

ARCA receives European Patent for bucindolol based treatment for heart failure

UCLA-led consortium receives $9.9M to compare wireless and telephone management after hospitalizations

Healthcare organizations urge Congress to raise awareness on sudden cardiac arrest

Merck's boceprevir Phase III studies for HCV to be presented at 61st AASLD

Mandatory ECG screening for athletes

Study indicates garlic could help prevent cardiomyopathy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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