Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

Surgeons at NYU Langone Health performed the first combined mechanical heart pump and gene-edited pig kidney transplant surgery.

24 Apr 2024

New models improve heart disease risk prediction, especially for women

When it comes to matters of the heart, cardiovascular disease in women is underdiagnosed compared to men. A popular scoring system used to estimate how likely a person is to develop a cardiovascular disease within the next 10 years is the Framingham Risk Score. It is based on factors including age, sex, cholesterol levels, and blood pressure.

23 Apr 2024

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Dilated cardiomyopathy is the most frequent cause of heart failure in young people and is the leading cause of heart transplantation. In this disease, the heart enlarges and reduces its capacity to pump blood. People with dilated cardiomyopathy are at high risk for arrhythmias and sudden death.

22 Apr 2024

Lifetime risk of atrial fibrillation rises to nearly 31% in recent decade

The risk of both AF and its complications in a Danish national cohort, beginning from the age of 45 years.

17 Apr 2024

Chronic low-level inflammation may be a contributor to both depression and heart disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital have found.

8 Apr 2024

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with evidence of improvements in symptoms and exercise capacity among people with nonobstructive hypertrophic cardiomyopathy (HCM), according to results of a 12-week phase 2 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment in patients who were not taking SGLT2 inhibitors or GLP-1 RAs, which are antidiabetic medications that also have benefits for the heart.

8 Apr 2024

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

The first randomized trial to investigate preventive ablation of a potential arrhythmogenic substrate associated with coronary chronic total occlusion (CTO) in patients at high risk of ventricular arrhythmias (VAs) reduces the risk of appropriate implantable cardioverter-defibrillator (ICD) therapy and unplanned hospitalization in patients with no previously recorded VAs.

8 Apr 2024

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).

8 Apr 2024

Interatrial shunt may offer differential benefits based on heart failure type

Patients with heart failure who had a small shunt inserted between the heart's left and right atria did not see any significant benefits overall compared with those who received a placebo procedure after a median of 22 months follow-up, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

New research advocates genetic screening in early onset atrial fibrillation

Although the vast majority of clinicians do not view atrial fibrillation (AF) as a genetic disorder, a White Paper in the Canadian Journal of Cardiology, published by Elsevier, analyzes the current understanding of genetics and the role of genetic testing in AF and concludes there is an increasing appreciation that genetic culprits for potentially life-threatening ventricular cardiomyopathies and channelopathies may initially present with AF.

28 Mar 2024

Study links long-term ADHD stimulant use to increased risk of cardiomyopathy

Young adults who were prescribed stimulant medications for attention-deficit/hyperactivity disorder (ADHD) were significantly more likely to develop cardiomyopathy (weakened heart muscle) compared with those who were not prescribed stimulants, in a study presented at the American College of Cardiology's Annual Scientific Session.

27 Mar 2024

Hidden brain changes found to be common in people with a range of heart conditions

A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.

26 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Cardiomyopathy News and Research

Further Reading

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

New models improve heart disease risk prediction, especially for women

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Lifetime risk of atrial fibrillation rises to nearly 31% in recent decade

Chronic low-level inflammation may be a contributor to both depression and heart disease

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

Interatrial shunt may offer differential benefits based on heart failure type

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

New research advocates genetic screening in early onset atrial fibrillation

Study links long-term ADHD stimulant use to increased risk of cardiomyopathy

Hidden brain changes found to be common in people with a range of heart conditions

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

SARS-CoV-2-associated ARDS can damage the heart without direct infection

Lower income and education levels increase risk of alcohol-related medical conditions

The efficacy of the Mediterranean diet on health outcomes in adults with cancer

Childhood cancer survivors rarely up to date for recommended surveillance tests

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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