Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Improved cell therapy for cartilage repair

Artificially cultured cartilage cells, grown outside of the body for reparing damaged tissue, prove to be different from original cartilage tissue.

2 Dec 2006

New treatment for lower back pain using patient's own stem cells

A University of Manchester researcher has developed a treatment for lower back pain using the patient's own stem cells, which could replace the use of strong painkillers or surgery that can cause debilitation, neither of which addresses the underlying cause.

From The University of Manchester 2 Dec 2006

Acupuncture and Turmeric could be viable treatment options for arthritis sufferers

People who suffer from osteoarthritis (OA) as a rule find it has to varying degrees an impact on their mobility and quality of life.

31 Oct 2006

Gene mutation explains type of brittle bone disease

A newly identified gene mutation helps explain a subset of cases of osteogenesis imperfecta (OI), or brittle bone disease, whose origin had until now remained mysterious.

20 Oct 2006

Arthrosurface launches new product for treatment of patello-femoral disease

Arthrosurface has received FDA clearance to launch its cartilage surface implant system for the treatment of patello-femoral disease.

15 Aug 2006

Atp7a determines a hierarchy of copper metabolism essential for notochord development

A new study reveals the timing of developmental events that critically depend on copper. While copper deficiency is rare in humans, the findings suggest that suboptimal copper metabolism might contribute to birth defects, according to the researchers.

8 Aug 2006

New faster magnetic resonance imaging (MRI) data-acquisition technique

A faster magnetic resonance imaging (MRI) data-acquisition technique will cut the time many patients spend in a cramped magnetic resonance scanner, yet deliver more precise 3-D images of their bodies.

26 Jul 2006

Estradiol and its metabolites and their association with knee osteoarthritis

Osteoarthritis, which usually develops between the ages of 40 and 50, is more prevalent in women. It is thought that sex hormones may play a role in developing the disease, since they can be involved in inflammation of the tissues affected by it.

26 Jul 2006

Disease-specific gene expression profiles in patients with rheumatoid arthritis

They sleep together, eat together, and most people find it impossible to tell them apart. Identical twins who grow up together share just about everything, including their genes.

26 Jul 2006

Loss of Matrilin-3 gene leads to osteoarthritis

A gene that is associated with osteoarthritis and skeletal deformities in people has been shown to be responsible for preventing the onset of osteoarthritis in adult mice, according to a recent study led by Rhode Island Hospital.

24 Jul 2006

Bioengineered tissue implants regenerate damaged knee cartilage

Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.

5 Jul 2006

Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees

Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.

4 Jul 2006

Stem cell breakthrough

Researchers at The Hospital for Sick Children (SickKids) and the University of Calgary have found that stem cells derived from adult skin can create neural cell types that can be transplanted into and function in mouse models of disease.

14 Jun 2006

MicroCT-based virtual histology

Utah and Texas researchers combined miniature medical CT scans with high-tech computer methods to produce detailed three-dimensional images of mouse embryos - an efficient new method to test the safety of medicines and learn how mutant genes cause birth defects or cancer.

8 May 2006

DARPA grant supports research toward realizing tissue regeneration

While U.S. soldiers fighting in Iraq and Afghanistan are surviving injuries that in previous conflicts likely would have been fatal, the number of wounded with major tissue loss has never before been so high.

3 May 2006

Cellular events leading to chondrocyte death after cartilage impact injury

Documented in extensive studies, backed by the anecdotal evidence of professional athletes, impact injury to joints causes degeneration of cartilage.

3 May 2006

Swedish ACI method of cartilage repair gives excellent durability

As the population ages, arthritis will become more prevalent. It would be helpful to know more about the causes and treatments of cartilage wear.

25 Apr 2006

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.

16 Apr 2006

Statins may be able to play a role in preventing or slowing heart valve disease

Research to be published in the April 18 issue of the Journal of the American College of Cardiology provides the first explanation of an active rather than passive process that leads to heart valve degeneration, furthering a Northwestern researcher's effort to lead a paradigm shift in the medical community's beliefs about the cause of valve disease.

11 Apr 2006

Lubricin research points to future therapies for osteoarthritis

New evidence to explain how the body's natural joint lubricant prevents the wear and tear that can lead to osteoarthritis has been uncovered by researchers at Duke University's Pratt School of Engineering.The findings may lead to new methods for treating arthritis, the researchers said.

11 Apr 2006