Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Overlapping signals in embryo help get the backbone right

A major step in the development of the vertebrate embryo - the establishment of a back that morphs into a brain, spinal cord and muscles - turns out to be so important that the body uses at least three signals to make sure it happens properly.

9 Mar 2005

Scientists gain new insight into DiGeorge syndrome

A collaboration of European scientists has uncovered new insight into the most common chromosomal microdeletion syndrome in humans.

28 Feb 2005

Surgical treatment of hip or knee arthritis does not reduce obesity

A number of arthritis sufferers attribute their weight gain to inactivity due to a painful hip or knee. These patients may be disheartened when their post-operative weight either remains the same or increases.

27 Feb 2005

Ankle sprains may predispose a patient to osteoarthritis

Ankle sprains may predispose a patient to osteoarthritis according to a study presented at the American Orthopaedic Foot and Ankle Society’s Annual Winter Meeting in Washington, DC.

27 Feb 2005

Measuring hyaluronan in joints and fluid that lubricates cartilage might enable doctors to diagnose osteoarthritis more accurately

Measuring a biological chemical called hyaluronan found naturally in joints and the fluid that lubricates cartilage might enable doctors to diagnose osteoarthritis of the knee and hip earlier or more accurately, a new study concludes.

27 Feb 2005

New imaging technology may serve as objective outcome measures for orthopedic conditions

New imaging technologies are enabling doctors to not only diagnose a variety of orthopaedic and musculoskeletal conditions with more accuracy, but also to determine with unprecedented precision whether clinical recovery from bone, joint or tendon damage is actually complete and not simply a "placebo effect."

27 Feb 2005

$Osteochondral allograft and microfracture procedures restore patient mobility$

Osteochondral allograft and microfracture procedures restore patient mobility

Two separate new studies presented at a major medical meeting provide objective scientific evidence that the two most commonly performed cartilage repair techniques are effective at restoring patient mobility and reducing pain.

24 Feb 2005

First implant of cryopreserved osteoarticular allograft

CryoLife, a biomaterials and biosurgical device company, announced today that a patient received the first Cryopreserved osteoarticular (OA) allograft transplant for resurfacing articular cartilage in the knee.

23 Feb 2005

Lack of collagen increases likelihood of osteoarthritis

Duke University Medical Center researchers have found that joints whose cartilage lacks a specific type of collagen will develop osteoarthritis – the so-called "wear-and-tear" form of the disease – at a greatly accelerated rate.

20 Feb 2005

New bone marrow model could help people with sickle cell disease

A new model showing how sickle cell blood cells operate within bone marrow is presented at a conference in Austria today. Researchers at Imperial College London, who developed the model, hope that it will eventually be used by clinicians to advance more effective treatments for sickle cell disease.

20 Feb 2005

Achieva 3T MR Scanner launched officially launched

The first 'next generation' MRI (magnetic resonance imaging) body scanner in the world will be officially launched at Hope Hospital later this week (Friday 18th February).

15 Feb 2005

Mesoblast signs adult stem cells agreement

Australia’s adult stem cell company, Mesoblast Limited, today announced that it had signed an agreement for production of specialised adult stem cells, known as Mesenchymal Precursor Cells (MPCs), to be used in human pilot clinical trials in patients with orthopaedic and cardiovascular diseases.

14 Feb 2005

Study sheds light on growing pains and growth spurts

The existence of growth spurts and growing pains in children may be perpetually evident to parents, but their cause has lacked scientific explanation. A new study by Emory University anthropologist Michelle Lampl, M.D., Ph.D., and colleagues at the University of Wisconsin-Madison now sheds some light on this childhood phenomena.

13 Feb 2005

Researchers have discovered an ample source of stem cells in an uncharted part of the umbilical cord

The study, published in the February issue of Stem Cells, outlines how researchers discovered that the jelly-like connective tissue surrounding the blood vessels of the human umbilical cord, the so-called "Wharton's Jelly," is rich in mesenchymal progenitor cells – cells that generate bone, cartilage and other tissues – and can be harvested to generate an abundant supply in a short amount of time.

9 Feb 2005

Gene therapy helps generate bone around dental implants

A University of Michigan research team has found that introducing a growth factor protein into a mouth wound using gene therapy helped generate bone around dental implants, according to a new paper in the February issue of the journal Molecular Therapy.

3 Feb 2005

Aastrom Biosciences responds to article regarding contaminated stem cell lines

Aastrom Biosciences responded today to the publication in the Sunday online edition of Nature Medicine of findings by California researchers that indicate that certain lines of human embryonic stem cells have been contaminated through the use of mice feeder cells.

25 Jan 2005

Breakthrough technology which will allow tailor-made tissues and bones to be grown

Made-to-measure skin and bones, which could be used to treat burn victims or patients who have suffered severe disfigurements, may soon be a reality using inkjets which can print human cells.

From The University of Manchester 20 Jan 2005

Strong association between high levels of hyaluronic acid and severe osteoarthritis

A chronic degenerative joint disease, osteoarthritis (OA) is a common cause of pain and disability among older Americans. OA of the knee affects up to 6 percent of the older population, while OA of the hip affects about another 3 percent. While treatments vary, there is hope that early intervention – before joint destruction can be clearly seen and measured on an X-ray image-will improve outcomes.

7 Jan 2005

Signaling molecule involved in osteoarthritis identified

Using naturally-occurring mutant mice with a defective collagen gene, scientists at Harvard have identified a signaling molecule involved in one of the most common causes of disability among the elderly in the United States, osteoarthritis.

4 Jan 2005

New gel promotes healing by gluing bone pieces together

A new material that fuses biological and synthetic substances at the molecular level speeds bone and cartilage repair. Its creators at the Technion-Israel Institute of Technology say laboratory studies have shown the new gel promotes healing by gluing bone pieces together and stimulating tissue development.

26 Dec 2004