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New technology based on moths and magnets could help treat genetic diseases

A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic fibrosis.

14 Nov 2018

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

While it has long been recognized that mutated gene NPM1 plays an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.

13 Nov 2018

Researchers discover possible path forward in preventing cancers tied to two viruses

Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis--more commonly known as mono or the "kissing disease"--that infects millions of people around the globe each year.

12 Nov 2018

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off."

8 Nov 2018

New research to understand fundamental role of ubiquitin in cell death or survival

An effective regulation of programmed cell death is crucial for the correct development of embryos, a working innate immune system, and the prevention of cancer. How cells control the switch between cell survival and death, and which signaling pathways are involved, remain unclear.

8 Nov 2018

Researchers examine immune responses to CRISPR-Cas9 gene editing system

The CRISPR-Cas9 gene editing system has been generating excitement within the field of gene therapy, inspiring hopes of molecular tools capable of treating genetic diseases.

30 Oct 2018

Using genome editing to prevent sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people.

30 Oct 2018

Study suggests new strategy to kill melanoma cells

Think of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that most cancer cells have found ways to remove this "finger" - commonly, by breaking the action of a gene called p53 that puts the BH3 finger in motion. Now think of Bcl-2 as the switch itself.

24 Oct 2018

How a single mutation can devastate cellular function

A scientist has shown how a single mutation in a protein found in astrocytes reproduces fibrous globs that devastate cellular function.

23 Oct 2018

IDT to demonstrate CRISPR expertise at European-focused events

As an advocate for the genomics age, Integrated DNA Technologies (IDT), will showcase its renowned CRISPR expertise at a series of European-focused events.

From Integrated DNA Technologies 22 Oct 2018

A new approach identified to control Zika virus, dengue fever

Mosquitoes are the world's deadliest animals, killing thousands of people and causing millions of illnesses each year.

19 Oct 2018

Genetically modifying zebrafish provides numerous, highly accurate disease models

Research published today describes how zebrafish can be genetically engineered to produce more accurate models of human disease.

18 Oct 2018

Researchers to study the use of CRISPR on human liver on-a-chip platform

Two Arizona State University professors are among the first recipients of Somatic Cell Genome Editing grants from the National Institutes of Health Common Fund. The $2,600,000, five-year grant will fund the first study of the genome editing technology CRISPR to be used on a "human liver on-a-chip" platform.

15 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

Brown researchers uncover new clues about ALS progression

Brown University researchers have uncovered new clues about the progression of Amyotrophic Lateral Sclerosis (ALS), a surprisingly common disease that causes the death of motor neurons that control voluntary muscles such as those involved in walking, talking, chewing or breathing.

10 Oct 2018

New research projects aim to stop spread of African swine fever and prevent outbreak in the U.S.

African swine fever virus threatens to devastate the swine industry and is positioned to spread throughout Asia. The virus has spread throughout the Caucuses region of Eastern Europe and was reported in China in August. It recently was detected in wild boar in Belgium.

10 Oct 2018