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Cellular IPOD plays role in prion biology

Cells take advantage of a biologically ancient compartment to sequester prions, an action that can initially prevent the prions’ phenotypic expression, according to Whitehead Institute researchers. While in this compartment, less heritable prion plaques mature to a more transmissible state.

27 Apr 2010

Alnylam Pharmaceuticals publishes encouraging results from Phase II GEMINI study in PNAS

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has published results from its Phase II GEMINI study in the Proceedings of the National Academy of Sciences (PNAS). These data, previously presented at the International Symposium on Respiratory Viral Infections in Singapore in 2008, showed human proof of concept with an RNAi therapeutic in a randomized, double blind, placebo-controlled study.

27 Apr 2010

Interim results from Phase I clinical trial of PLX-PAD for treatment of CLI

Pluristem Therapeutics Inc. today announced interim top-line results from its Phase I clinical trials utilizing its placenta-derived cell therapy product, PLX-PAD, for the treatment of critical limb ischemia, the end-stage of peripheral artery disease. The interim data demonstrated that PLX-PAD is safe, well tolerated and effective.

27 Apr 2010

Pluristem Therapeutics to raise $2.7M through private placement of restricted common stock

Pluristem Therapeutics Inc. today announced that it has entered into definitive agreements with selected investors to sell restricted common stock and warrants for aggregate gross proceeds of approximately $2.7 million. The offering includes 2,420,293 shares of common stock, warrants to purchase 726,088 shares of common stock at an exercise price of $1.25 per share and warrants to purchase 726,088 shares of common stock at an exercise price of $1.40 per share.

27 Apr 2010

Compugen reports revenues of $125,000 for first-quarter 2010

Compugen Ltd. today reported financial results for the first quarter ending March 31, 2010.

27 Apr 2010

MMC announces acquisition of BGR.com

Mail.com Media Corporation, the digital media company that owns and operates the Mail.com portal and email service as well as a growing portfolio of lifestyle brands including, Deadline.com, HollywoodLife.com, Movieline.com and OnCars.com, announced today its acquisition of BGR.com, one of the top mobile/gadget sites in the world.

27 Apr 2010

Prime-boost malaria vaccine regimen provides sterile protection: Vical

Vical Incorporated announced today that a prime-boost malaria vaccine regimen provided sterile protection, with no disease symptoms and no detectable malaria parasites, in 4 of 15 vaccinated volunteers a full 28 days after challenge with multiple infected-mosquito bites.

27 Apr 2010

Protalix BioTherapeutics submits validation data for taliglucerase alfa manufacturing process to the FDA

Protalix BioTherapeutics, Inc., announced today it has submitted validation data regarding the Company's manufacturing process for taliglucerase alfa to the U.S. Food and Drug Administration (FDA). The Company made the submission in response to a request from the FDA for validation data from the Company's upgraded manufacturing facility. The FDA is currently reviewing the Company's New Drug Application (NDA) for taliglucerase alfa for the treatment of Gaucher disease.

27 Apr 2010

MicroStockProfit.com announces investment report featuring BioElectronics

MicroStockProfit.com announces an investment report featuring BioElectronics Corp. The report includes financial, comparative and investment analyses, and industry information you need to know to make an educated investment decision.

27 Apr 2010

Illumina announces shipment of HiScanSQ system for research needs

Illumina, Inc. today announced shipment of HiScanSQ, the first instrument to integrate microarray analysis and next-generation sequencing in a modular design that can evolve with changing research needs.

From Illumina, Inc. 27 Apr 2010

Cell phone program to promote more physical activity

About two thirds of the American population is overweight or obese, putting them at higher risk for health problems such as heart disease, stroke, cancer and diabetes. The obesity epidemic in America is the result of poor eating habits, genetics, and a lack of exercise. It's therefore difficult for public health officials to get people to make a conscious effort to control their weight.

27 Apr 2010

Pericytes may use mechanical forces to initiate angiogenesis: Researchers

Pericytes, the contractile cells surrounding capillaries, may use mechanical forces to initiate angiogenesis, the "sprouting" of new blood vessels, according to researchers at Tufts University School of Medicine and the Massachusetts Institute of Technology.

27 Apr 2010

Slitrk5 gene linked to development of OCD-like behaviors

Researchers at the Ansary Stem Cell Institute and the Department of Psychiatry at Weill Cornell Medical College discovered that mice missing a single gene developed repetitive obsessive-compulsive-like behaviors. The genetically altered mice, which behaved much like people with a certain type of obsessive-compulsive disorder (OCD), could help scientists design new therapies for this debilitating condition.

27 Apr 2010

Researchers identify molecular marker of pancreatic cancer

Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a molecular marker of pancreatic cancer that may help spot the disease at its earliest stages, when it can be treated more successfully with surgery.

27 Apr 2010

Vital stem cells extracted during heart bypass surgery can help repair damaged heart muscle: BHF

Scientists have for the first time succeeded in extracting vital stem cells from sections of vein removed for heart bypass surgery. Researchers funded by the British Heart Foundation found that these stem cells can stimulate new blood vessels to grow, which could potentially help repair damaged heart muscle after a heart attack.

27 Apr 2010

New discovery links Slitrk5 gene to development of OCD-like behaviors

27 Apr 2010

Jefferson Medical College surgeon uses artificial liver assist device as bridge to transplantation

Cataldo Doria, M.D., Ph.D., Nicoletti Family Professor of Transplant Surgery at Jefferson Medical College of Thomas Jefferson University, and director of the Division of Transplantation at Thomas Jefferson University Hospital is the first transplant surgeon in the United States to use a new totally artificial liver assist device as a bridge to transplantation.

27 Apr 2010

Study suggests way to predict tumors most likely to respond to chemotherapy and radiation

Levels of a key type of immune cell are higher in head and neck cancer patients whose tumors are linked to the human papillomavirus, or HPV, according to researchers at the University of Michigan Comprehensive Cancer Center.

27 Apr 2010

SAFC to invest $6.25M for creating 'Center of Excellence' for dry powder media manufacturing

SAFC®, a member of the Sigma-Aldrich® Group, today announced a $6.25 million investment program to expand its Lenexa, KS, facility and create a global 'Center of Excellence' for the seamless upstream and downstream production of dry powder media and reagents. The investment, part of SAFC's worldwide facilities initiative, is designed to better serve the biopharmaceutical industry by creating 'Centers of Excellence' for manufacturing and supply chain optimization.

27 Apr 2010

Scientists develop rapid point-of-care diagnostic test to measure CD4 T-cells

Scientists at Australia's Burnet Institute have developed a rapid point-of-care diagnostic test for the measurement of CD4 T-cells, a marker of the immune system for people living with HIV and AIDS.

27 Apr 2010