Cell Biology News and Research

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Co-operation between GSF and clinic improves outlook for sarcoma patients

Hyperthermia, combined with chemotherapy, improves the chances of healing and survival of patients with low-lying, soft tissue sarcomas. At the Annual General Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, the GSF scientist Prof. Dr Rolf D.

16 Jul 2007

Master switch for the production of brown fat discovered

Researchers at Dana-Farber Cancer Institute have identified a long-sought "master switch" in mice for the production of brown fat, a type of adipose tissue that generates heat and counters obesity caused by overeating.

11 Jul 2007

New ulcerative colitis gene found

Researchers at The Hospital for Sick Children (SickKids), Mount Sinai Hospital and the University of Pittsburgh have identified a previously unsuspected gene found to be associated with ulcerative colitis.

9 Jul 2007

Support for chromosomal theory of cancer found in cancers' development of drug resistance

Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance.

28 Jun 2007

New type of mouse embryonic stem cell discovered

Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem (ES) cells, the National Institutes of Health (NIH) have announced.

28 Jun 2007

Polymeric nanoparticles show potential as new method for drug delivery

Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles.

28 Jun 2007

Scientists discover a new line of communication between nervous system cells

In a host of neurological diseases, including multiple sclerosis (MS) and several neuropathies, the protective covering surrounding the nerves - an insulating material called myelin - is damaged.

27 Jun 2007

New insight into the mechanism by which glial cells recognize and myelinate axons

In a host of neurological diseases, including multiple sclerosis (MS) and several neuropathies, the protective covering surrounding the nerves - an insulating material called myelin - is damaged.

27 Jun 2007

Call for global push to advance research in synthetic biology

With research backgrounds ranging from materials engineering to molecular biophysics, seventeen leading scientists issued a statement announcing that, much as the discovery of DNA and creation of the transistor revolutionized science, there is a new scientific field on the brink of revolutionizing our approach to problems ranging from eco-safe energy to outbreaks of malaria.

26 Jun 2007

DNA repair by Brca2 prevents medulloblastoma

St. Jude investigators have gained some of the first major insights into how certain genes known to prevent cancer also guide the nervous system's normal development before birth and during infancy by repairing DNA damage.

23 Jun 2007

DNA repair proteins monitored at double-strand break

St. Jude investigators recently had a molecule's eye view of the human cell's DNA repair kit as it assembled on a double-strand break to link together the broken ends.

23 Jun 2007

New target for therapies for retinopathy

A protein long thought to be one of the body's supporting players has quietly been taking a lead role in healthy eyesight, a discovery that could rapidly lead to treatments for babies born before their eyes are finished growing, University of Florida and Harvard Medical School researchers have found.

19 Jun 2007

Alzheimer's-associated enzyme beta-secretase can disrupt neural activity in the brain

An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures.

19 Jun 2007

Wurst protein plays a decisive role in breathing

A newly discovered transmembrane protein called "Wurst" (sausage) appears to play a decisive role in breathing ? possibly in all animals, from flies to human beings.

18 Jun 2007

Scientists decode RNA mystery

A team of University of Maryland scientists have made a discovery that will help better direct drug therapies to their molecular targets.

15 Jun 2007

Researchers shed light on shrinking of chromosomes

A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes.

15 Jun 2007

Researchers find new mechanism of action of the anti-cancer drug sorafenib

Virginia Commonwealth University Massey Cancer Center researchers have uncovered a new mechanism of action of the anti-cancer drug sorafenib, which could stimulate the development of novel regimens in which it is combined with other molecularly targeted agents for patients with blood cancers and solid tumors.

15 Jun 2007

Researchers reprogram normal tissue cells into embryonic stem cells

Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.

8 Jun 2007

Researchers turn normal tissue cells into embryonic stem cells

8 Jun 2007

HIV uses pathways to infect cells

Like hobos on a train, HIV, the virus that causes AIDS, uses a pre-existing transport system to leave one infected cell and infect new ones, Hopkins scientists have discovered.

8 Jun 2007