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Researchers watch repair proteins arrive around DNA breaks

Investigators at St. Jude Children's Research Hospital had a molecule's eye view of the human cell's DNA repair kit as it assembled on a double-strand break to link together the broken ends.

10 May 2007

Study implicates protein as a trigger of advanced prostate cancer recurrence

Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.

9 May 2007

Sperm from diabetic men have greater levels of DNA damage which may affect their fertility

In the first study to compare the quality of DNA in sperm from diabetic and non-diabetic men, researchers at Queen’s University Belfast showed that the DNA in the nuclei of the sperm cells had greater levels of fragmentation in diabetic men, and that there were more deletions of DNA in the tiny, energy-generating structures in the cells called mitochondria.

8 May 2007

Little-known cell networks vital to circadian rhythm

Circadian rhythm is the basic 24-hour cycle that involves various behaviors, including sleeping and eating, in all living organisms.

4 May 2007

There may be a real code to chromosomal organization

The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms , including humans , buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes, said the Baylor College of Medicine senior author of a report that appears online in the Public Library of Science Genetics, an open-access publication.

4 May 2007

New hope for patients with premature aging condition progeria

There is renewed hope for treatment of a rare genetic condition that causes rapidly accelerated aging and leads to an average life expectancy of 13 years.

4 May 2007

Diabetes damages DNA in men's sperm and may affect fertility

Scientists have found that sperm from diabetic men have greater levels of DNA damage than sperm from men who do not have the disease.

4 May 2007

Sleep deprivation can adversely affect a person's decision-making

Gambling is a risky activity that can potentially result in the loss of a significant amount of money.

2 May 2007

Why do some people get fat even when they eat relatively little?

What creates that irresistible urge for a bag of potato chips or a hunk of chocolate cake, as opposed to a nice crisp apple? Can food urges be irresistible?

2 May 2007

Estrogen fluctuation affects epileptic seizures

In more than a third of women with epilepsy, seizures fluctuate across the menstrual cycle, due in part to continually fluctuating effects of estrogen on the neural circuitry in the hippocampus, a region of the brain involved in learning and memory - and in epileptic seizures.

1 May 2007

Identifying cardiorespiratory neurocircuitry involved in central command during exercise in humans

For almost one hundred years the brain's ,central command, system , whose charge includes controlling the body's cardiorespiratory response to exercise , has been pursued. Animal experiments and functional imaging studies have provided clues to the location of this system, but the underlying electrophysiological activity has never been measured.

30 Apr 2007

Food-associated cues linked to obesity

A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published in BMC Biology suggests.

27 Apr 2007

Scientists discover important step in cortisol production

When a person's under stress or injured, the adrenal gland releases cortisol to help restore the body's functions to normal.

25 Apr 2007

Novel forms of synaptic plasticity uncovered

The Chicago Medical School (CMS) of the Rosalind Franklin University of Medicine and Science (RFUMS) have announced that Assistant Professor of Cell Biology and Anatomy, Athanasios Tzounopoulos, has uncovered novel forms of synaptic plasticity that occur at the very first step in the processing of sound in the central nervous system. His findings are released in Neuron.

20 Apr 2007