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Study finds some insulin production in almost half of diabetes patients

Some insulin is still produced in almost half of the patients that have had type 1 diabetes for more than ten years.

22 Jun 2017

Researchers use 3D printing-inspired process to create new blood vessels in teeth

While root canals are effective in saving a tooth that has become infected or decayed, this age-old procedure may cause teeth to become brittle and susceptible to fracture over time. Now researchers at OHSU in Portland, Oregon, have developed a process by which they can engineer new blood vessels in teeth, creating better long-term outcomes for patients and clinicians.

12 Jun 2017

Anti-heroin vaccine developed at TSRI proven effective in primate models

A vaccine developed at The Scripps Research Institute (TSRI) to block the "high" of heroin has proven effective in non-human primates. This is the first vaccine against an opioid to pass this stage of preclinical testing.

6 Jun 2017

Newly discovered mechanism in type 2 diabetes opens doors to clinical treatments

A newly discovered mechanism behind reduced insulin production in type 2 diabetes is now being presented.

6 Jun 2017

Novel vaccine therapy can generate immune responses in patients with HPV-related head and neck cancer

A novel vaccine therapy can generate immune responses in patients with head and neck squamous cell carcinoma (HNSCCa), according to researchers at the Abramson Cancer Center of the University of Pennsylvania.

31 May 2017

Researchers show how DPF2 protein controls blood cell production in leukemia

Many things go wrong in cells during the development of cancer. At the heart of the chaos are often genetic switches that control the production of new cells.

23 May 2017

Rat study reveals new treatment approach that could potentially prevent osteoarthritis

Maintaining the supply of a molecule that helps to nourish cartilage prevented osteoarthritis in animal models of the disease, according to a report published in Nature Communications online May 11.

11 May 2017

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

10 May 2017

UT Southwestern study sheds light on role of hormone ghrelin in blood glucose control

UT Southwestern research investigating the blood glucose-regulatory actions of the hormone ghrelin may have implications for development of new treatments for diabetes.

10 May 2017

Study findings could help identify treatments for balding and hair graying

Researchers at the UT Southwestern Medical Center have discovered the cells that are directly responsible for hair growth and the mechanism that causes gray hair. The study results could help in identifying feasible treatments for balding and hair graying.

9 May 2017

UT Southwestern researchers uncover mechanism linked to balding and hair graying

UT Southwestern Medical Center researchers have identified the cells that directly give rise to hair as well as the mechanism that causes hair to turn gray - findings that could one day help identify possible treatments for balding and hair graying.

9 May 2017

Novel approach cures diabetes in mice for one year without side effects

A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots.

5 May 2017

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Medical University of South Carolina investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not compromise Th17 cells' effectiveness against large tumors, in the March 9, 2017 issue of JCI Insight.

17 Apr 2017

Scientists discover potential trigger for MDS in children with rare genetic disorder

Myelodysplastic syndrome is an umbrella term used to describe disorders characterized by the bone marrow's inability to produce normal blood cells.

12 Apr 2017

Scientists discover how insulin-producing cells show differences in age

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

12 Apr 2017

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Researchers at the University of Helsinki, Finland, have uncovered a mechanism through which a mutation in the STAT3 gene leads to a disorder in the development of the pancreas and to infant diabetes.

11 Apr 2017

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Like private investigators on a stake out, St. Jude Children's Research Hospital scientists used patience and video surveillance-like tools to identify cells that trigger blood cell development.

10 Apr 2017

Researchers identify molecular switch that converts skin cells into blood vessel cells

Researchers from the University of Illinois at Chicago have identified a molecular switch that converts skin cells into cells that make up blood vessels, which could ultimately be used to repair damaged vessels in patients with heart disease or to engineer new vasculature in the lab.

7 Apr 2017

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

5 Apr 2017

New microfluidic technique may provide patients with less painful test for multiple myeloma

Multiple myeloma is a cancer of the plasma cells, which are white blood cells produced in bone marrow that churn out antibodies to help fight infection. When plasma cells become cancerous, they produce abnormal proteins, and the cells can build up in bone marrow, ultimately seeping into the bloodstream.

4 Apr 2017