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New technologies and recent advances in the study of T cells and T-cell epitope discovery in food allergy research

In a recent study, scientists reviewed the latest technological advancements and T cell epitope discovery associated with food allergy.

28 Nov 2022

How gut microbes influence immune response to SARS-CoV-2

An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Nov 2022

Researchers make first bone marrow 'organoids' to capture key features of human bone marrow

Scientists from Oxford University and the University of Birmingham have made the first bone marrow 'organoids' that capture the key features of human bone marrow.

15 Nov 2022

TYK2 inhibitor identifies as a promising drug candidate for preventing type 1 diabetes

According to a study, type 1 diabetes could be prevented by inhibiting a gene associated with the onset of the disease.

10 Nov 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes-;or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults.

12 Oct 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

17 Aug 2022

Elevated acetate levels reprogram gut microbiota during alcohol intake

Chronic alcohol use is a major cause of liver damage and death: Approximately 30,000 persons in the United States die annually from alcoholic liver diseases, such as cirrhosis.

11 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

The characteristics of circulating T follicular helper cells in COVID-19 patients across mild to severe disease

Researchers found that late generation of functional SARS-CoV-2-selective circulating T follicular helper cells correlated with severe illness.

18 Jul 2022

Kyoto scientists reveal characteristic behaviors of erythropoietin-producing cells

A research team at Kyoto University has revealed characteristic behaviors of erythropoietin (Epo)-producing cells.

30 Jun 2022

New study uncovers the impact of genetic mutations on lifelong blood cell production

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life.

1 Jun 2022

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets.

25 May 2022

New study helps explain the immune system’s response to skin infections and skin cancers

It is well established that older adults are more susceptible to infection and their immune systems less capable of generating a strong immune response.

4 May 2022

New insights into SARS-CoV-2 immunity gained from natural infection

Antibody-secreting cells (ASCs) peaked at 3-4 weeks and were still being produced at 3-4 months in patients hospitalized with COVID-19, according to a study published in the peer-reviewed journal Viral Immunology.

25 Mar 2022

Discovery may open novel avenues to prevent or treat hematological malignancies

Scientists at Yale Cancer Center have discovered new consequences of specific gene mutations that play a role in the development of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).

17 Mar 2022

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19.

15 Feb 2022