Cellular Biology News and Research

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Novel therapies to prevent metastasis

In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor.

8 May 2007

Diabetes drug rosiglitazone boosts power of platinum chemotherapy

A widely used diabetes drug dramatically boosted the potency of platinum-based cancer drugs when administered together to a variety of cancer cell lines and to mice with tumors, scientists from Dana-Farber Cancer Institute report.

8 May 2007

Master regulator for epithelial tissue regeneration found

The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes.

4 May 2007

Scientists work out mechanism underlying asymmetric cell division in nematode worms

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells.

4 May 2007

Single gene is responsible for most cool temperature sensation

The discovery, reported in the May 3 issue of the journal Neuron, might one day lead to the development of drugs that induce cold sensation as an analgesic, or block it to prevent certain forms of chronic pain associated with cold sensation.

4 May 2007

New hope for patients with premature aging condition progeria

There is renewed hope for treatment of a rare genetic condition that causes rapidly accelerated aging and leads to an average life expectancy of 13 years.

4 May 2007

Ultra fast and ultra active: the strange life of the extraocular muscles

The eye, often called the window to the soul, may become a window to the mysteries of muscular dystrophy, a debilitating muscle disease that often leads to death in early adulthood.

2 May 2007

Genetic differences may explain why many Asian women who never smoked develop lung cancer

Analysis of three genetic mechanisms that cause non-small cell lung cancer might explain why East Asians respond better than other ethnic groups to a certain type of chemotherapy, a team led by UT Southwestern Medical Center researchers has found.

27 Apr 2007

Mutations in a gene that helps regulate cell division linked to inherited form of fatal lung disease

Mutations in a gene that helps regulate cell division are responsible for some inherited cases of a fatal lung disease, researchers at UT Southwestern Medical Center have found.

27 Apr 2007

Scientists develop method to convert normal human blood cells into

Cancer researchers led by Dr. John Dick at Ontario Cancer Institute (OCI) have developed a method to convert normal human blood cells into "human" leukemia stem cells.

27 Apr 2007

Stem cell identity in culture may strongly depend on the cellular microenvironment

Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.

26 Apr 2007

Researchers identify key function of a molecule - wound healing in the skin

The skin is the largest organ of the human body. It protects against environmental influences and pathogens, regulates body temperature, and protects the body against dehydration.

24 Apr 2007

UNC-45 protein critical to proper formation of muscles

Proper formation of the proteins that power heart and skeletal muscle seems to rely on a precise concentration of a "chaperone" protein known as UNC-45, according to a new study.

24 Apr 2007

Novel forms of synaptic plasticity uncovered

The Chicago Medical School (CMS) of the Rosalind Franklin University of Medicine and Science (RFUMS) have announced that Assistant Professor of Cell Biology and Anatomy, Athanasios Tzounopoulos, has uncovered novel forms of synaptic plasticity that occur at the very first step in the processing of sound in the central nervous system. His findings are released in Neuron.

20 Apr 2007

Scent prediction test

The scent of lily of the valley hangs in the air for readers of the journal Angewandte Chemie: just rub the journal's cover and enjoy a lily-of-the-valley scent.

19 Apr 2007

Jefferson participates in global study to extend effectiveness of drug for Parkinson's

After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that controls muscle movement by replacing lost dopamine, they begin to experience motor complications that include a shortened response to each dose of L-dopa.

19 Apr 2007

Single master gene crucial for nerve cell insulation

Researchers funded by the National Institutes of Health have discovered how a defect in a single master gene disrupts the process by which several genes interact to create myelin, a fatty coating that covers nerve cells and increases the speed and reliability of their electrical signals.

17 Apr 2007

Astrocytes may contribute to Lou Gehrig's disease

Two papers by Columbia and Harvard researchers report for the first time that astrocytes (the most abundant non-neuronal cells in the central nervous system), which carry a mutated gene known to cause some cases of amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease), induce motor neuron death.

16 Apr 2007

Massive gene screening points way to more effective chemotherapy

Using a technology that can quickly screen all 20,000-plus human genes for biological activity, scientists have isolated 87 genes that seem to affect how sensitive human cancer cells are to certain chemotherapy drugs.

12 Apr 2007

Female stem cells work better

Female stem cells derived from muscle have a greater ability to regenerate skeletal muscle tissue than male cells, according to a study at Children's Hospital of Pittsburgh of UPMC.

10 Apr 2007