Central Nervous System News and Research

RSS

Sex differences in depression: Including transgender and intersex populations in mental health research

In 2016, recognizing that lack of research in female animals was hampering the success of treatments for mood disorders, the National Institutes of Health (NIH) changed its policy for basic research to include sex as a biological variable for basic research, a move that triggered an explosion of research into sex differences.

1 Aug 2023

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

A group of researchers investigated the neurotropic potential of SARS-CoV-2 and its variants by studying their ability to invade the brain through the olfactory pathway in hamsters.

1 Aug 2023

RSV vaccines for older adults: 2023 ACIP recommendations

A recent report published in Morbidity and Mortality Weekly Report provided clinical guidance on Respiratory syncytial virus (RSV) vaccines for adults ≥60 years.

1 Aug 2023

Novel tool uncovers new cell types in the visual system of flies

New York University researchers have discovered new cell types in the visual system of flies, made possible by their creation of a tool that finds and labels neurons during development.

31 Jul 2023

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

Researchers investigated the safety and pharmacokinetics of JNJ-54175446 in a double-blind, multicenter, randomized controlled trial (RCT).

31 Jul 2023

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

A novel vaccine that targets inflamed brain cells associated with Alzheimer's disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023.

31 Jul 2023

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

In a recent study, researchers designed substituted spiro indolin-1,2-diazepine derivatives '5a–v' with cholinesterase inhibitory activities as anti-Alzheimer's disease agents.

31 Jul 2023

Scientists map 3D structure of kappa opioid receptor

Opioids remain the most potent and effective pain relievers in medicine, but they're also among the most addictive drugs that can halt a person's ability to breathe during an overdose -; which can be deadly.

27 Jul 2023

Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome

Researchers utilize bibliometric analysis to investigate the relationship between the gut microbiome and Alzheimer's disease pathogenesis.

25 Jul 2023

The effect of dietary supplements on antibody levels in pregnant women vaccinated with inactivated SARS-CoV-2 vaccine

Researchers discuss the effects of supplements on antibody levels following immunization against SARS-CoV-2 with inactivated vaccines.

21 Jul 2023

Study explores the effectiveness of caffeine consumption for headaches: trigger or remedy?

Caffeine has a dual role in headaches as it can induces or remediate them.

20 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

Fentanyl overdose reversal: New hope on the horizon

According to the Centers for Disease Control, 100,000 Americans die each year from an overdose, most due to the use of synthetic opiates like fentanyl. While naloxone, currently the only an antidote for opiate overdose, has become more common, it is less effective against fentanyl-class synthetic opioids.

18 Jul 2023

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Francesca Marassi, PhD, professor and chair of biophysics at the Medical College of Wisconsin (MCW), has been awarded a five-year, $13 million program project grant (PPG) by the National Institutes of Health (NIH) to study misplaced calcification in the eyes and brains of patients suffering from age-related macular degeneration (AMD) and Alzheimer's disease (AD).

18 Jul 2023

Study highlights the potential of cell replacement therapy for Huntington's disease

New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.

17 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

A team led by researchers at the Mechanisms of Inherited Kidney Disorders (MIKADO) group at the University of Zurich (Zurich, Switzerland) has used Insilico Medicine's generative artificial intelligence (AI) target discovery engine, PandaOmics, to identify actionable drug targets for the lysosomal storage disease cystinosis and to validate them in preclinical models of the disease.

14 Jul 2023

Central Nervous System News and Research

Sex differences in depression: Including transgender and intersex populations in mental health research

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

RSV vaccines for older adults: 2023 ACIP recommendations

Novel tool uncovers new cell types in the visual system of flies

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

Scientists map 3D structure of kappa opioid receptor

Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome

The effect of dietary supplements on antibody levels in pregnant women vaccinated with inactivated SARS-CoV-2 vaccine

Study explores the effectiveness of caffeine consumption for headaches: trigger or remedy?

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Fentanyl overdose reversal: New hope on the horizon

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Study highlights the potential of cell replacement therapy for Huntington's disease

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

New study reveals mast cells' surprising role in allergy-related avoidance behavior

Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

New precision medicine trial shows promise for treating rare brain tumors

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News