Central Nervous System News and Research

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Nektar presents NKTR-181 preclinical data at ASA 2010 Annual Meeting

Nektar Therapeutics today presented new preclinical data demonstrating that NKTR-181, a mu-opioid analgesic with a novel molecular structure, dramatically reduces abuse liability while providing analgesia comparable to oxycodone and morphine.

18 Oct 2010

Neuroprotective properties of laquinimod for RRMS presented at 26th ECTRIMS Congress

Teva Pharmaceutical Industries Ltd. and Active Biotech announced today that data providing further evidence of the neuroprotective properties of laquinimod in animal studies were presented at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Gothenburg, Sweden.

15 Oct 2010

Questcor, CNF partner to fund infantile spasms research

Questcor Pharmaceuticals, Inc. announced that it is partnering with the Child Neurology Foundation (CNF) to fund a $30,000 grant to support research into infantile spasms (IS). Catherine Chu-Shore, MD, of Massachusetts General Hospital was selected by CNF as the recipient of this first-ever "Logan Infantile Spasms Research Award."

15 Oct 2010

Galenea awarded $4.5M NIMH grant to advance Multiwell, Automated NeuroTRansmission Assay platform

Galenea Corp. has been awarded a highly competitive grant from the National Institute of Mental Health in response to the solicitation "Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)," funded by the American Recovery and Reinvestment Act of 2009. Galenea has developed an innovative technology platform, termed MANTRA™ (Multiwell, Automated NeuroTRansmission Assay) that enables high-throughput screening for the identification of small molecule modulators of synaptic transmission.

14 Oct 2010

Genmab and Lundbeck enter agreement to develop antibody therapeutics

Genmab A/S announced today an agreement to create and develop human antibody therapeutics for disorders of the central nervous system (CNS) with H. Lundbeck A/S. Genmab will create novel human antibodies to three targets identified by Lundbeck. Lundbeck will have access to Genmab's antibody creation and development capabilities, including its state of the art, fully automated pre-clinical antibody screening and characterization capabilities and its proprietary stabilized IgG4 and UniBody therapeutic antibody platforms.

13 Oct 2010

Lundbeck, Merck announce commercialization agreement for SYCREST sublingual tablets

H. Lundbeck A/S (Lundbeck) and Merck, known outside the United States and Canada as MSD, today announced a commercialization agreement for SYCREST (asenapine) sublingual tablets (5 mg, 10 mg). Under the terms of the agreement, Lundbeck will pay an undisclosed fee as well as product supply payments in exchange for exclusive commercial rights to SYCREST in all markets outside the United States, China and Japan. Lundbeck expects to launch SYCREST in the European Union (EU), where it is already approved, at the beginning of 2011.

12 Oct 2010

Yoga decreases anxiety in childhood cancer patients and their parents

A new study reports that yoga can reduce the stress of cancer diagnosis and treatment experienced by childhood cancer patients and their parents. The findings were published in the September/October 2010 edition of Journal of Pediatric Oncology Nursing, published by the Association of Pediatric Hematology/Oncology Nurses (APHON).

11 Oct 2010

Takeda, Envoy enter three-year research alliance to develop schizophrenia drug

Takeda Pharmaceutical Company Limited, a global pharmaceutical company, and Envoy Therapeutics Inc., a recently formed drug discovery company, today announced that they have formed a three-year research alliance aimed at discovering drugs for schizophrenia that will have greater efficacy and safety compared to current therapies.

11 Oct 2010

GeneGo integrates SDM platform with MetaCore and MetaDrug

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that they have integrated GenomeQuest's Sequence Data Management (SDM) platform with GeneGo's MetaCore and MetaDrug.

8 Oct 2010

Study suggests athletes suffer a form of injury that is difficult to diagnose

A study by researchers at Purdue University suggests that some high school football players suffer undiagnosed changes in brain function and continue playing even though they are impaired.

8 Oct 2010

StemCells provides update on PMD Phase I clinical trial

StemCells, Inc. today provided an update on its ongoing Phase I clinical trial in Pelizaeus-Merzbacher Disease (PMD), a fatal myelination disorder that afflicts male children.

8 Oct 2010

Microglial inflammation promotes MAPT pathologies

Cells that help to protect the central nervous system may also contribute to pathological changes in the brain. New research, published by Cell Press in the October 7th issue of the journal Neuron, provides mechanistic insight into a link between the immune system and neurodegenerative disorders like Alzheimer's disease that are associated with abnormal accumulation of tau protein.

7 Oct 2010

NeuroDerm receives $1M grant for development of ND0611 dermal patch for Parkinson's disease

NeuroDerm, Ltd. was informed today that it was awarded a grant of $1M by The Michael J. Fox Foundation for Parkinson's Research. These funds will support the next clinical study with ND0611, a new dermal patch for the treatment of Parkinson's disease, as part of the Foundation's prestigious Clinical Intervention Awards 2010 program. This study will evaluate the safety, tolerability, levodopa pharmacokinetics, and possible clinical benefits of ND0611 in advanced Parkinson's disease patients.

6 Oct 2010

Medtronic launches new KYPHON Express Curette for scraping or scoring bone in the spine

Medtronic Inc. today announced the launch of the new KYPHON® Express™ Curette for scraping or scoring bone in the spine, including during treatment of vertebral compression fractures with minimally invasive KYPHON® Balloon Kyphoplasty.

6 Oct 2010

Galapagos honored with 2010 EUROPEAN BIOTECHNICA AWARD

The Belgian biotech company Galapagos has won the 2010 EUROPEAN BIOTECHNICA AWARD. Galapagos thus secures the lion's share of the prize money totalling 75,000 euros, which is offered every year in the competition staged by Deutsche Messe AG and its partners. The award celebrates innovative European companies from the biotechnology sector and the life sciences.

5 Oct 2010

McGill University joins two leading Swiss research institutions to enhance neuroscience research

Building on its worldwide reputation as a leader in neuroscience research, McGill University today joined with two leading Swiss research institutions - the University of Zurich (UZH) and the Swiss Federal Institute of Technology (ETHZ) - to enhance neuroscience research in a host of areas, in fields that include pain therapy, Alzheimer's disease, synapse modelling and repair, neuroimmunology and genetic mechanisms of brain diseases.

5 Oct 2010

UofL School of Nursing awarded $792,000 grant to develop nursing informatics education

The University of Louisville School of Nursing has earned a $792,000 grant from the U.S. Department of Health and Human Services Health Resources and Services Administration to develop nursing informatics education for UofL's undergraduate and graduate nursing students as well as practicing nurses from University of Louisville Hospital.

4 Oct 2010

Vibrant joins Bike MS NYC to raise money for National Multiple Sclerosis Society

Vibrant will participate in Bike MS NYC on Sunday, October 3 to increase awareness of Multiple Sclerosis and to raise money for the National Multiple Sclerosis Society. The race, hosted by the Southern NY Chapter of the National Multiple Sclerosis Society, will include nearly 6,000 cyclists across two Bike MS NYC locations.

1 Oct 2010

American Brain Tumor Association awards $100,000 clinical research grant

The Section on Tumors of the American Association of Neurological Surgeons and Congress of Neurological Surgeons has announced a $100,000 two-year ($50,000/year) clinical research grant funded by the American Brain Tumor Association (ABTA). The application is open exclusively to neurosurgeons who are members of the AANS/CNS Section on Tumors.

30 Sep 2010

Researchers receive NIH award to investigate regenerative potential of retinal cells

Zhang and co-principal investigators Sheng Ding, PhD, from The Scripps Research Institute, and Thomas Reh, PhD from the University of Washington, received the highest possible scores for their proposal to investigate the regenerative potential of retinal cells. Their long-term goal is to restore visual function lost through diseases such as macular degeneration and retinitis pigmentosa.

30 Sep 2010

Central Nervous System News and Research

Nektar presents NKTR-181 preclinical data at ASA 2010 Annual Meeting

Neuroprotective properties of laquinimod for RRMS presented at 26th ECTRIMS Congress

Questcor, CNF partner to fund infantile spasms research

Galenea awarded $4.5M NIMH grant to advance Multiwell, Automated NeuroTRansmission Assay platform

Genmab and Lundbeck enter agreement to develop antibody therapeutics

Lundbeck, Merck announce commercialization agreement for SYCREST sublingual tablets

Yoga decreases anxiety in childhood cancer patients and their parents

Takeda, Envoy enter three-year research alliance to develop schizophrenia drug

GeneGo integrates SDM platform with MetaCore and MetaDrug

Study suggests athletes suffer a form of injury that is difficult to diagnose

StemCells provides update on PMD Phase I clinical trial

Microglial inflammation promotes MAPT pathologies

NeuroDerm receives $1M grant for development of ND0611 dermal patch for Parkinson's disease

Medtronic launches new KYPHON Express Curette for scraping or scoring bone in the spine

Galapagos honored with 2010 EUROPEAN BIOTECHNICA AWARD

McGill University joins two leading Swiss research institutions to enhance neuroscience research

UofL School of Nursing awarded $792,000 grant to develop nursing informatics education

Vibrant joins Bike MS NYC to raise money for National Multiple Sclerosis Society

American Brain Tumor Association awards $100,000 clinical research grant

Researchers receive NIH award to investigate regenerative potential of retinal cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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