Chagas Disease News and Research

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Chagas (pronounced SHA-gus) disease is named after the Brazilian physician Carlos Chagas, who discovered it in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors that are found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

People can become infected in various ways. In Chagas-endemic areas, the main way is through vectorborne transmission. The insect vectors are called triatomine bugs. These blood-sucking bugs get infected by biting an infected animal or person. Once infected, the bugs pass T. cruzi parasites in their feces. The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs. During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as “kissing bugs.” After they bite and ingest blood, they defecate on the person. The person can become infected if T. cruzi parasites in the bug feces enter the body through mucous membranes or breaks in the skin. The unsuspecting, sleeping person may accidentally scratch or rub the feces into the bite wound, eyes, or mouth.
VIMOVO delayed-release tablets receive FDA approval

VIMOVO delayed-release tablets receive FDA approval

Opinions: Sanitation and women, child health; GM in Global Food Security bill; U.S. malaria strategy; GHI on NTDs; Haiti recovery

Opinions: Sanitation and women, child health; GM in Global Food Security bill; U.S. malaria strategy; GHI on NTDs; Haiti recovery

Manipulating physiology of "kissing bug" may help prevent transmission of Chagas' disease

Manipulating physiology of "kissing bug" may help prevent transmission of Chagas' disease

Researchers develop new diagnostic approach to fight against Chagas disease

Researchers develop new diagnostic approach to fight against Chagas disease

Abbott's first-quarter worldwide pharmaceutical sales increases by 12.9%

Abbott's first-quarter worldwide pharmaceutical sales increases by 12.9%

Tapeworm infections of brain increasing in Mexico and bordering southwestern states

Tapeworm infections of brain increasing in Mexico and bordering southwestern states

San Diego Union-Tribune examines pharma's growing interest in neglected diseases

San Diego Union-Tribune examines pharma's growing interest in neglected diseases

Scientists identify potential new method for treating sleeping sickness

Scientists identify potential new method for treating sleeping sickness

Major breakthrough may help develop low toxicity drugs for sleeping sickness

Major breakthrough may help develop low toxicity drugs for sleeping sickness

'Dipstick' 3-in-1 test for detection of Chagas' disease, leishmaniasis and African trypanosomiasis

'Dipstick' 3-in-1 test for detection of Chagas' disease, leishmaniasis and African trypanosomiasis

Scientists determine structure of enzyme essential to the survival of protozoan parasites

Scientists determine structure of enzyme essential to the survival of protozoan parasites

Chagas disease transmission in Peru linked to migration and urbanization patterns

Chagas disease transmission in Peru linked to migration and urbanization patterns

NIH awards $14.6M for Eukaryotic Pathogen Genome Database Resource expansion

NIH awards $14.6M for Eukaryotic Pathogen Genome Database Resource expansion

Researchers describe how PDNF protein prolongs the life of T. cruzi parasite

Researchers describe how PDNF protein prolongs the life of T. cruzi parasite

Pfizer,DNDi partner to Identify NTD drugs; Sanofi-Aventis, medicines for malaria launch drug study

Pfizer,DNDi partner to Identify NTD drugs; Sanofi-Aventis, medicines for malaria launch drug study

Pfizer and DNDi to battle against HAT, VL and Chagas disease

Pfizer and DNDi to battle against HAT, VL and Chagas disease

NIH awards The Tufts CTSI and Tufts University four supplemental grants

NIH awards The Tufts CTSI and Tufts University four supplemental grants

Genzyme named to the 2009 Dow Jones Sustainability World Index

Genzyme named to the 2009 Dow Jones Sustainability World Index

Also in Global Health news: U.S. food aid declines; agriculture in Zimbabwe; U.S.-backed ITN network; reducing maternal mortality; DNDI expands; healthcare in Congo

Also in Global Health news: U.S. food aid declines; agriculture in Zimbabwe; U.S.-backed ITN network; reducing maternal mortality; DNDI expands; healthcare in Congo

Clinton Global Initiative to raise awareness and funding for NTD control and elimination

Clinton Global Initiative to raise awareness and funding for NTD control and elimination