Chagas Disease News and Research

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Chagas (pronounced SHA-gus) disease is named after the Brazilian physician Carlos Chagas, who discovered it in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors that are found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

People can become infected in various ways. In Chagas-endemic areas, the main way is through vectorborne transmission. The insect vectors are called triatomine bugs. These blood-sucking bugs get infected by biting an infected animal or person. Once infected, the bugs pass T. cruzi parasites in their feces. The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs. During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as “kissing bugs.” After they bite and ingest blood, they defecate on the person. The person can become infected if T. cruzi parasites in the bug feces enter the body through mucous membranes or breaks in the skin. The unsuspecting, sleeping person may accidentally scratch or rub the feces into the bite wound, eyes, or mouth.
Sustained engagement, partnership needed to implement new treatments for neglected diseases

Sustained engagement, partnership needed to implement new treatments for neglected diseases

New LAMP malaria test to improve diagnosis for imported UK cases

New LAMP malaria test to improve diagnosis for imported UK cases

AfriCoLeish receives grant from European Union to test new treatments for kala-azar

AfriCoLeish receives grant from European Union to test new treatments for kala-azar

Documentary film examines Chagas disease in Argentina

Documentary film examines Chagas disease in Argentina

New Japan-driven initiative to accelerate research, development innovation for neglected diseases

New Japan-driven initiative to accelerate research, development innovation for neglected diseases

Student coalition ranks research universities' spending and activities on neglected diseases, other illnesses

Student coalition ranks research universities' spending and activities on neglected diseases, other illnesses

New Pope will need to consider burden of NTDs

New Pope will need to consider burden of NTDs

DNDi receives 2013 BBVA Foundation Frontiers of Knowledge and Culture Award

DNDi receives 2013 BBVA Foundation Frontiers of Knowledge and Culture Award

DNDi in Latin America wins Carlos Slim Health Award for innovations in drug development

DNDi in Latin America wins Carlos Slim Health Award for innovations in drug development

VNI cures both acute and chronic forms of Chagas disease

VNI cures both acute and chronic forms of Chagas disease

Chagas disease costs $7B annually worldwide, according to study

Chagas disease costs $7B annually worldwide, according to study

WHO reports unprecedented progress against 17 neglected tropical diseases

WHO reports unprecedented progress against 17 neglected tropical diseases

Fatal imbalance between global disease burden and drug development

Fatal imbalance between global disease burden and drug development

Drugs for Neglected Diseases receives UNITAID grant for paediatric HIV programme

Drugs for Neglected Diseases receives UNITAID grant for paediatric HIV programme

Fexinidazole enters Phase II/III clinical study to treat sleeping sickness

Fexinidazole enters Phase II/III clinical study to treat sleeping sickness

Malaria Box helps identify three chemical series that target treatment of NTDs

Malaria Box helps identify three chemical series that target treatment of NTDs

UC Riverside entomologists reconstruct the evolutionary history of assassin bugs

UC Riverside entomologists reconstruct the evolutionary history of assassin bugs

Financial Times features special report on NTDs

Financial Times features special report on NTDs

FIOCRUZ, DNDi and Brazil collaborate on R&D for neglected diseases

FIOCRUZ, DNDi and Brazil collaborate on R&D for neglected diseases

'Greater commitment' needed to fight NTDs

'Greater commitment' needed to fight NTDs

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