Chaperones News and Research

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Researchers discover new mechanism of cancer treatment resistance

Researchers discover new mechanism of cancer treatment resistance

Researchers study how cells adapt to stressful and complex environments

Researchers study how cells adapt to stressful and complex environments

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

Study unravels how mitochondria call for help when under stress

Study unravels how mitochondria call for help when under stress

New insights into how dendritic cells arm T cells to fight disease

New insights into how dendritic cells arm T cells to fight disease

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Indirect inhibitors of cellular respiration for treatment of glioblastoma

Indirect inhibitors of cellular respiration for treatment of glioblastoma

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Repair crews may move in to help fix the oxidative damage in protein factories

Repair crews may move in to help fix the oxidative damage in protein factories

Elucidating the function of BRCA2 gene offers insight into cancer development

Elucidating the function of BRCA2 gene offers insight into cancer development

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

Specific N-glycans regulate the development and functional maturation of SARS-CoV-2 spike protein

Specific N-glycans regulate the development and functional maturation of SARS-CoV-2 spike protein

UBR7 protein acts as a histone chaperone during DNA replication, study finds

UBR7 protein acts as a histone chaperone during DNA replication, study finds

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

Research elucidates how chaperones display "selective promiscuity" for specific proteins

Research elucidates how chaperones display "selective promiscuity" for specific proteins

Research reveals components of Sinbis virus ribonucleoproteins

Research reveals components of Sinbis virus ribonucleoproteins

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

Could GRP78 be a therapeutic target against COVID-19?

Could GRP78 be a therapeutic target against COVID-19?