Chemokines News and Research

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Why the bird flu virus H5N1 is so deadly to humans

A study published today in the open access journal Respiratory Research reveals that, in human cells, the virus can trigger levels of inflammatory proteins more than 10 times higher than the common human flu virus H1N1.

14 Nov 2005

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center. They say their findings may point to ways to effectively treat these diseases - if not stop them before they start.

4 Oct 2005

Ischemic brain injury - another promising avenue for stem cell therapy

Adult stem cell therapy quickly and significantly improves recovery of motor function in an animal model for the ischemic brain injury that occurs in about 10 percent of babies with cerebral palsy, researchers report.

4 Oct 2005

New understanding of cell movement may yield ways to brake cancer's spread

From birth until death, our cells migrate: nerve cells make their vital connections, embryonic cells move to the proper places to form organs, immune cells zero in to destroy pathogenic organisms, and cancer cells metastasize, spreading deadly disease through the body. Scientists studying these migrations didn't know how cells determined where to go. Until now.

1 Aug 2005

Scientists have begun to clarify how one of the body's molecules controls the trafficking of T cells through the blood

...lymph nodes and on to tissues to fight infection -- a crucial response that sometimes goes awry, attacking the body's own tissues and causing autoimmune diseases.

17 Jul 2005

White blood cell called a neutrophil appears to be crucial to abdominal aortic aneurysm formation

Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at any time. About 20,000 die suddenly from such a rupture. And another 36,000 have surgery to repair or replace the swelling section of aorta before time runs out.

13 Jul 2005

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).

27 Jun 2005

Chemokine Therapeutics granted new U.S patent

Chemokine Therapeutics has announced that it has been granted U.S. Patent No. 6,875,738 relating to the use of its anti-cancer compound, CTCE-9908, in the treatment of cancer and inhibition of angiogenesis. CTCE-9908 is designed to block CXCR4, a receptor found on the surface of cancer cells.

14 Jun 2005

Gene mutation protecting against malaria linked to prostate cancer incidence in African-American men

Research from the University of Cincinnati College of Medicine suggests that the 60 percent greater incidence of prostate cancer among African-American men is related to a gene mutation developed generations ago in West Africa as nature's way of providing protection from the malaria infection endemic in that part of the world.

4 Apr 2005

Brain inflammation is a sign of autism

A new study by scientists at Johns Hopkins shows that brain inflammation is a sign of autism. The findings are reported in the online edition of Annals of Neurology, the scientific journal of the American Neurological Association.

15 Nov 2004

Stem cell research may one day help cerebral palsy

Natural chemicals that assist healing may one day help transplanted adult stem cells integrate into an injured brain, helping children with cerebral palsy recover lost function, according to researchers at the Medical College of Georgia.

18 Aug 2004

Red wine is much better for you than gin

Red wine contains many complex compounds including polyphenols, which are absent from gin. They found that drinking red wine had a much greater effect in lowering levels in the bloodstream of so-called “anti-inflammatory” substances that are risk factors in the development of heart disease and stroke.

12 Aug 2004

Chemotherapy aimed at both cancer cells and their genetically normal cellular 'microenvironment' might improve the success of breast cancer treatment

In the first comprehensive survey of gene activity in each cell type composing normal and malignant breast tissue, scientists at Dana-Farber Cancer Institute have identified genes in non-cancerous supporting cells that can spur the growth of breast cancer cells.

20 Jul 2004

Harmless virus known as GBV-C slows the progression of HIV

Iowa City Veterans Affairs (VA) Medical Center and University of Iowa (UI) researchers have unlocked part of the mystery of how a harmless virus known as GBV-C slows the progression of HIV and prolongs survival for many patients.

17 Jun 2004

Jefferson scientists learn how HIV causes dementia

Ever since the AIDS epidemic began more than two decades ago, scientists have been trying to understand why as many as one-quarter of those infected with HIV develop dementia.

19 Apr 2004

New Research Information on Tumor Necrosis Therapy

Researchers for Peregrine Pharmaceuticals presented today at the Strategic Research Institute’s Clinical-Stage Product Partnering Summit in La Jolla, CA a summary of clinical experience with Tumor Necrosis Therapy (TNT). The TNT technology is being developed in the U.S. and Europe by Peregrine under the trade name Cotara™. Over 200 patients have been treated with TNT world-wide and a TNT product has been approved to treat grade III or IV advanced lung cancer in the People’s Republic of China. A Cotara registration study for brain cancer has been approved by the U.S. Food and Drug Administration, and a Phase I colorectal cancer study is on-going at Stanford University Medical Center.

25 Mar 2004