Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

CRESTOR found to reduced CV risk in patients achieving low LDL-C and hsCRP targets in new Jupiter analysis

Results from a new sub-analysis of the JUPITER study show that patients who attained a dual treatment target of LDL-C <70mg/dL and high-sensitivity C-reactive protein (hsCRP) <2mg/L with CRESTOR (rosuvastatin) 20mg achieved a greater reduction in cardiovascular events compared to placebo than those who did not (65% vs 36%, p=0.033) among men and women with low to normal cholesterol levels and elevated hsCRP.

29 Mar 2009

CRESTOR (rosuvastatin) shown to significantly reduce risk of venous thromboembolism

A new analysis from the JUPITER study shows that CRESTOR (rosuvastatin) 20mg significantly cut the risk of venous thromboembolism (VTE) by 43% (p=0.007) compared to placebo among men and women with low to normal cholesterol levels and elevated high-sensitivity C-reactive protein (hsCRP).

29 Mar 2009

Clinical effectiveness of coronary stents in the elderly

Heart disease patients 65 and older who receive stents coated with medicine to prevent blockages are more likely to survive and less likely to suffer a heart attack than people fitted with stents not coated with medication, according to a new study supported by HHS' Agency for Healthcare Research and Quality and the American College of Cardiology's National Cardiovascular Data Registry.

29 Mar 2009

Researcher links cholesterol crystals to cardiovascular attacks

For the first time ever, a Michigan State University researcher has shown cholesterol crystals can disrupt plaque in a patient's cardiovascular system, causing a heart attack or stroke.

29 Mar 2009

Simple, noninvasive finger sensor test predicts major cardiac events

Results of a Mayo Clinic study show that a simple, noninvasive finger sensor test is "highly predictive" of a major cardiac event, such as a heart attack or stroke, for people who are considered at low or moderate risk, according to researchers.

26 Mar 2009

Diabetic retinopathy more prevalent in South Asians and occurs earlier

South Asians with type 2 diabetes are significantly more at risk of losing their eyesight and losing it at an earlier age, compared to White Europeans with the same condition.

24 Mar 2009

Fit women much less likely to die from breast cancer

Physically fit women are less likely to die from breast cancer, according to a study by researchers at the University of South Carolina Arnold School of Public Health.

24 Mar 2009

Diabetics on high-fiber diets might need extra calcium

The amount of calcium your body absorbs might depend, in part, on the amount of dietary fiber you consume.

24 Mar 2009

Diabetics on high-fiber diets might need extra calcium

The amount of calcium your body absorbs might depend, in part, on the amount of dietary fiber you consume.

24 Mar 2009

Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment

Metabolites are molecular fingerprints of what your cells are up to and Dr. Arun Sreekumar wants to know the impression made by cancer.

23 Mar 2009

Environmental cardiology - the relationship between air pollution and heart disease

We are used to thinking of heart disease as a product of genetic factors or lifestyle choices, such as what we eat and how much we exercise.

23 Mar 2009

High triglyceride levels common, often untreated among Americans

High concentrations of blood fats known as triglycerides are common in the United States, according to a report in the March 23 issue of Archives of Internal Medicine.

23 Mar 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Red and processed meat linked to greater risk of death from all causes

Individuals who eat more red meat and processed meat appear to have a modestly increased risk of death from all causes and also from cancer or heart disease over a 10-year period, according to a report in the March 23 issue of Archives of Internal Medicine.

23 Mar 2009

Combination of very low LDL and normal systolic blood pressure attenuate coronary artery disease

New data published in the March 31, 2009, issue of the Journal of the American College of Cardiology show that patients with coronary artery disease (CAD) who achieve very low levels of low-density lipoprotein (LDL) cholesterol along with normal systolic blood pressure have the slowest progression of CAD.

23 Mar 2009