Chromosome 10 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 10, one copy inherited from each parent, form one of the pairs. Chromosome 10 spans about 135 million DNA building blocks (base pairs) and represents between 4 percent and 4.5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 10 likely contains between 800 and 1,200 genes.

Genes on chromosome 10 are among the estimated 20,000 to 25,000 total genes in the human genome.

Researchers identify genes that play a role in the development of endometrial cancer

Researchers at the University of Gothenburg, Sweden, have identified two genes believed to play a role in the development of endometrial cancer. These results may eventually lead to better diagnosis and treatment of this increasingly common form of cancer.

12 Oct 2009

Researchers study the role of stem cells in development of liver cancer

Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer.

18 Sep 2009

Common gene variant linked to development of prostate cancer

Researchers have described how a common genetic variation may be involved in the development of prostate cancer.

22 Apr 2009

Discovery of new schizophrenia gene

Researchers at the Johns Hopkins University School of Medicine are one gene closer to understanding schizophrenia and related disorders.

3 Feb 2009

Discovery of second genetic risk factor for developing late-onset Alzheimer's disease

Researchers have discovered the second, strong genetic risk factor for developing late-onset Alzheimer's disease, according to a new report in the June 27th issue of the journal Cell, a Cell Press publication.

25 Jun 2008

deCODE launches novel DNA-based reference laboratory test for assessing inherited risk of type 2 diabetes

deCODE genetics has announced the launch of deCODE T2, a novel DNA-based reference laboratory test for the first common and well-validated genetic risk factor for type 2 diabetes (T2D).

16 Apr 2007

Variation in 3 genes influences risk of age-related macular degeneration

Researchers in Boston have discovered a new common, noncoding variant in the Complement Factor H (CFH) gene that is associated with age-related macular degeneration (AMD), the leading cause of irreversible visual impairment and blindness among persons aged 60 and older.

30 Aug 2006

Gene that increases risk for Alzheimer's disease

An international team of researchers, led by investigators at Washington University School of Medicine in St. Louis, are zeroing in on a gene that increases risk for Alzheimer's disease. They have identified a region of chromosome 10 that appears to be involved in risk for the disease that currently affects an estimated 4.5 million Americans.

10 Jan 2006

Scientists describe phenomenon in the human genome called transcription-induced chimerism

In the January issue of the journal Genome Research, two teams of scientists describe a widespread phenomenon in the human genome called transcription-induced chimerism (TIC), where two adjacent genes produce a single, fused RNA transcript.

6 Jan 2006

Study links low level of response (LR) to alcohol to an area on chromosome 10

How a person "feels" the effects of alcohol is, in part, genetically influenced and relates to their risk for developing alcoholism.

28 Nov 2005

Researchers have discovered a gene linked to age-related maculopathy

University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly. Their discovery suggests a simple test might be able to identify those at risk for what is commonly known as macular degeneration (AMD) and may lead to the development of more effective preventive strategies.

16 Aug 2005

Do genes play a role in determining whether a man is gay or heterosexual?

In the first-ever study combing the entire human genome for genetic determinants of male sexual orientation, a University of Illinois at Chicago researcher has identified several areas that appear to influence whether a man is heterosexual or gay.

31 Jan 2005

Search for genetic key to corneal disease

A new federal grant focusing on painful inherited visual disorders that scar the cornea will allow researchers to narrow the genetic cause of one type of corneal dystrophy and to offer improved diagnosis of this family of diseases.

8 Nov 2004

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease

Researchers at Columbia University Medical Center have found two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease. If confirmed, they will be the first genes linked to Alzheimer’s disease since ApoE4 was discovered in 1993.

8 Nov 2004