Chromosome 3 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 3, one copy inherited from each parent, form one of the pairs. Chromosome 3 spans almost 200 million base pairs (the building blocks of DNA) and represents approximately 6.5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 3 likely contains between 1,100 and 1,500 genes.

Genes on chromosome 3 are among the estimated 20,000 to 25,000 total genes in the human genome.

Further Reading

New technology reveals cellular changes across neural-epithelial-vascular complex in choroideremia

New technology reveals cellular changes across neural-epithelial-vascular complex in choroideremia

Study investigates the efficacy and safety of selpercatinib in a diverse group of patients

Study investigates the efficacy and safety of selpercatinib in a diverse group of patients

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

GnRH therapy could improve cognitive deficits in men with Down syndrome

GnRH therapy could improve cognitive deficits in men with Down syndrome

Gene variants associated with blood type may contribute to risk of early stroke

Gene variants associated with blood type may contribute to risk of early stroke

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

Genetic screening before pregnancy detects the risk in 44% of couples

Genetic screening before pregnancy detects the risk in 44% of couples

Study addresses food texture challenges in the life of children with Down syndrome

Study addresses food texture challenges in the life of children with Down syndrome

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

Simple blood test can accurately detect Alzheimer's disease in people with Down syndrome

Simple blood test can accurately detect Alzheimer's disease in people with Down syndrome

Combination of new testing methods helps identify multiple dementia risk genes

Combination of new testing methods helps identify multiple dementia risk genes

GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Research progress on the three-dimensional interaction between virus and host genome

Research progress on the three-dimensional interaction between virus and host genome

NIH researchers develop three-dimensional structure of twinkle protein

NIH researchers develop three-dimensional structure of twinkle protein

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Study shows cellular differences in brain development between modern humans and Neanderthals

Study shows cellular differences in brain development between modern humans and Neanderthals

Study identifies risks in the use of CRISPR therapeutics

Study identifies risks in the use of CRISPR therapeutics

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure