Chromosome 4 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.
Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

Non-coding genetic variant plays key role in endothelial function and disease incidence

Non-coding genetic variant plays key role in endothelial function and disease incidence

New study provides deeper insight into chromosome segregation during mitosis

New study provides deeper insight into chromosome segregation during mitosis

Failed DNA repair triggers chromosomal chaos in cancer cells

Failed DNA repair triggers chromosomal chaos in cancer cells

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

New way of identifying potential cancer drugs could streamline development of therapies

New way of identifying potential cancer drugs could streamline development of therapies

Scientists identify more aggressive chemotherapy treatment for childhood brain cancer

Scientists identify more aggressive chemotherapy treatment for childhood brain cancer

Scientists decode the longest ever continuous DNA sequence

Scientists decode the longest ever continuous DNA sequence

Down syndrome may hold important clues to onset of Alzheimer's disease

Down syndrome may hold important clues to onset of Alzheimer's disease

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Common gene variants linked to migraine risk in African-American children

Common gene variants linked to migraine risk in African-American children

Genetic link to erectile dysfunction discovered

Genetic link to erectile dysfunction discovered

Study highlights opposite effects of gene following different types of environmental events

Study highlights opposite effects of gene following different types of environmental events

Research reveals how critical oocyte quality control process works

Research reveals how critical oocyte quality control process works

DFG establishes nine new Research Units

DFG establishes nine new Research Units

New research suggests power of zebrafish as tool for cancer drug discovery

New research suggests power of zebrafish as tool for cancer drug discovery

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

New framework combines three existing methods to find cancer cell mutations

New framework combines three existing methods to find cancer cell mutations

Family genetic background essential for understanding autism progression

Family genetic background essential for understanding autism progression

Researchers describe novel mechanism that links epigenetic change to translational control

Researchers describe novel mechanism that links epigenetic change to translational control