Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 6, one copy inherited from each parent, form one of the pairs. Chromosome 6 spans about 171 million base pairs (the building blocks of DNA) and represents between 5.5 percent and 6 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 1,100 and 1,600 genes.
Genes on chromosome 6 are among the estimated 20,000 to 25,000 total genes in the human genome.
A multi-institutional study involving Massachusetts General Hospital (MGH) researchers has identified a chromosomal abnormality that appears to increase susceptibility to autism.
Fungi don't exactly come in boy and girl varieties, but they do have sex differences.
New research from the United States suggests that autism may be caused by a genetic disorder.
Researchers at UT Southwestern Medical Center are uncovering how brain cells are affected in Fragile X syndrome, the most common cause of inherited mental retardation and the most common genetic cause of autism.
The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" within a cell nucleus, according to Cornell researchers.
Loss of a small portion of chromosome 16, known as 16p11.2, is significantly associated with autism report researchers from the University of Chicago Medical Center, the University of Illinois at Chicago, and the Roswell Park Cancer Institute in an article, published Dec. 21, 2007, online by the journal Human Molecular Genetics.
Using an integrative meta-analysis approach, researchers from the Center for Bioinformatics at Peking University in Beijing have assembled the most comprehensive gene atlas underlying drug addiction and identified five molecular pathways common to four different addictive drugs.
Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model. Publishing in the Jan. 3 issue of Nature, the research team describes how trisomy 21, or Down syndrome in humans, can repress tumor growth.
Researchers in the United States say the chromosomal abnormality that affects people with Down's syndrome also protects them against cancer.
The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model.
According to new research clues to Fragile X syndrome may be connected to one single human gene.
The ALS research team at Umea University in Sweden, working with Dutch and Belgian colleagues, has found new connections between mutations in gene DPP6 and contracting the non-hereditary form of ALS. The findings are being published december 16 in Nature Genetics on the Web.
Researchers from Japan's RIKEN SNP Research Center, collaborating with a team at the University of California, San Diego (UCSD), have discovered a new genetic variation that affects a child's risk of getting Kawasaki disease (KD), an illness characterized by acute inflammation of the arteries throughout the body.
The targeted therapy Herceptin helps women with HER2+ type of breast cancer independent of whether patients have extra copies of chromosome 17, home to the HER2 gene which produces the HER2 protein that fuels cancer growth.
When humans began to migrate out of Africa about 100,000 years ago, their skin color gradually changed to adapt to their new environments.
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.
A new drug for chronic myelogenous leukemia works for patients who have developed resistance to frontline therapy and causes fewer side effects than other medications in its class, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports at the 49th annual meeting of the American Society of Hematology.
Updated clinical trial results show that the drug dasatinib (Sprycel) continues to be highly effective in patients with chronic myelogenous leukemia who were unable to tolerate Gleevec or who developed resistance to it, reports a team led by researchers at Dana-Farber Cancer Institute.
Researchers discovered genetic evidence that human evolution is speeding up – and has not halted or proceeded at a constant rate, as had been thought – indicating that humans on different continents are becoming increasingly different.
There is a clear link between GABA - a chemical substance of the central nervous system that inhibits neurons in the brain - and nicotine dependence, according to a study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.
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