Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 8, one copy inherited from each parent, form one of the pairs. Chromosome 8 spans about 146 million DNA building blocks (base pairs) and represents between 4.5 percent and 5 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 8 likely contains between 700 and 1,100 genes.
Genes on chromosome 8 are among the estimated 20,000 to 25,000 total genes in the human genome.
Scientists have created a mathematical model that can help explain why so many pregnancies and in vitro fertilization attempts fail.
Scientists have created a mathematical model that can help explain why pregnancies and in vitro fertilization attempts fail.
Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.
Amyloid is a key feature of Alzheimer's disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer's disease, according to a new study published this week.
Oxford Gene Technology announces the addition of accurate detection capabilities for translocations and difficult-to-sequence partial tandem duplications.
Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem.
A new study in Neuron offers clues to why autism spectrum disorder is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases.
Researchers have discovered that a key protein drives sperm production, knowledge that may help infertile couples conceive.
Children with aggressive blood cancers have differences -- not just in the DNA code of their blood cells -- but also in the heavily twisted protein superstructure that controls access to genes.
Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer (HPC) in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease.
A study found that children with aggressive blood cancers have different superstructures of the proteins that control gene access.
Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation.
News-Medical speaks to Dr. Dan Lavery about the LouLou Foundation, a non-profit organization dedicated to CDLK5 Deficiency Disorder.
When brains begin developing, there are a lot of moving parts -- and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism.
A canine study carried out at the University of Helsinki has described a gene variant in the regulatory region of the retina resulting in the abnormal function of retinal genes and, eventually, in the loss of vision in dogs.
It has been a widespread belief that men live a shorter life due to lifestyle choices, such as smoking and drinking alcohol. But a new study shows that men are genetically predisposed to dying younger because their Y chromosome is unable to protect an unhealthy X chromosome.
Stem cells involved in replenishing human tissues and blood depend on an enzyme known as telomerase to continue working throughout our lives. When telomerase malfunctions, it can lead to both cancer and premature aging conditions.
The spatial arrangement of genetic material within the cell nucleus plays an important role in the development of an organism.
Researchers from the University of Copenhagen have discovered that our cells replicate their DNA much more loosely than previously thought.
Abnormal formation and growth of the placenta is considered an underlying cause of various pregnancy complications such as miscarriages, preeclampsia and fetal growth restriction.