Cilia News and Research

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Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

A defect in the mechanics of motors that build tiny cellular hairs is the basis of a serious genetic disorder, according to researchers at UC Davis and Simon Fraser University, Canada.

1 Aug 2005

Cigarette smoke stops transport of freshly ovulated hamster eggs

Eggs of female hamsters are significantly less likely to be transported by the oviduct when the eggs or the oviduct have been exposed to cigarette smoke, and this could result in disruption of fertilization and pregnancy, according to reproductive scientists at the University of California, Riverside.

17 Jul 2005

Embryonic body wash controls left-right development

Humans and other animals may appear to be symmetrical on the outside, but symmetry is only skin deep. Many body organs, such as the stomach, the heart and the liver, are tipped to the right or left side. So how does the developing embryo distinguish left from right?

20 May 2005

Alcohol consumption increases movement of S. pneumoniae toward the lungs

Streptococcus pneumoniae is a bacterium that can infect the upper respiratory tract and cause pneumonia, as well as infections in other parts of the body such as the bloodstream (bacteremia), lining of the brain and spinal cord (meningitis), bones (osteomyelitis), joints (arthritis), ears (otitis media) and sinuses (sinusitis).

15 May 2005

NASA scientists find clues about kidney disease

NASA scientists and academic colleagues are studying tiny hairs inside microorganisms to find clues about kidney disease.

8 Mar 2005

Mutations in newly discovered gene, NPHP5 cause Senior-Loken syndrome

Scientists at the University of Michigan Medical School have discovered a gene called NPHP5 and found mutations in this gene that cause a rare genetic disease called Senior-Loken syndrome. Children with this syndrome develop a type of cystic kidney disease called nephronophthisis, as well as a form of blindness called retinitis pigmentosa.

3 Mar 2005

Discovery of new compounds that may treat mucus build-up associated with cystic fibrosis

Preliminary studies show these compounds improve the flow of mucus through the respiratory tract, allowing airways to clear more quickly and efficiently.

14 Nov 2004

Researchers have identified a protein in the inner ear that translates sound into the nerve impulses used by the brain

Researchers at Harvard Medical School and their colleagues report in the October 13 Nature advanced on-line edition that they have identified a protein deep in the inner ear that they believe translates sound into the nerve impulses used by the brain.

13 Oct 2004

Major step forward in understanding how the organs are placed in their correct positions in the body

Researchers at the Instituto Gulbenkian de Ciência (IGC), in Portugal, have taken a major step forward in understanding one of the fundamental questions in the field of developmental biology today: how the organs are placed in their correct positions in the body.

12 Oct 2004

Researchers have discovered that many people with Bardet-Biedl syndrome can't detect odors

Johns Hopkins researchers have discovered that many people with Bardet-Biedl syndrome (BBS), a rare, complex condition marked by an array of seemingly unconnected symptoms, including obesity, learning difficulties, eye problems and asthma, also have another, previously unreported problem

23 Aug 2004

Scientists have uncovered the identity of the last of eight genes known to contribute to Bardet-Biedl syndrome

The identification of the BBS3 gene ends the search for primary BBS-causing genes in families studied for years by a team of scientists from the United States, Canada and the United Kingdom. However, the scientists are still hunting for other, less obvious genetic influences in these families.

16 Aug 2004

Toxoplasma gondii discovery may help fight against malaria

University of North Carolina at Chapel Hill scientists have discovered a protein in the cell wall of parasites that’s crucial to the molecular mechanism allowing them to move between cells, survive and cause disease.

25 May 2004

Genome research sheds light on Bardet-Biedl syndrome

By comparing the genomes of an alga, a weed and humans, a team of researchers has identified a new gene behind Bardet-Biedl syndrome (BBS), a complex condition marked by learning disabilities, vision loss and obesity.

21 May 2004

Researchers identify new genes that control the formation of cilia found throughout the human body

Howard Hughes Medical Institute researchers have used a combination of brainpower and computer power to identify a multitude of new genes that control the formation of tiny, hair-like cilia that stipple the surfaces of many organs in a wide variety of creatures.

14 May 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004